Gideon John Davies (born 6 July 1964) is a Professor of Chemistry in the

Structural Biology Structural biology is a field that is many centuries old which, and as defined by the Journal of Structural Biology, deals with structural analysis of living material (formed, composed of, and/or maintained and refined by living cells) at every le ...

Laboratory (YSBL) at the

University of York , mottoeng = On the threshold of wisdom , established = , type = Public research university , endowment = £8.0 million , budget = £403.6 million , chancellor = Heather Melville , vice_chancellor = Charlie Jeffery , students ...

, UK. Davies is best known for his ground-breaking studies into carbohydrate-active enzymes, notably analysing the conformational and mechanistic basis for catalysis and applying this for societal benefit. In 2016 Davies was apppointed the

Royal Society The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, re ...

Ken Murray Research Professor at the University of York.

Education

Davies was educated at the

University of Bristol , mottoeng = earningpromotes one's innate power (from Horace, ''Ode 4.4'') , established = 1595 – Merchant Venturers School1876 – University College, Bristol1909 – received royal charter , type ...

where he was awarded a

Bachelor of Science A Bachelor of Science (BS, BSc, SB, or ScB; from the Latin ') is a bachelor's degree awarded for programs that generally last three to five years. The first university to admit a student to the degree of Bachelor of Science was the University of ...

degree in

Biochemistry Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology and ...

and a

PhD PHD or PhD may refer to: * Doctor of Philosophy (PhD), an academic qualification Entertainment * '' PhD: Phantasy Degree'', a Korean comic series * ''Piled Higher and Deeper'', a web comic * Ph.D. (band), a 1980s British group ** Ph.D. (Ph.D. albu ...

in 1990 for research on the enzyme

phosphoglycerate kinase Phosphoglycerate kinase () (PGK 1) is an enzyme that catalyzes the reversible transfer of a phosphate group from 1,3-bisphosphoglycerate (1,3-BPG) to ADP producing 3-phosphoglycerate (3-PG) and ATP : :1,3-bisphosphoglycerate + ADP glycera ...

isolated from the bacterium ''

Bacillus stearothermophilus ''Geobacillus stearothermophilus'' (previously ''Bacillus stearothermophilus'') is a rod-shaped, Gram-positive bacterium and a member of the phylum Bacillota. The bacterium is a thermophile and is widely distributed in soil, hot springs, ocean s ...

'', and supervised by Herman Watson and Len Hall. He was awarded a Doctor of Science (DSc) degree from the

in 2007.

Career

Following his PhD, Davies did

postdoctoral research A postdoctoral fellow, postdoctoral researcher, or simply postdoc, is a person professionally conducting research after the completion of their doctoral studies (typically a PhD). The ultimate goal of a postdoctoral research position is to p ...

at the European Molecular Biology Laboratory (EMBL) outstation in Hamburg working with Keith S. Wilson on the use of

synchrotron radiation Synchrotron radiation (also known as magnetobremsstrahlung radiation) is the electromagnetic radiation emitted when relativistic charged particles are subject to an acceleration perpendicular to their velocity (). It is produced artificially in ...

protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...

crystallography Crystallography is the experimental science of determining the arrangement of atoms in crystalline solids. Crystallography is a fundamental subject in the fields of materials science and solid-state physics (condensed matter physics). The wor ...

and also at the

French National Centre for Scientific Research The French National Centre for Scientific Research (french: link=no, Centre national de la recherche scientifique, CNRS) is the French state research organisation and is the largest fundamental science agency in Europe. In 2016, it employed 31,637 ...

(CNRS) in

Grenoble lat, Gratianopolis , commune status = Prefecture and commune , image = Panorama grenoble.png , image size = , caption = From upper left: Panorama of the city, Grenoble’s cable cars, place Saint- ...

. in 1990, Davies moved to York to work with Dale Wigley and

Guy Dodson George Guy Dodson Fellow of the Royal Society, FRS FMedSci (13 January 1937 – 24 December 2012), was a British biochemist who specialised in X-ray crystallography#Biological macromolecular crystallography, protein crystallography at the Univer ...

DNA gyrase DNA gyrase, or simply gyrase, is an enzyme Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrat ...

, starting his own group within YSBL in 1996 upon receiving a

Royal Society University Research Fellowship __NOTOC__ The Royal Society University Research Fellowship (URF) is a research fellowship awarded to outstanding early career scientists in the United Kingdom who are judged by the Royal Society to have the potential to become leaders in their fie ...

. He was appointed Professor at the University of York in 2001 and awarded a Royal Society Ken Murray Research Professorship in 2016. He has collaborated with Alywn Jones, Bernard Henrissat, Steve Withers and David Vocadlo. Among those who undertook doctoral research with him are

Tracey Gloster Tracey Maureen Gloster is a chemist at the University of St Andrews UK. Her research interests are in structural biology, chemical biology, glycobiology and carbohydrate processing enzymes. Education Gloster studied biochemistry at University of ...

