Daniel Carlat is an American
psychiatrist known for his critical stance towards pharmaceutical prescription practices and corporate sponsorship of
continuing medical education.
He is the CEO of Carlat Publishing, which sells newsletters and other materials used for CME.
Background
Currently, Carlat is a faculty member at Tufts Medical School and serves as the editor of ''The'' ''Carlat Psychiatry Report,'' a monthly newsletter.
In 2007, he wrote a ''New York Times Magazine'' article entitled "Dr. Drug Rep" about how he was recruited by the pharmaceutical company
Wyeth
Wyeth, LLC was an American pharmaceutical company. The company was founded in Philadelphia, Pennsylvania, in 1860 as ''John Wyeth and Brother''. It was later known, in the early 1930s, as American Home Products, before being renamed to Wyeth in ...
to promote the
antidepressant Effexor
Venlafaxine, sold under the brand name Effexor among others, is an antidepressant medication of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. It is used to treat major depressive disorder, generalized anxiety disorder, panic di ...
as being more effective than other antidepressants on the market. According to Carlat, he began to doubt the quality of the data that supported the drug he was paid to promote, pointing towards the short-term nature of the studies cited by the company, along with concerns raised about withdrawal symptoms. He eventually chose to quit giving talks on behalf of drug companies entirely after being questioned by a Wyeth district manager about his "enthusiasm" for the product''.''
In another 2007 article in The Boston Globe, he criticized
Massachusetts General Hospital for accepting millions of dollars from drug companies that sponsored continuing psychiatry courses.
Carlat has also criticized the quality of psychiatric
pathophysiology by comparing his field to
cardiology
Cardiology () is a branch of medicine that deals with disorders of the heart and the cardiovascular system. The field includes medical diagnosis and treatment of congenital heart defects, coronary artery disease, heart failure, valvular h ...
, which he argues has a better understanding of how to treat problems using medication. He cites problems such as an inability to directly measure
neurotransmitter levels in living patients and a reliance on indirect testing methods (e.g., measuring
serotonin based on
cerebrospinal fluid
Cerebrospinal fluid (CSF) is a clear, colorless body fluid found within the tissue that surrounds the brain and spinal cord of all vertebrates.
CSF is produced by specialised ependymal cells in the choroid plexus of the ventricles of the ...
samples or during
post-mortem
An autopsy (post-mortem examination, obduction, necropsy, or autopsia cadaverum) is a surgical procedure that consists of a thorough examination of a corpse by dissection to determine the cause, mode, and manner of death or to evaluate any di ...
studies).
References
{{DEFAULTSORT:Carlat, Daniel
Living people
American psychiatrists
University of California, San Francisco alumni
Year of birth missing (living people)