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''Grona triflora'', known as creeping tick trefoil or three-flower beggarweed, is a plant in the family
Fabaceae The Fabaceae or Leguminosae,International Code of Nomenc ...
. It is native to tropical regions around the globe and introduced to subtropical regions including the southern United States. File:Desmodium triflorum in Kadavoor.jpg, Foliage File:Desmodium triflorum fruit and seeds.jpg, Fruit and seeds File:Desmodium triflorum at Peradeniya Royal Botanical Garden.jpg, At Peradeniya Royal Botanical Garden


Phytochemicals

''Grona triflora'' (''Desmodium triflorum'') contains alkaloids including ''N'',''N''-dimethyl
tryptophan Tryptophan (symbol Trp or W) is an α-amino acid that is used in the biosynthesis of proteins. Tryptophan contains an α-amino group, an α- carboxylic acid group, and a side chain indole, making it a polar molecule with a non-polar aromatic ...
methyl ester, dimethyltryptamine-''N''-oxide, hypaphorine (structurally related to
plakohypaphorine Plakohypaphorines are halogenated indolic non-proteinogenic amino acids named for their similarity to hypaphorine (''N,N,N''-trimethyltryptophan). First reported in the Caribbean sponge Sponges, the members of the phylum Porifera (; meaning ...
),
phenylethylamine Phenethylamine (PEA) is an organic compound, natural monoamine alkaloid, and trace amine, which acts as a central nervous system stimulant in humans. In the brain, phenethylamine regulates monoamine neurotransmission by binding to trace amin ...
,
hordenine Hordenine is an alkaloid of the phenethylamine class that occurs naturally in a variety of plants, taking its name from one of the most common, barley (''Hordeum'' species). Chemically, hordenine is the ''N''-methyl derivative (chemistry), derivat ...
,
tyramine Tyramine ( ) (also spelled tyramin), also known under several other names, is a naturally occurring trace amine derived from the amino acid tyrosine. Tyramine acts as a catecholamine releasing agent. Notably, it is unable to cross the blood-b ...
, and
trigonelline Trigonelline is an alkaloid with chemical formula . It is a zwitterion formed by the methylation of the nitrogen atom of niacin (vitamin B3). Trigonelline is a product of niacin metabolism that is excreted in urine of mammals. Trigonelline occurs ...
.


Medicinal applications and qualities

Creeping tick trefoil has been utilized in folk medicine. Conditions it has been used for include wounds, diarrhea, rheumatism, dysentery, and skin diseases. Known substances found in trefoils include alkaloids and flavonoids. The entire plant is used in human nutritional treatment.Herbpathy https://herbpathy.com/Uses-and-Benefits-of-Creeping-Tick-Trefoil-Cid1166 retrieved 17 Oct 2022


Agricultural applications

Creeping tick trefoil is used in agriculture similarly to the closely related ''Desmodium''; see Desmodium#uses.


References

triflora {{Faboideae-stub