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In 2014, Ebola virus disease in Spain occurred due to two patients with cases of the disease contracted during the
Ebola virus epidemic in West Africa The 2013–2016 epidemic of Ebola virus disease, centered in Western Africa, was the most widespread outbreak of the disease in history. It caused major loss of life and socioeconomic disruption in the region, mainly in Guinea, Liberia and S ...
; they were medically evacuated. A failure in infection control in the treatment of the second patient led to an isolated infection of Ebola virus disease in a health worker in Spain itself. The health worker survived her Ebola infection, and has since been declared infection-free.


Initial medevac cases

On 5 August 2014, the
Brothers Hospitallers of St. John of God The Brothers Hospitallers of Saint John of God, officially the Hospitaller Order of the Brothers of Saint John of God (abbreviated as O.H.), are a Catholic religious order founded in 1572. In Italian they are also known commonly as the Fatebenef ...
confirmed that Brother Miguel Pajares, who had been volunteering in Liberia, had become infected. He was evacuated to Spain on 6 August 2014, and subsequently died on 12 August. On 21 September it was announced that Brother Manuel García Viejo, another Spanish citizen who was medical director at the
St John of God Hospital Sierra Leone St. John of God Catholic Hospital, also known as Mabessaneh Hospital, is a hospital located in Mabesseneh, Lunsar, Sierra Leone. It is run by the Brothers Hospitallers of St. John of God, an international Catholic organisation. It is a non-den ...
in
Lunsar Lunsar is a town in Marampa Chiefdom, Port Loko District in the Northern Province of Sierra Leone. It is the largest town in Port Loko District by population. The Britannica estimate of the population of Lunsar is 36,1 The town is one of the main ...
, had been evacuated to Spain from Sierra Leone after being infected with the virus. His death was announced on 25 September. Both of these cases were treated at the
Hospital Carlos III The Hospital Carlos III is a public hospital in the city of Madrid. It belongs to the ''Servicio Madrileño de Salud'', the health service of the Community of Madrid. It was crested in 1990 from the merger of three previous hospitals, and was esta ...
in Madrid.


Medical personnel infection

In October 2014, María Teresa Romero Ramos, an
auxiliary nurse Nursing in the United Kingdom has a long history. The current form of nursing is often considered as beginning with Florence Nightingale who pioneered modern nursing. Nightingale initiated formal schools of nursing in the United Kingdom in the l ...
who had cared for Manuel García Viejo at the Hospital Carlos III had become unwell and on 6 October tested positive for Ebola at her local hospital in Alcorcón, the
Hospital Universitario Fundación Alcorcón The Hospital Universitario Fundación Alcorcón (HUFA) is a major general hospital in Alcorcón, a city in the Madrid metropolitan area of Spain. It was founded in 1997. Although the hospital was built by the Spanish National Health System, its m ...
. A second test confirmed the diagnosis, making this the first confirmed case of Ebola transmission outside Africa. Following testing, she was transferred to the
Hospital Carlos III The Hospital Carlos III is a public hospital in the city of Madrid. It belongs to the ''Servicio Madrileño de Salud'', the health service of the Community of Madrid. It was crested in 1990 from the merger of three previous hospitals, and was esta ...
in Madrid for treatment. As of October 7, 50 contacts were being monitored, with 7 kept in isolation at the Hospital Carlos III, and an investigation was under way. On 7 October, Madrid's regional government got a court order to euthanize Romero's pet dog, Excalibur, concerned that it posed a risk as a reservoir host. By the afternoon there were over 30 animal rights activists who had barricaded the apartment to prevent officials from removing the dog. A number of online petitions were started rallying to save the dog, garnering hundreds of thousands of indications of support. Ramos' quarantined husband, Javier, called on a veterinarian radio show host, and recorded a video appeal, for help to save his dog. On 8 October, Spanish authorities removed, sedated and euthanized the dog and arranged for the safe disposal of its remains. On 9 October the Spanish health ministry quarantined three more people. The health authorities announced that María Teresa Romero Ramos' condition had worsened significantly. On October 12, she began to show some improvement. According to one report, the improvement may be attributed to Romero's having received the experimental drug ZMab which is similar to
ZMapp ZMapp is an experimental biopharmaceutical drug comprising three chimeric monoclonal antibodies under development as a treatment for Ebola virus disease. Two of the three components were originally developed at the Public Health Agency of Canada ...
, which has been used to treat several Ebola patients. However, according to information released by Spain's Centre for Health and Emergency Alerts, the nurse did not receive ZMab due to concerns over possible side-effects. Romero, however, was given the experimental antiviral drug Favipiravir, and it was reported that the dosages used were much higher than those used in the treatment of other patients. Medical staff in Madrid protested about the lack of effective protective equipment and safety precautions. It was reported on October 17 that all the other people suspected of being infected in Spain had tested negative for the Ebola virus. On October 20 it was announced that Teresa Romero had tested negative for the Ebola virus, suggesting she may have cleared the virus from her system. On November 1, it was announced that she was Ebola-free, and had been moved out of the isolation ward into a normal hospital bed to finish the process of recuperation from her illness. The WHO declared Spain Ebola-free on 2 December, 42 days after Teresa Romero was shown to be free of Ebola on 21 October.


