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Franciscus (Franz) Cornelius Donders FRS
FRSE Fellowship of the Royal Society of Edinburgh (FRSE) is an award granted to individuals that the Royal Society of Edinburgh, Scotland's national academy of science and letters, judged to be "eminently distinguished in their subject". This soc ...
(27 May 1818 – 24 March 1889) was a Dutch
ophthalmologist Ophthalmology ( ) is a surgical subspecialty within medicine that deals with the diagnosis and treatment of eye disorders. An ophthalmologist is a physician who undergoes subspecialty training in medical and surgical eye care. Following a medic ...
. During his career, he was a professor of
physiology Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemica ...
in
Utrecht Utrecht ( , , ) is the fourth-largest city and a municipality of the Netherlands, capital and most populous city of the province of Utrecht. It is located in the eastern corner of the Randstad conurbation, in the very centre of mainland Nethe ...
, and was internationally regarded as an authority on
eye disease This is a partial list of human eye diseases and disorders. The World Health Organization publishes a classification of known diseases and injuries, the International Statistical Classification of Diseases and Related Health Problems, or ICD-10. ...
s, directing the Netherlands Hospital for Eye Patients. Along with Graefe and
Helmholtz Hermann Ludwig Ferdinand von Helmholtz (31 August 1821 – 8 September 1894) was a German physicist and physician who made significant contributions in several scientific fields, particularly hydrodynamic stability. The Helmholtz Association, ...
, he was one of the primary founders of scientific
ophthalmology Ophthalmology ( ) is a surgical subspecialty within medicine that deals with the diagnosis and treatment of eye disorders. An ophthalmologist is a physician who undergoes subspecialty training in medical and surgical eye care. Following a medic ...
.


