Gas Phase Electrophoretic Molecular Mobility Analysis
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Gas phase electrophoretic molecular mobility analysis (GEMMA) is a method for chemical analysis in which nanoflow
electrospray ionization Electrospray ionization (ESI) is a technique used in mass spectrometry to produce ions using an electrospray in which a high voltage is applied to a liquid to create an aerosol. It is especially useful in producing ions from macromolecules becaus ...
creates highly charged
ion An ion () is an atom or molecule with a net electrical charge. The charge of an electron is considered to be negative by convention and this charge is equal and opposite to the charge of a proton, which is considered to be positive by conven ...
s from
macromolecule A macromolecule is a very large molecule important to biophysical processes, such as a protein or nucleic acid. It is composed of thousands of covalently bonded atoms. Many macromolecules are polymers of smaller molecules called monomers. The ...
s that are charge reduced and separated in a
differential mobility analyzer Ion mobility spectrometry (IMS) is an analytical technique used to separate and identify ionized molecules in the gas phase based on their mobility in a carrier buffer gas. Though heavily employed for military or security purposes, such as detect ...
.


See also

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Ion-mobility spectrometry–mass spectrometry Ion mobility spectrometry–mass spectrometry (IMS-MS) is an analytical chemistry method that separates gas phase ions based on their interaction with a collision gas and their masses. In the first step, the ions are separated according to their mob ...
* Differential mobility detector *
Particle mass analyser Particle mass analyser is a measurement technique for classifying aerosol particles according to their mass-to-charge ratio. Techniques exist for classifying (selecting) aerosol particles in the sub 1,000 nm range according to electrical mobi ...
*
Electrical mobility Electrical mobility is the ability of charged particles (such as electrons or protons) to move through a medium in response to an electric field that is pulling them. The separation of ions according to their mobility in gas phase is called ion ...
*
Electrical aerosol spectrometer Electrical aerosol spectrometry (EAS) is a technique for measurement of the number-size distribution of aerosol using a combination of electrical charging and multiple solid state electrometer detectors. The technique combines both diffusion and fi ...


References

Mass spectrometry Laboratory techniques {{physical-chemistry-stub