2018 prototype vaccine

In July 2018, a Spanish team from the October 12 Hospital in
Madrid Madrid ( , ) is the capital and most populous city of Spain. The city has almost 3.4 million inhabitants and a Madrid metropolitan area, metropolitan area population of approximately 6.7 million. It is the Largest cities of the Europ ...
announced the discovery of an
antibody An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein used by the immune system to identify and neutralize foreign objects such as pathogenic bacteria and viruses. The antibody recognizes a unique molecule of the ...
and the development of a prototype vaccine against five strains of Ebola, including the most common and deadliest.


Legacy in the 2020 coronavirus pandemic

The Ebola cases in Spain occurred when the country was governed by the People's Party, under prime minister
Mariano Rajoy Mariano Rajoy Brey (; born 27 March 1955) is a Spanish politician who served as Prime Minister of Spain from 2011 to 2018, when a vote of no confidence ousted his government. On 5 June 2018, he announced his resignation as People's Party lead ...
. The opposition
Spanish Socialist Workers' Party The Spanish Socialist Workers' Party ( es, Partido Socialista Obrero Español ; PSOE ) is a social-democraticThe PSOE is described as a social-democratic party by numerous sources: * * * * political party in Spain. The PSOE has been in gove ...
(PSOE) used its official Twitter account to directly blame Rajoy for the outbreak, and party leader
Pedro Sánchez Pedro Sánchez Pérez-Castejón (; born 29 February 1972) is a Spanish politician who has been Prime Minister of Spain since June 2018. He has also been Secretary-General of the Spanish Socialist Workers' Party (PSOE) since June 2017, having pr ...
called the government a "disgovernment" while calling for the dismissal of Health Minister
Ana Mato Ana Mato Adrover (born 24 September 1959 in Madrid) is a Spanish politician. From 2011 to 2014 she served as Spain's Minister of Health, Social Services and Equality in the Rajoy Cabinet. On 26 November 2014 she resigned due to the involvement o ...
. Pablo Iglesias, leader of the left-wing party Podemos also blamed the government for the outbreak. These comments received scrutiny during the
COVID-19 pandemic in Spain The COVID-19 pandemic in Spain has resulted in confirmed cases of COVID-19 and deaths. The virus was first confirmed to have spread to Spain on 31 January 2020, when a German tourist tested positive for SARS-CoV-2 in La Gomera, Canary Island ...
in which tens of thousands of people were infected and thousands died, while Sánchez was prime minister and Iglesias deputy prime minister.


References


Further reading

* {{Europe topic , Ebola virus disease in
Spain , image_flag = Bandera de España.svg , image_coat = Escudo de España (mazonado).svg , national_motto = ''Plus ultra'' (Latin)(English: "Further Beyond") , national_anthem = (English: "Royal March") , i ...
Disease outbreaks in Spain 2014 in Spain Ebola