In
cardiovascular physiology Cardiovascular physiology is the study of the cardiovascular system, specifically addressing the physiology of the heart ("cardio") and blood vessels ("vascular").
These subjects are sometimes addressed separately, under the names cardiac physiolog ...
, end-diastolic volume (EDV) is the volume of blood in the right or left ventricle at end of filling in
diastole
Diastole ( ) is the relaxed phase of the cardiac cycle when the chambers of the heart are re-filling with blood. The contrasting phase is systole when the heart chambers are contracting. Atrial diastole is the relaxing of the atria, and ventric ...
which is ammount of blood present in ventricle at the end of diastole
systole
Systole ( ) is the part of the cardiac cycle during which some chambers of the heart contract after refilling with blood. The term originates, via New Latin, from Ancient Greek (''sustolē''), from (''sustéllein'' 'to contract'; from ''sun ...
.
Because greater EDVs cause greater distention of the ventricle, ''EDV'' is often used synonymously with ''
preload
Preload may refer to:
Science and technology
* Preload (cardiology), maximum stretch of the heart at the end of diastole
* preload (software), code-prefetching software for Linux
* Preload (engineering), the internal application of stress to cert ...
'', which refers to the length of the
sarcomere
A sarcomere (Greek σάρξ ''sarx'' "flesh", μέρος ''meros'' "part") is the smallest functional unit of striated muscle tissue. It is the repeating unit between two Z-lines. Skeletal muscles are composed of tubular muscle cells (called musc ...
s in
cardiac muscle
Cardiac muscle (also called heart muscle, myocardium, cardiomyocytes and cardiac myocytes) is one of three types of vertebrate muscle tissues, with the other two being skeletal muscle and smooth muscle. It is an involuntary, striated muscle th ...
prior to contraction (systole). An increase in EDV increases the preload on the heart and, through the
Frank-Starling mechanism of the heart, increases the amount of blood ejected from the ventricle during systole (
stroke volume
In cardiovascular physiology, stroke volume (SV) is the volume of blood pumped from the left ventricle per beat. Stroke volume is calculated using measurements of ventricle volumes from an echocardiogram and subtracting the volume of the blood i ...
).
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Sample values
The right ventricular end-diastolic volume (RVEDV) ranges between 100 and 160 mL.
The right ventricular end-diastolic volume index (RVEDVI) is calculated by RVEDV/
BSA and ranges between 60 and 100 mL/m
2.
[
]
See also
* End-systolic volume
End-systolic volume (ESV) is the volume of blood in a ventricle at the end of contraction, or systole, and the beginning of filling, or diastole.
ESV is the lowest volume of blood in the ventricle at any point in the cardiac cycle.
The main facto ...
* Stroke volume
In cardiovascular physiology, stroke volume (SV) is the volume of blood pumped from the left ventricle per beat. Stroke volume is calculated using measurements of ventricle volumes from an echocardiogram and subtracting the volume of the blood i ...
References
{{DEFAULTSORT:End-Diastolic Volume
Cardiovascular physiology