Derek Lowe is a
medicinal chemist working on preclinical
drug discovery
In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered.
Historically, drugs were discovered by identifying the active ingredient from traditional remedies or by ...
in the pharmaceutical industry. Lowe has published a blog about this field, "In the Pipeline", since 2002 and is a columnist for the
Royal Society of Chemistry
The Royal Society of Chemistry (RSC) is a learned society (professional association) in the United Kingdom with the goal of "advancing the chemistry, chemical sciences". It was formed in 1980 from the amalgamation of the Chemical Society, the Ro ...
's ''
Chemistry World''.
Biography
Lowe (born in
Harrisburg, Arkansas
Harrisburg is a city in Poinsett County, Arkansas, United States. The population was 2,288 at the 2010 census. It is included in the Jonesboro, Arkansas Metropolitan Statistical Area. The city is the county seat of Poinsett County.
Geography
H ...
) got his BA from
Hendrix College
Hendrix College is a private liberal arts college in Conway, Arkansas. Approximately 1,000 students are enrolled, mostly undergraduates. While affiliated with the United Methodist Church, the college offers a secular curriculum and has a studen ...
and his PhD in
organic chemistry
Organic chemistry is a subdiscipline within chemistry involving the science, scientific study of the structure, properties, and reactions of organic compounds and organic materials, i.e., matter in its various forms that contain carbon atoms.Clay ...
from
Duke University on synthesis of natural products, before spending time in
Germany
Germany, officially the Federal Republic of Germany (FRG),, is a country in Central Europe. It is the most populous member state of the European Union. Germany lies between the Baltic and North Sea to the north and the Alps to the sou ...
on a
Humboldt Fellowship.
[
Lowe was the one of the first people to blog from inside the pharmaceutical industry, with the approval of his supervisor and the company legal department, and one of the first science bloggers. By 2006, his blog had between 3,000 and 4,000 visitors per day during the workweek; he covered business matters, trends and issues in medicinal chemistry, and legal matters like patent law and regulation.]hit to lead
Hit to lead (H2L) also known as lead generation is a stage in early drug discovery where small molecule hits from a high throughput screen (HTS) are evaluated and undergo limited optimization to identify promising lead compounds. These lead comp ...
medical chemistry work.[ his blog received between 15,000 and 20,000 page views on a typical weekday.]BuzzFeed
BuzzFeed, Inc. is an American Internet media, news and entertainment company with a focus on digital media. Based in New York City, BuzzFeed was founded in 2006 by Jonah Peretti and John S. Johnson III to focus on tracking viral content. ...
that propagated chemophobia was widely cited.
He serves on the editorial board of ''ACS Medicinal Chemistry Letters
''ACS Medicinal Chemistry Letters'' is a monthly peer-reviewed scientific journal covering medicinal chemistry. It was established in 2009 and is published by the American Chemical Society. The editor-in-chief is Dennis C. Liotta (Emory University) ...
'' and on the advisory board of ''Chemical & Engineering News
''Chemical & Engineering News'' (''C&EN'') is a weekly news magazine published by the American Chemical Society, providing professional and technical news and analysis in the fields of chemistry and chemical engineering.[Novartis
Novartis AG is a Swiss-American multinational pharmaceutical corporation based in Basel, Switzerland and
Cambridge, Massachusetts, United States (global research).name="novartis.com">https://www.novartis.com/research-development/research-loc ...]
; formerly he had worked for 10 years at Vertex
Vertex, vertices or vertexes may refer to:
Science and technology Mathematics and computer science
*Vertex (geometry), a point where two or more curves, lines, or edges meet
*Vertex (computer graphics), a data structure that describes the position ...
, 9 years at Bayer
Bayer AG (, commonly pronounced ; ) is a German multinational pharmaceutical and biotechnology company and one of the largest pharmaceutical companies in the world. Headquartered in Leverkusen, Bayer's areas of business include pharmaceutica ...
, and 8 years at Schering-Plough
Schering-Plough Corporation was an American pharmaceutical company. It was originally the U.S. subsidiary of the German company Schering AG, which was founded in 1851 by Ernst Christian Friedrich Schering. As a result of nationalization, it bec ...
.
Notable publications
Book
*
Selected scientific papers
*
*
*
*
Selected blogs or commentary
* (1st post)
*
* Cited in
*
* ,
*
*
*
References
External links
*Lowe's
In the Pipeline
blog
Columns
at '' Chemistry World''
*
*
Reddit AMA
28 February 2014
Science blogs
21st-century American chemists
Drug discovery
Hendrix College alumni
Duke University alumni
Living people
People from Harrisburg, Arkansas
Year of birth missing (living people)
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