Clinodactyly is a medical term describing the curvature of a

digit Digit may refer to: Mathematics and science * Numerical digit, as used in mathematics or computer science ** Hindu-Arabic numerals, the most common modern representation of numerical digits * Digit (anatomy), the most distal part of a limb, such ...

(a finger or toe) in the plane of the palm, most commonly the fifth finger (the " little finger") towards the adjacent fourth finger (the " ring finger"). It is a fairly common isolated anomaly which often goes unnoticed, but also occurs in combination with other abnormalities in certain genetic syndromes. The term is from the Ancient Greek κλίνειν ' 'to bend' and δάκτυλος ' 'digit'.

Genetics

Clinodactyly is an autosomal dominant trait that has variable expressiveness and incomplete penetrance. Clinodactyly can be passed through inheritance and presents as either an isolated anomaly or a component manifestation of a genetic syndrome. Many syndromes are associated with clinodactyly, including those listed below. But the phenotype, by itself, is not a sensitive or specific diagnostic test for these syndromes (it is present in up to 18% of the normal population). * Down syndrome * Turner syndrome * Aarskog syndrome * Carpenter syndrome * Seckel syndrome * Cornelia de Lange syndrome * Orofaciodigital syndrome 1 *

13q deletion syndrome 13q deletion syndrome is a rare genetic disease caused by the deletion of some or all of the large arm of human chromosome 13. Depending upon the size and location of the deletion on chromosome 13, the physical and mental manifestations will vary. ...

* XXYY syndrome * Silver–Russell syndrome * Andersen-Tawil syndrome * Noonan syndrome * Ehlers–Danlos syndrome When identified prenatally, ''in conjunction with other features'' of Down syndrome, for example during obstetric ultrasonography, it may be an indication for intrauterine sampling for fetal chromosome analysis.

Pathophysiology

Due to a developmental arrest, there is an abnormal alignment of the joint surfaces at either interphalangeal joint causing angulation in the plane of the palm. The finger may be slightly bent or have a very prominent bend.

Diagnosis

There is no consensus on what degree of angulation justifies a diagnosis; an incline between 15° and 30° is typical. A similar-sounding term, camptodactyly, is a fixed flexion deformity of a digit.

Management

Treatment is only necessary if the degree of curvature is sufficient to cause disability or if it causes emotional distress. Splinting does not routinely correct the deformity. Surgical treatments are closing wedge osteotomy, opening wedge osteotomy, and reversed wedge osteotomy. Radiographs of the fingers are useful in planning the surgical procedure. Severe clinodactyly may require soft tissue alterations to the digit such as release of skin, extensor tendon relocation, and collateral ligament advancement.

Epidemiology

Minor degrees of curvature are common. Reports of incidence vary between 1% and 19.5%.

References

External links

{{Congenital malformations and deformations of musculoskeletal system Human genetics Congenital disorders of musculoskeletal system