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Friedrich Wegener (7 April 1907,
Varel Varel () is a town in the district of Friesland, in Lower Saxony, Germany. It is situated near the Jade River and the Jade Bight, approximately south of Wilhelmshaven and north of Oldenburg. With a population of 23,984 (2020) it is the biggest ...
– 9 July 1990,
Lübeck Lübeck (; Low German also ), officially the Hanseatic City of Lübeck (german: Hansestadt Lübeck), is a city in Northern Germany. With around 217,000 inhabitants, Lübeck is the second-largest city on the German Baltic coast and in the stat ...
, ) was a German
pathologist Pathology is the study of the causal, causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when us ...
who is notable for his description of a
rare disease A rare disease is any disease that affects a small percentage of the population. In some parts of the world, an orphan disease is a rare disease whose rarity means there is a lack of a market large enough to gain support and resources for discove ...
originally referred to Wegener disease and now referred to as
granulomatosis with polyangiitis Granulomatosis with polyangiitis (GPA), previously known as Wegener's granulomatosis (WG), is a rare long-term systemic disorder that involves the formation of granulomas and inflammation of blood vessels (vasculitis). It is a form of vasculitis ...
. Although this disease was known before Wegener's description, from the 1950s onwards it was generally referred to as Wegener's granulomatosis.


Biography


Early life

Friedrich Wegener was born on 7 April 1907 in Varel, Oldenburg, Germany. His father was a doctor and his mother a Swedish gymnastic director.


Pre-World War II years


World War II Era

More detail about aspects of Wegener's biography during the Nazi regime first became available in 2006. Wegener joined the
Nazi Party The Nazi Party, officially the National Socialist German Workers' Party (german: Nationalsozialistische Deutsche Arbeiterpartei or NSDAP), was a far-right politics, far-right political party in Germany active between 1920 and 1945 that crea ...
in 1932. Specifically, he was a member of the
Sturmabteilung The (; SA; literally "Storm Detachment") was the original paramilitary wing of the Nazi Party. It played a significant role in Adolf Hitler's rise to power in the 1920s and 1930s. Its primary purposes were providing protection for Nazi ral ...
, a paramilitary branch of the Nazi party which participated in violent conflicts. As a relatively high-ranking military physician, he spent some of
World War II World War II or the Second World War, often abbreviated as WWII or WW2, was a world war that lasted from 1939 to 1945. It involved the vast majority of the world's countries—including all of the great powers—forming two opposin ...
in a medical office three blocks from the
Łódź Ghetto The Łódź Ghetto or Litzmannstadt Ghetto (after the Nazi German name for Łódź) was a Nazi ghetto established by the German authorities for Polish Jews and Roma following the Invasion of Poland. It was the second-largest ghetto in all of Ge ...
, a
Jewish ghetto In the Jewish diaspora, a Jewish quarter (also known as jewry, ''juiverie'', ''Judengasse'', Jewynstreet, Jewtown, or proto-ghetto) is the area of a city traditionally inhabited by Jews. Jewish quarters, like the Jewish ghettos in Europe, were ...
in
Łódź Łódź, also rendered in English as Lodz, is a city in central Poland and a former industrial centre. It is the capital of Łódź Voivodeship, and is located approximately south-west of Warsaw. The city's coat of arms is an example of canti ...
,
Poland Poland, officially the Republic of Poland, is a country in Central Europe. It is divided into 16 administrative provinces called voivodeships, covering an area of . Poland has a population of over 38 million and is the fifth-most populous ...
. He conducted
autopsies An autopsy (post-mortem examination, obduction, necropsy, or autopsia cadaverum) is a surgical procedure that consists of a thorough examination of a corpse by dissection to determine the cause, mode, and manner of death or to evaluate any d ...
on
Jewish Jews ( he, יְהוּדִים, , ) or Jewish people are an ethnoreligious group and nation originating from the Israelites Israelite origins and kingdom: "The first act in the long drama of Jewish history is the age of the Israelites""The ...
concentration camp Internment is the imprisonment of people, commonly in large groups, without charges or intent to file charges. The term is especially used for the confinement "of enemy citizens in wartime or of terrorism suspects". Thus, while it can simply ...
inmates and the facility he worked in performed experiments on prisoners. There is no direct evidence of active participation of Wegener in these human experiments, but it is likely he was aware of them. The
United Nations War Crimes Commission The United Nations War Crimes Commission (UNWCC) initially called the United Nations Commission for the Investigation of War Crimes, was a commission of the United Nations that investigated allegations of war crimes committed by Nazi Germany and ...
had a legal mandate against Friedrich Wegener and the Polish Institute for the Prosecution of German War Crimes confirmed that he had appeared on the central list of war criminal and security suspects. Wegener was released without a trial as no charges were brought against him. In an editorial in 2006 the evidence was regarded as “thin but tangible."


Medical contributions

In 1936, Friedrich Wegener described the disease that once bore his name, Wegener disease, as systemic disorder characterized by aseptic vasculitis granulomatous inflammation and vasculitis which affects the upper and lower respiratory tracts and the kidneys. Granulomatosis with Polyangiitis is a relatively rare disorder, occurring in 1/25,000 persons.Non-neoplastic Disorders of the Lower Respiratory Tract. by William D Travis. Publisher: Washington, DC American Registry of Pathology 2002 After revelations about his Nazi Party past became common knowledge, the disease has been referred to as Granulomatosis with Polyangiitis (GPA). The American College of Chest Physicians (ACCP) awarded Wegener a “master clinician” prize in 1989. After his Nazi past was discovered in 2000, the ACCP rescinded the prize and campaigned to rename Wegener's granulomatosis to ANCA-associated granulomatous vasculitis. More recently, several professional societies, including the
American College of Rheumatology The American College of Rheumatology (ACR; until 1985 called American Rheumatism Association) is an organization of and for physicians, health professionals, and scientists that advances rheumatology through programs of education, research, advocacy ...
, the
European League Against Rheumatism The European Alliance of Associations for Rheumatology (EULAR) formerly the European League Against Rheumatism is a European non-governmental organization which represents the people with arthritis/rheumatism, health professional and scientific so ...
, and the
American Society of Nephrology Founded in 1966, the American Society of Nephrology (ASN) is the world's largest professional society devoted to the study of kidney disease. Composed of over 20,000 physicians and scientists, ASN promotes expert patient care, advances medical ...
, proposed the name 'granulomatosis with polyangiitis' in a 2011 editorial. The new name for the condition is now widely adopted in the scientific literature and by institutions and charities.


See also

*
List of medical eponyms with Nazi associations This article lists medical eponyms which have been associated with Nazi human experimentation or Nazi politics. While normally eponyms used in medicine serve to honor the memory of the physician or researcher who first documented a disease or pione ...


References


Further reading

* * * Grzybowski A, Rohrbach JM (2011)Should we abandon the eponym 'Wegener's granulomatosis'? A historical excursion (Letter to the editor). Retina 31, 1439-1442 {{DEFAULTSORT:Wegener, Friedrich 1907 births 1990 deaths People from Varel People from the Grand Duchy of Oldenburg German pathologists Physicians in the Nazi Party Academic staff of the University of Kiel