|
Gabor Medal
The Gabor Medal is one of the medals awarded by the Royal Society for "acknowledged distinction of interdisciplinary work between the life sciences with other disciplines". The medal was created in 1989 to honor the memory of physicist Dennis Gabor, and was originally awarded biennially. Initially awarded "for acknowledged distinction of work in the life sciences, particularly in the fields of genetic engineering and molecular biology", the criteria for the awarding of the medal were later changed to its current definition. It is made of silver. The medal is targeted at "emerging early to mid career stage scientist and is accompanied by a £2000 prize since 2017. Before that, it accompanied with a prize of £1000. From 2017 it has been awarded annually. All citizens who have been residents of either United Kingdom, Commonwealth of Nations, or the Republic of Ireland for more than three years are eligible for the medal. The Gabor Medal was first awarded in 1989 to Noreen Murr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dennis Gabor 1971b
Dennis or Denis is a first or last name from the Greco-Roman name Dionysius, via one of the Christian saints named Dionysius. The name came from Dionysus, the Greek god of ecstatic states, particularly those produced by wine, which is sometimes said to be derived from the Greek Dios (Διός, "of Zeus") and Nysos or Nysa (Νῦσα), where the young god was raised. Dionysus (or Dionysos; also known as Bacchus in Roman mythology and associated with the Italic Liber), the Thracian god of wine, represents not only the intoxicating power of wine, but also its social and beneficent influences. He is viewed as the promoter of civilization, a lawgiver, and lover of peace—as well as the patron deity of both agriculture and the theater. Dionysus is a god of mystery religious rites, such as those practiced in honor of Demeter and Persephone at Eleusis near Athens. In the Thracian mysteries, he wears the "bassaris" or fox-skin, symbolizing new life. (See also Maenads.) A mediaeva ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein Engineering
Protein engineering is the process of developing useful or valuable proteins. It is a young discipline, with much research taking place into the understanding of protein folding and recognition for protein design principles. It has been used to improve the function of many enzymes for industrial catalysis. It is also a product and services market, with an estimated value of $168 billion by 2017. There are two general strategies for protein engineering: rational protein design and directed evolution. These methods are not mutually exclusive; researchers will often apply both. In the future, more detailed knowledge of protein structure and function, and advances in high-throughput screening, may greatly expand the abilities of protein engineering. Eventually, even unnatural amino acids may be included, via newer methods, such as expanded genetic code, that allow encoding novel amino acids in genetic code. Approaches Rational design In rational protein design, a scientist ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Columbia University Press
Columbia University Press is a university press based in New York City, and affiliated with Columbia University. It is currently directed by Jennifer Crewe (2014–present) and publishes titles in the humanities and sciences, including the fields of literary and cultural studies, history, social work, sociology, religion, film, and international studies. History Founded in May 1893, In 1933 the first four volumes of the ''History of the State of New York'' were published. In early 1940s revenues rises, partially thanks to the ''Encyclopedia'' and the government's purchase of 12,500 copies for use by the military. Columbia University Press is notable for publishing reference works, such as ''The Columbia Encyclopedia The ''Columbia Encyclopedia'' is a one-volume encyclopedia produced by Columbia University Press and, in the last edition, sold by the Gale Group. First published in 1935, and continuing its relationship with Columbia University, the encyclopedi ...'' (1935 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Endonuclease
Endonucleases are enzymes that cleave the phosphodiester bond within a polynucleotide chain. Some, such as deoxyribonuclease I, cut DNA relatively nonspecifically (without regard to sequence), while many, typically called restriction endonucleases or restriction enzymes, cleave only at very specific nucleotide sequences. Endonucleases differ from exonucleases, which cleave the ends of recognition sequences instead of the middle (endo) portion. Some enzymes known as "exo-endonucleases", however, are not limited to either nuclease function, displaying qualities that are both endo- and exo-like. Evidence suggests that endonuclease activity experiences a lag compared to exonuclease activity. Restriction enzymes are endonucleases from eubacteria and archaea that recognize a specific DNA sequence. The nucleotide sequence recognized for cleavage by a restriction enzyme is called the restriction site. Typically, a restriction site will be a palindromic sequence about four to six nucleot ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Methylation
In the chemical sciences, methylation denotes the addition of a methyl group on a substrate, or the substitution of an atom (or group) by a methyl group. Methylation is a form of alkylation, with a methyl group replacing a hydrogen atom. These terms are commonly used in chemistry, biochemistry, soil science, and the biological sciences. In biological systems, methylation is catalyzed by enzymes; such methylation can be involved in modification of heavy metals, regulation of gene expression, regulation of protein function, and RNA processing. In vitro methylation of tissue samples is also one method for reducing certain histological staining artifacts. The reverse of methylation is demethylation. In biology In biological systems, methylation is accomplished by enzymes. Methylation can modify heavy metals, regulate gene expression, RNA processing and protein function. It has been recognized as a key process underlying epigenetics. Methanogenesis Methanogenesis, the proces ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Transcription (genetics)
