Derek Lowe is a
medicinal chemist
Medicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacy involved with designing and developing pharmaceutical drugs. Medicinal chemistry involves the identification, synthesis and developme ...
working on preclinical
drug discovery in the pharmaceutical industry. Lowe has published a blog about this field, "In the Pipeline", since 2002 and is a columnist for the
Royal Society of Chemistry
The Royal Society of Chemistry (RSC) is a learned society (professional association) in the United Kingdom with the goal of "advancing the chemical sciences". It was formed in 1980 from the amalgamation of the Chemical Society, the Royal Instit ...
's ''
Chemistry World''.
Biography
Lowe (born in
Harrisburg, Arkansas) got his BA from
Hendrix College
Hendrix College is a private liberal arts college in Conway, Arkansas. Approximately 1,000 students are enrolled, mostly undergraduates. While affiliated with the United Methodist Church, the college offers a secular curriculum and has a student ...
and his PhD in
organic chemistry
Organic chemistry is a subdiscipline within chemistry involving the scientific study of the structure, properties, and reactions of organic compounds and organic materials, i.e., matter in its various forms that contain carbon atoms.Clayden, ...
from
Duke University on synthesis of natural products, before spending time in
Germany
Germany,, officially the Federal Republic of Germany, is a country in Central Europe. It is the second most populous country in Europe after Russia, and the most populous member state of the European Union. Germany is situated betwe ...
on a
Humboldt Fellowship
The Alexander von Humboldt Foundation (german: Alexander von Humboldt-Stiftung) is a foundation established by the government of the Federal Republic of Germany and funded by the Federal Foreign Office, the Federal Ministry of Education and Resear ...
.
[
Lowe was the one of the first people to blog from inside the pharmaceutical industry, with the approval of his supervisor and the company legal department, and one of the first science bloggers. By 2006, his blog had between 3,000 and 4,000 visitors per day during the workweek; he covered business matters, trends and issues in medicinal chemistry, and legal matters like patent law and regulation.]hit to lead
Hit to lead (H2L) also known as lead generation is a stage in early drug discovery where small molecule hits from a high-throughput screening, high throughput screen (HTS) are evaluated and undergo limited optimization to identify promising lead co ...
medical chemistry work.[ his blog received between 15,000 and 20,000 page views on a typical weekday.]chemophobia
Chemophobia (or chemphobia or chemonoia) is an aversion to or prejudice against chemicals or chemistry. The phenomenon has been ascribed both to a reasonable concern over the potential adverse effects of synthetic chemicals, and to an irrational f ...
was widely cited.
He serves on the editorial board of '' ACS Medicinal Chemistry Letters'' and on the advisory board of ''Chemical & Engineering News
''Chemical & Engineering News'' (''C&EN'') is a weekly news magazine published by the American Chemical Society, providing professional and technical news and analysis in the fields of chemistry and chemical engineering.[Novartis
Novartis AG is a Swiss-American multinational pharmaceutical corporation based in Basel, Switzerland and
Cambridge, Massachusetts, United States (global research).name="novartis.com">https://www.novartis.com/research-development/research-loc ...]
; formerly he had worked for 10 years at Vertex
Vertex, vertices or vertexes may refer to:
Science and technology Mathematics and computer science
*Vertex (geometry), a point where two or more curves, lines, or edges meet
* Vertex (computer graphics), a data structure that describes the positio ...
, 9 years at Bayer, and 8 years at Schering-Plough
Schering-Plough Corporation was an American pharmaceutical company. It was originally the U.S. subsidiary of the German company Schering AG, which was founded in 1851 by Ernst Christian Friedrich Schering. As a result of nationalization, it beca ...
.
Notable publications
Book
*
Selected scientific papers
*
*
*
*
Selected blogs or commentary
* (1st post)
*
* Cited in
*
* ,
*
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*
References
External links
*Lowe's
In the Pipeline
blog
Columns
at '' Chemistry World''
*
*
Reddit AMA
28 February 2014
Science blogs
21st-century American chemists
Drug discovery
Hendrix College alumni
Duke University alumni
Living people
People from Harrisburg, Arkansas
Year of birth missing (living people)
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