Große or Grosse is a German surname. Notable people with the surname include:
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Aristid von Grosse (1905–1985), German nuclear chemist
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Ben Grosse, American record producer and mixer
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Carl Grosse (1768–1847), German author, translator, philosopher, and mineralogist
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Catrin G. Grosse (born 1964), German painter, graphic designer and sculptor
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Charles le Grosse (c. 1596–1650), English politician
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Christina Große (born 1970), German actress
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Demetrius Grosse (born 1981), American actor and producer
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Doris Große (born 1884), German artists' model for Ernst Ludwig Kirchner
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Fritz Große (1904–1957), German politician and diplomat
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George R. Grosse (1930–2016), American politician
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Hans-Werner Grosse (1922–2021), German bomber pilot
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Heinz-Josef Große (1947–1982), East German construction worker
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Johannes Große (born 1997), German field hockey player
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Julius Grosse (1828–1902), German poet
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Katharina Grosse (born 1961), German visual artist
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Maurice Grosse (1919–2006), British paranormal investigator
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Nina Grosse (born 1958), German film director and screenwriter
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Steffen Grosse (born 1967), German politician
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Theodor Grosse (1829–1891), German historical painter
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Twila Grosse, Canadian politician
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Ulrich Grosse (born 1953), German public transport consultant
{{surname
German-language surnames