Transcription is the process of copying a segment of DNA into RNA. The segments of DNA transcribed into RNA molecules that can encode proteins are said to produce messenger RNA (mRNA). Other segments of DNA are copied into RNA molecules called non-coding RNAs (ncRNAs). mRNA comprises only 1–3% of total RNA samples. Less than 2% of the human genome can be transcribed into mRNA ( Human genome#Coding vs. noncoding DNA), while at least 80% of mammalian genomic DNA can be actively transcribed (in one or more types of cells), with the majority of this 80% considered to be ncRNA. Both DNA and RNA are nucleic acids, which use base pairs of nucleotides as a complementary language. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, antiparallel RNA strand called a primary transcript. Transcription proceeds in the following general steps: # RNA polymerase, together with one or more general transcription factors, binds to promoter ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adrian Bird
Sir Adrian Peter Bird, (born 3 July 1947) is a British geneticist and Buchanan Professor of Genetics at the University of Edinburgh. Bird has spent much of his academic career in Edinburgh, from receiving his PhD in 1970 to working at the MRC Mammalian Genome Unit and later serving as director of the Wellcome Trust Centre for Cell Biology. His research focuses on understanding DNA methylation and CpG islands, and their role in diseases such as Rett syndrome. Education and early life Bird was born in Rowley Regis near Wolverhampton, England, but from age 4 lived in the town of Kidderminster, near Birmingham. He attended a grammar school in Hartlebury, achieving grades CCD for his A-level results. Whilst at school, Bird played cricket and hockey for a local team. Bird received his PhD from the University of Edinburgh in 1970 for research supervised by Max Birnstiel, following undergraduate study of Biochemistry at the University of Sussex. Career and research Following his P ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Times Higher Education
''Times Higher Education'' (''THE''), formerly ''The Times Higher Education Supplement'' (''The Thes''), is a British magazine reporting specifically on news and issues related to higher education. Ownership TPG Capital acquired TSL Education from Charterhouse in a £400 million deal in July 2013 and rebranded TSL Education, of which Times Higher Education was a part, as TES Global. The acquisition by TPG marked the third change of ownership in less than a decade for Times Higher Education, which was previously owned by News International before being acquired by Exponent Private Equity in 2005. In March 2019, private equity group Inflexion Pvt. Equity Partners LLP acquired Times Higher Education from TPG Capital, becoming THE's fourth owners in 15 years. Following the acquisition by the private equity group, Times Higher Education was carved out as an independent entity from TES Global. The investment was made by Inflexion's dedicated mid-market buyout funds. The exclusive ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Synchrotron Radiation
Synchrotron radiation (also known as magnetobremsstrahlung radiation) is the electromagnetic radiation emitted when relativistic charged particles are subject to an acceleration perpendicular to their velocity (). It is produced artificially in some types of particle accelerators, or naturally by fast electrons moving through magnetic fields. The radiation produced in this way has a characteristic polarization and the frequencies generated can range over a large portion of the electromagnetic spectrum. Synchrotron radiation is similar to bremsstrahlung radiation, which is emitted by a charged particle when the acceleration is parallel to the direction of motion. The general term for radiation emitted by particles in a magnetic field is ''gyromagnetic radiation'', for which synchrotron radiation is the ultra-relativistic special case. Radiation emitted by charged particles moving non-relativistically in a magnetic field is called cyclotron emission. For particles in the mild ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polyketide
Polyketides are a class of natural products derived from a precursor molecule consisting of a chain of alternating ketone (or reduced forms of a ketone) and methylene groups: (-CO-CH2-). First studied in the early 20th century, discovery, biosynthesis, and application of polyketides has evolved. It is a large and diverse group of secondary metabolites caused by its complex biosynthesis which resembles that of fatty acid synthesis. Because of this diversity, polyketides can have various medicinal, agricultural, and industrial applications. Many polyketides are medicinal or exhibit acute toxicity. Biotechnology has enabled discovery of more naturally-occurring polyketides and evolution of new polyketides with novel or improved bioactivity. History Naturally produced polyketides by various plants and organisms have been used by humans since before studies on them began in the 19th and 20th century. In 1893, J. Norman Collie synthesized detectable amounts of orcinol by heating d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Streptomyces
''Streptomyces'' is the largest genus of Actinomycetota and the type genus of the family Streptomycetaceae. Over 500 species of ''Streptomyces'' bacteria have been described. As with the other Actinomycetota, streptomycetes are gram-positive, and have genomes with high GC content. Found predominantly in soil and decaying vegetation, most streptomycetes produce spores, and are noted for their distinct "earthy" odor that results from production of a volatile metabolite, geosmin. Streptomycetes are characterised by a complex secondary metabolism. They produce over two-thirds of the clinically useful antibiotics of natural origin (e.g., neomycin, streptomycin, cypemycin, grisemycin, bottromycins and chloramphenicol). The antibiotic streptomycin takes its name directly from ''Streptomyces''. Streptomycetes are infrequent pathogens, though infections in humans, such as mycetoma, can be caused by '' S. somaliensis'' and '' S. sudanensis'', and in plants can be caused by ' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
.jpg "Click for more on -> Columbia University Press"){kind=logo}
