Daf-5 is an
ortholog of the mammalian
protein Sno/Ski，which present in the nematode worm ''
Caenorhabditis elegans
''Caenorhabditis elegans'' () is a free-living transparent nematode about 1 mm in length that lives in temperate soil environments. It is the type species of its genus. The name is a blend of the Greek ''caeno-'' (recent), ''rhabditis'' (ro ...
'' on the downstream of
TGFβ signaling pathway
The transforming growth factor beta (TGFB) signaling pathway is involved in many cellular processes in both the adult organism and the developing embryo including cell growth, cell differentiation, cell migration, apoptosis, cellular homeostasi ...
. Without
daf-7 signal, daf-5 combined with
daf-3,
co-SMAD for ''C. elegans'', to form a heterodimer and started dauer development.
References
Caenorhabditis elegans genes
{{Gene-stub