Life

He was born in
Tilburg Tilburg () is a city and municipality in the Netherlands, in the southern province of North Brabant. With a population of 222,601 (1 July 2021), it is the second-largest city or municipality in North Brabant after Eindhoven and the seventh-lar ...
, the son of Jan Franz Donders and Agnes Elizabeth Hegh. He was educated at Duizel School and seminaries in both Tilburg and
Boxmeer Boxmeer () is a town and former municipality in upper southeastern Netherlands. Boxmeer as a municipality incorporated the former municipality of Beugen en Rijkevoort and that of Vierlingsbeek. In Overloon is the Overloon War Museum. Boxmeer, C ...
. By the age of seventeen, Franciscus Donders had started studying medicine in the School of Military in Utrecht. It was here that he discovered his passion for experimental study, specifically in the field of chemistry. By the age of twenty-two he entered the junior military in order to become a surgeon For several years, the young Donders studied at the Royal Dutch Hospital for Military Medicine in
Utrecht Utrecht ( , , ) is the fourth-largest city and a municipality of the Netherlands, capital and most populous city of the province of Utrecht. It is located in the eastern corner of the Randstad conurbation, in the very centre of mainland Nethe ...
, then earning his M.D. in 1840 from the
University of Leiden Leiden University (abbreviated as ''LEI''; nl, Universiteit Leiden) is a public research university in Leiden, Netherlands. The university was founded as a Protestant university in 1575 by William, Prince of Orange, as a reward to the city of L ...
. Following a stint as a medical officer in
the Hague The Hague ( ; nl, Den Haag or ) is a city and municipality of the Netherlands, situated on the west coast facing the North Sea. The Hague is the country's administrative centre and its seat of government, and while the official capital of ...
, in 1842 he was appointed as a lecturer in physiology and
anatomy Anatomy () is the branch of biology concerned with the study of the structure of organisms and their parts. Anatomy is a branch of natural science that deals with the structural organization of living things. It is an old science, having it ...
at the Utrecht military medical school. Because of his accomplishments in his studies, he made good connections that would allow for him to study his own scientific work. Soon after doing that he became a Professor for Anatomy and Physiology in 1847 at Utrecht University. In 1847, he became an associate professor at
Utrecht University Utrecht University (UU; nl, Universiteit Utrecht, formerly ''Rijksuniversiteit Utrecht'') is a public research university in Utrecht, Netherlands. Established , it is one of the oldest universities in the Netherlands. In 2018, it had an enrollm ...
and, in 1862, attained a full professorship in physiology. In 1847, he became correspondent of the Royal Institute of the Netherlands, when that became the
Royal Netherlands Academy of Arts and Sciences The Royal Netherlands Academy of Arts and Sciences ( nl, Koninklijke Nederlandse Akademie van Wetenschappen, abbreviated: KNAW) is an organization dedicated to the advancement of science and literature in the Netherlands. The academy is housed ...
; in 1851, he joined as member. Donders knew that textbook knowledge had a lot to offer the field of cognition, but he also knew that it would be enhanced and hold more validity if experiments were involved. Donders was the first to discover that a lot of time is needed for an abstract mental process to occur. He is known for his work and research of
eye disease This is a partial list of human eye diseases and disorders. The World Health Organization publishes a classification of known diseases and injuries, the International Statistical Classification of Diseases and Related Health Problems, or ICD-10. ...
and was among the first practitioners of the
ophthalmoscope Ophthalmoscopy, also called funduscopy, is a test that allows a health professional to see inside the fundus of the eye and other structures using an ophthalmoscope (or funduscope). It is done as part of an eye examination and may be done as part ...
. He is credited with invention of an impression
tonometer Tonometry is the procedure eye care professionals perform to determine the intraocular pressure (IOP), the fluid pressure inside the eye. It is an important test in the evaluation of patients at risk from glaucoma. Most tonometers are calibrated ...
(1862), and for introduction of prismatic and cylindrical lenses for treatment of
astigmatism Astigmatism is a type of refractive error due to rotational asymmetry in the eye's refractive power. This results in distorted or blurred vision at any distance. Other symptoms can include eyestrain, headaches, and trouble driving at night ...
(1860). Donders also was the first to use differences in human
reaction time Mental chronometry is the scientific study of processing speed or reaction time on cognitive tasks to infer the content, duration, and temporal sequencing of mental operations. Reaction time (RT; sometimes referred to as "response time") is meas ...
to infer differences in cognitive processing. He tested both simple reaction time and choice reaction time, finding that simple reaction was faster. This concept is now one of the central tenets of cognitive psychology while
mental chronometry Mental chronometry is the scientific study of processing speed or reaction time on cognitive tasks to infer the content, duration, and temporal sequencing of mental operations. Reaction time (RT; sometimes referred to as "response time") is meas ...
is not a topic in itself, it is one of the most common tools used for making inferences about processes such as learning, memory, and attention. Using reaction time, Donders constructed what is known as reaction time, and three distinct ways to analyze it. The common version was task A (simple). When Donders’s conducted task A, he stimulated the participant’s foot in order to measure the fastest hand reaction. Participants were made known ahead of time that they would be measuring how fast the response of their hand was (which enabled them to better sense the stimulation). Donder’s task B (choice) consisted of stimulation in the right hand and measuring the response of the right foot. This task had the same goals as task A; On top of that the subject’s ability to discriminate the stimulus and point out the stimulus was also measured and requires the intervention of a response decision. The third distinct task was known as the C task (Go/No-go task) To analyze this task Donder stimulated the both feet of participants. Participants were asked to respond with their right hand when they felt stimulation in the right foot, but not to do the same with the left side. This task was also designed to measure the participants ability to detect stimuli and offer the requested response. Donders’s task C cannot be performed without intervention of stimulus discrimination occurring within the sensory and motor process. He represents the durations of these processes labeling them as a-, b- and c- methods (example a/-a = eat/don’t eat) In order to utilize these methods Donders used the speech repetition task Different patterns were used for different methods. The pattern of reaction time is aHerman Snellen Herman Snellen (February 19, 1834 – January 18, 1908) was a Dutch ophthalmologist who introduced the Snellen chart to study visual acuity (1862). He took over directorship of the Netherlands Hospital for Eye Patients (Nederlandsch Gasthuis voo ...
. In 1864, he published the highly acclaimed "On the anomalies of accommodation and refraction of the eye". This book was written in 1864 and focused on separated errors of refraction and accommodation. The publication of this book enabled the vending of eye glass fittings to be the service of ophthalmology. "Ophthalmology is a branch of medicine and surgery which deals with the diagnosis and treatment of eye disorders." Franciscus Donders spent a lot of time studying and researching biology and cognition. Only a little amount of his time was spent studying ophthalmology. Although little, its impact was the parent of many concepts (that still exist) in the field of ophthalmology. He introduced subjects such as refraction, astigmatism, accommodation, ametropia, hypermetropia, aphakia, presbyopia, convergence, and squint. He is also responsible for the formula that equates the sharpness of one’s vision. It was in 1864 when Donders’s was able to introduce accommodation of the Eye, and refraction. Donders taught that the retina uses rays in order to come together. This occurs behind the retina and is what allows us to perceive nearby objects. Once those rays have been perceived they are then able to bring more rays into the retina. This is known as the power of accommodation of the eye. This was significant because it created what is now known as scientific Ophthalmology. Of the concepts he introduced, the most important is Donder’s Law. His name is associated with "Donders' law", which states that "the rotation of the eyeball is determined by the distance of the object from the median plane and the line of the horizon". It contains 3 specific dimensions that orientate the eye for whichever way it looks. It also states that the orientation of the eye has no correlation with the starting point. If the eye is constantly looking at the same thing, the orientation of the eye will also remain the same. The law assures that the eye focuses on far away targets (with an upright head) and adapts to a special angle for each glaze that occurs; even though there are numerous ways eyes could position. Other contributions to the field of ophthalmology include: the translation of German textbooks to Dutch, the clinical application within the field, acknowledgment of glaucoma and its subtypes, analysis of brain function, and the reduced eye model. He is also well recognized in the dental community for naming the "space of Donders", the space between the dorsum of the tongue and the
hard palate The hard palate is a thin horizontal bony plate made up of two bones of the facial skeleton, located in the roof of the mouth. The bones are the palatine process of the maxilla and the horizontal plate of palatine bone. The hard palate spans ...
when the
mandible In anatomy, the mandible, lower jaw or jawbone is the largest, strongest and lowest bone in the human facial skeleton. It forms the lower jaw and holds the lower tooth, teeth in place. The mandible sits beneath the maxilla. It is the only movabl ...
is at rest. He died in
Utrecht Utrecht ( , , ) is the fourth-largest city and a municipality of the Netherlands, capital and most populous city of the province of Utrecht. It is located in the eastern corner of the Randstad conurbation, in the very centre of mainland Nethe ...
.