Research

Davies research investigates the

biological chemistry Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology and ...

carbohydrate In organic chemistry, a carbohydrate () is a biomolecule consisting of carbon (C), hydrogen (H) and oxygen (O) atoms, usually with a hydrogen–oxygen atom ratio of 2:1 (as in water) and thus with the empirical formula (where ''m'' may or ma ...

s, from their structure to their roles in

enzymology Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...

glycobiology Defined in the narrowest sense, glycobiology is the study of the structure, biosynthesis, and biology of saccharides (sugar chains or glycans) that are widely distributed in nature. Sugars or saccharides are essential components of all living thing ...

, use as

biofuel Biofuel is a fuel that is produced over a short time span from biomass, rather than by the very slow natural processes involved in the formation of fossil fuels, such as oil. According to the United States Energy Information Administration (E ...

s and implications for gut microbiota. His research has been funded by the Biotechnology and Biological Sciences Research Council (BBSRC),UK Government research grants awarded to Gideon Davies
, via

Research Councils UK Research Councils UK, sometimes known as RCUK, was a non-departmental public body which coordinated science policy in the United Kingdom from 2002 to 2018. It was an umbrella organisation that coordinated the seven separate research councils tha ...

European Research Council (ERC) and

Alzheimer's Research UK Alzheimer's Research UK (ARUK) is a dementia research charity in the United Kingdom, founded in 1992 as the Alzheimer's Research Trust. ARUK funds scientific studies to find ways to treat, cure or prevent all forms of dementia, including Alzhei ...

. Davies has over 340 publications in peer reviewed journals.

Awards and honours

Davies has won a number of awards for his work. These include The

Davy Medal The Davy Medal is awarded by the Royal Society of London "for an outstandingly important recent discovery in any branch of chemistry". Named after Humphry Davy, the medal is awarded with a monetary gift, initially of £1000 (currently £2000). H ...

and

Gabor Medal The Gabor Medal is one of the medals awarded by the Royal Society for "acknowledged distinction of interdisciplinary work between the life sciences with other disciplines". The medal was created in 1989 to honor the memory of physicist Denni ...

of the

, the John and Rita Cornforth Award (with Paul Walton), the Haworth Memorial, Khorana, Peptide and Protein, Corday-Morgan and Carbohydrate Chemistry medals of the

Royal Society of Chemistry The Royal Society of Chemistry (RSC) is a learned society (professional association) in the United Kingdom with the goal of "advancing the chemistry, chemical sciences". It was formed in 1980 from the amalgamation of the Chemical Society, the Ro ...

, the iChemE Global Energy Award of the

Institution of Chemical Engineers The Institution of Chemical Engineers (IChemE) is a global professional engineering institution with over 33,000 members worldwide. It was founded in 1922 and awarded a Royal Charter in 1957. It has offices in Rugby, London, Melbourne, Wellingto ...

(with Paul Walton and Bernard Henrissat), The Whistler Prize of the International Carbohydrate Organization, and the GlaxoSmithKline Award of the

Biochemical Society The Biochemical Society is a learned society in the United Kingdom in the field of biochemistry, including all the cellular and molecular biosciences. Structure It currently has around 7000 members, two-thirds in the UK. It is affiliated with th ...

. In 2019 he was one of the members of the York Structural Biology Laboratory at the

that received the

Queen's Anniversary Prize The Queen's Anniversary Prizes for Higher and Further Education are a biennially awarded series of prizes awarded to universities and colleges in the further and higher education sectors within the United Kingdom. Uniquely it forms part of the Bri ...

. Davies was elected a member of the European Molecular Biology Organization (EMBO) in 2010 and is a

Fellow of the Royal Society of Chemistry Fellowship of the Royal Society of Chemistry (FRSC) is an award conferred by the Royal Society of Chemistry (RSC) in the United Kingdom. FRSC award Achieving Fellow status in the chemical profession denotes to the wider community a high level of ...

(FRSC) In 2010, Davies was elected a Fellow of the Royal Society (FRS). His nomination reads: Davies was elected a Fellow of the Academy of Medical Sciences (FMedSci) in 2014, his nomination reads He was awarded the John and Rita Cornforth Award of Royal Society of Chemistry in 2020 and the

(to YSBL) in 2019 He was a Haworth Memorial Lectureship of Royal Society of Chemistry in 2018 and a Global Energy Award of Institution of Chemical Engineers winner in 2016.

Personal life

Davies married Valérie Marie-Andrée Ducros in 1999 (div. 2021) and has two daughters.

References

{{DEFAULTSORT:Davies, Gideon John Living people Fellows of the Royal Society Fellows of the Academy of Medical Sciences (United Kingdom) Academics of the University of York Members of the European Molecular Biology Organization Fellows of the Royal Society of Chemistry 1964 births British biochemists Biophysicists