Grapefruit Juice
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Grapefruit juice is the
juice Juice is a drink made from the extraction or pressing of the natural liquid contained in fruit and vegetables. It can also refer to liquids that are flavored with concentrate or other biological food sources, such as meat or seafood, such as ...
from grapefruits. It is rich in vitamin C and ranges from sweet-tart to very sour. Variations include white grapefruit, pink grapefruit and ruby red grapefruit juice.The World's Healthiest Foods; Grapefruit. ''The George Mateljan Foundation.'
Article
Grapefruit juice is important in medicine because of its interactions with many common drugs including caffeine and medications, which can alter how they behave in the body. Grapefruit juice is a common breakfast beverage in the United States.


Drug interactions

Grapefruit and grapefruit juice have been found to interact with numerous drugs, in many cases resulting in adverse effects. This happens in two ways: one is that grapefruit can block an enzyme which metabolizes medication, and if the drug is not metabolized, then the level of the drug in the blood can become too high, leading to an adverse effect. The other effect is that grapefruit can block the absorption of drugs in the intestine, and if the drug is not absorbed, then not enough of it is in the blood to have a therapeutic effect. One whole grapefruit or a glass of of grapefruit juice can cause drug overdose toxicity. Drugs which are incompatible with grapefruit are typically labeled on the container or
package insert A package insert is a document included in the package of a medication that provides information about that drug and its use. For prescription medications, the insert is technical, providing information for medical professionals about how to pr ...
. People taking drugs can ask their
health care provider A health care provider is an individual health professional or a health facility organization licensed to provide health care diagnosis and treatment services including medication, surgery and medical devices. Health care providers often receive ...
or
pharmacist A pharmacist, also known as a chemist (Commonwealth English) or a druggist (North American and, archaically, Commonwealth English), is a healthcare professional who prepares, controls and distributes medicines and provides advice and instructi ...
questions about grapefruit/drug interactions.


Use in cocktails

Grapefruit juice is used in several
cocktails A cocktail is an alcoholic mixed drink. Most commonly, cocktails are either a combination of spirits, or one or more spirits mixed with other ingredients such as tonic water, fruit juice, flavored syrup, or cream. Cocktails vary widely across ...
, such as the
sea breeze A sea breeze or onshore breeze is any wind that blows from a large body of water toward or onto a landmass; it develops due to differences in air pressure created by the differing heat capacities of water and dry land. As such, sea breezes ar ...
(which consists of grapefruit juice, vodka, and
cranberry juice Cranberry juice is the liquid juice of the cranberry, typically manufactured to contain sugar, water, and other fruit juices. Cranberry – a fruit native to North America – is recognized for its bright red color, tart taste, and versat ...
); the salty dog,David Tanis, ''Heart of the Artichoke and Other Kitchen Journeys'' ( Workman: 2010), p. 320. the grapefruit
mimosa ''Mimosa'' is a genus of about 590 species of herbs and shrubs, in the mimosoid clade of the legume family Fabaceae. The generic name is derived from the Greek word (''mimos''), an "actor" or "mime", and the feminine suffix -''osa'', "resembl ...
, and a grapefruit
radler Shandy is beer or cider mixed with a lemon or a lemon-lime flavored beverage. The citrus beverage, often called lemonade, may or may not be carbonated. The proportions of the two ingredients are adjusted to taste but are usually half lemonade ...
.


Canadian regulations

Canadian regulations on commercially produced and sold grapefruit juice are that it must be made from clean, mature grapefruit and may contain sugar,
invert sugar Inverted sugar syrup, also called invert syrup, invert sugar, simple syrup, sugar syrup, sugar water, bar syrup, syrup USP, or sucrose inversion, is a syrup mixture of the monosaccharides glucose and fructose, that is made by hydrolytic sa ...
, dextrose, glucose solids and class II preservativesclass II preservative
/ref> such as benzoic acid, amylase, cellulase and pectinase. According to Canadian standards, grapefruit juice should contain more than 1.15 milliequivalents of free amino acid per ; more than 70 milligrams of potassium per 100 ml; and have an absorbance value for total polyphenolics of no less than 0.310. During the production process, the sugar content in the juice, before the addition of sugar, invert sugar, dextrose or glucose solids, should have a
Brix Degrees Brix (symbol °Bx) is a measure of the dissolved solids in a liquid, and is commonly used to measure dissolved sugar content of an aqueous solution. One degree Brix is 1 gram of sucrose in 100 grams of solution and represents the strength ...
reading of no less than 9.3. It must contain 0.7% to 2.1% of acid by weight as anhydrous citric acid.


See also

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Grapefruit spoon A grapefruit spoon is a utensil usually similar in design to a teaspoon that tapers to a sharp edge or teeth, the intent of the front serration Serration is a saw-like appearance or a row of sharp or tooth-like projections. A serrated cu ...
*
Juicing Juicing is the process of extracting juice from plant tissues such as fruit or vegetables. Overview There are many methods of juicing, from squeezing fruit by hand to wide-scale extraction with industrial equipment. Juicing is generally the ...
*
List of juices This is a list of juices. Juice is a liquid that is naturally contained in fruit and vegetables. It can also refer to liquids that are flavored with these or other biological food sources such as meat and seafood. It is commonly consumed as a bever ...


References


External links

* {{citrus Fruit juice Grapefruit Citrus drinks CYP3A4 inhibitors