Family

He married twice: first in 1845 to Ernestine Zimmerman (d.1887); secondly, in 1888 to Abrahamine Arnolda Louisa Hubrecht.


References

* * * * * den Tonkelaar, Isolde, Harold E. Henkes and Gijsbert K. van Leersum (1996) - ''Eye and instruments : Nineteenth-century ophthalmological instruments in the Netherlands.'' Amsterdam : Batavian Lion. . 304 pgs.


External links

* * * B. Theunissen
Franciscus Cornelis Donders 1818-1889
F.C. Donders: turning refracting into science, @ History of science and scholarship in the Netherlands.
Picture, biography, bibliography and digitized sources
in the
Virtual Laboratory The online project Virtual Laboratory. Essays and Resources on the Experimentalization of Life, 1830-1930, located at the Max Planck Institute for the History of Science, is dedicated to research in the history of the experimentalization of life. Th ...
of the
Max Planck Institute for the History of Science The Max Planck Institute for the History of Science (German: Max-Planck-Institut für Wissenschaftsgeschichte) is a scientific research institute founded in March 1994. It is dedicated to addressing fundamental questions of the history of knowledg ...
* P. Eling,
Donders, Frans (1818-1889)
Geneeskundige en fysioloog. * Edwin Maes

Gravesite of Franciscus Donders. * Obituary in: {{DEFAULTSORT:Donders, Franciscus Cornelis 1818 births 1889 deaths Dutch ophthalmologists Dutch physiologists Foreign Members of the Royal Society Members of the French Academy of Sciences Members of the Royal Netherlands Academy of Arts and Sciences People from Tilburg Physicians from Utrecht (city) Utrecht University alumni Utrecht University faculty