Cephalometry
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Cephalometry is the study and measurement of the
head A head is the part of an organism which usually includes the ears, brain, forehead, cheeks, chin, eyes, nose, and mouth, each of which aid in various sensory functions such as sight, hearing, smell, and taste. Some very simple animals may ...
, usually the
human head In human anatomy, the head is at the top of the human body. It supports the face and is maintained by the skull, which itself encloses the brain. Structure The human head consists of a fleshy outer portion, which surrounds the bony skull. T ...
, especially by
medical imaging Medical imaging is the technique and process of imaging the interior of a body for clinical analysis and medical intervention, as well as visual representation of the function of some organs or tissues (physiology). Medical imaging seeks to rev ...
such as
radiography Radiography is an imaging technique using X-rays, gamma rays, or similar ionizing radiation and non-ionizing radiation to view the internal form of an object. Applications of radiography include medical radiography ("diagnostic" and "therapeut ...
.
Craniometry Craniometry is measurement of the cranium (the main part of the skull), usually the human cranium. It is a subset of cephalometry, measurement of the head, which in humans is a subset of anthropometry, measurement of the human body. It is disti ...
, the measurement of the cranium (
skull The skull is a bone protective cavity for the brain. The skull is composed of four types of bone i.e., cranial bones, facial bones, ear ossicles and hyoid bone. However two parts are more prominent: the cranium and the mandible. In humans, the ...
), is a large subset of cephalometry. Cephalometry also has a history in
phrenology Phrenology () is a pseudoscience which involves the measurement of bumps on the skull to predict mental traits.Wihe, J. V. (2002). "Science and Pseudoscience: A Primer in Critical Thinking." In ''Encyclopedia of Pseudoscience'', pp. 195–203. C ...
, which is the study of personality and character as well as
physiognomy Physiognomy (from the Greek , , meaning "nature", and , meaning "judge" or "interpreter") is the practice of assessing a person's character or personality from their outer appearance—especially the face. The term can also refer to the general ...
, which is the study of facial features. Cephalometry as applied in a
comparative anatomy Comparative anatomy is the study of similarities and differences in the anatomy of different species. It is closely related to evolutionary biology and phylogeny (the evolution of species). The science began in the classical era, continuing in t ...
context informs
biological anthropology Biological anthropology, also known as physical anthropology, is a scientific discipline concerned with the biological and behavioral aspects of human beings, their extinct hominin ancestors, and related non-human primates, particularly from an e ...
. In clinical contexts such as
dentistry Dentistry, also known as dental medicine and oral medicine, is the branch of medicine focused on the teeth, gums, and mouth. It consists of the study, diagnosis, prevention, management, and treatment of diseases, disorders, and conditions o ...
and oral and maxillofacial surgery,
cephalometric analysis Cephalometric analysis is the clinical application of cephalometry. It is analysis of the dental and skeletal relationships of a human skull. It is frequently used by dentists, orthodontists, and oral and maxillofacial surgeons as a treatment ...
helps in treatment and research; cephalometric landmarks guide surgeons in planning and operating.


History

The history of cephalometry ('' cephalo-'' + '' -metry'', "head measurement") can be traced through art, science, and anthropology. The origins of the important method of measuring has its origins in the Renaissance. Leonardo da Vinci is perhaps the most well known scientist and artist studying facial proportions during the Renaissance. Da Vinci along with others utilized grids to study the proportions of the face and make generalizations about them. Da Vinci looked for
divine proportions Divine Proportions (born 13 March 2002 in Kentucky) is a champion Thoroughbred race horse and winner of two French classics. Background Divine Proportions was bred by the Niarchos family. She was sired by the American-bred stallion Kingmambo. ...
in his quest to understand facial proportions. The divine proportion has since been found to exist in 20th centuries of facial proportions as they relate to esthetics. Beginning with Petrus Camper in the 18th century angles began to be employed in the measurement of facial form. Camper also began the practice of ethnographic grouping based on facial form. Anders Retzius defined the cephalic index and classified different shapes of the head. Brachycephalic refers to a small, rounded head. Dolichocephalic refers to a long head. Mesocephalic refers to a medium-sized head, typically between the brachycephalic and dolichocephalic sizes.


Timeline

*
Anders Retzius Anders Adolph Retzius (13 October 1796 – 18 April 1860), was a Swedish professor of anatomy and a supervisor at the Karolinska Institute in Stockholm. Biography Retzius was born in Lund, Sweden, in 1796. He enrolled at Lund University in 18 ...
(1796–1860) Defined the cephalic index as means to classify ancient human remains in Europe. * 1931, orthodontists consecrated the era of cephalometry. * 1960s began the era of computed cephalometric radiology. * 1961 Donald and Brown published an article about using ultrasounds for fetal head measurement correlation of diameter and fetal weight.


Applications


Dentistry

Cephalometric analysis Cephalometric analysis is the clinical application of cephalometry. It is analysis of the dental and skeletal relationships of a human skull. It is frequently used by dentists, orthodontists, and oral and maxillofacial surgeons as a treatment ...
is used in
dentistry Dentistry, also known as dental medicine and oral medicine, is the branch of medicine focused on the teeth, gums, and mouth. It consists of the study, diagnosis, prevention, management, and treatment of diseases, disorders, and conditions o ...
, and especially in
orthodontics Orthodontics is a dentistry specialty that addresses the diagnosis, prevention, management, and correction of mal-positioned teeth and jaws, and misaligned bite patterns. It may also address the modification of facial growth, known as dentofacial ...
, to gauge the size and spatial relationships of the
teeth A tooth ( : teeth) is a hard, calcified structure found in the jaws (or mouths) of many vertebrates and used to break down food. Some animals, particularly carnivores and omnivores, also use teeth to help with capturing or wounding prey, tear ...
,
jaw The jaw is any opposable articulated structure at the entrance of the mouth, typically used for grasping and manipulating food. The term ''jaws'' is also broadly applied to the whole of the structures constituting the vault of the mouth and serv ...
s, and
cranium The skull is a bone protective cavity for the brain. The skull is composed of four types of bone i.e., cranial bones, facial bones, ear ossicles and hyoid bone. However two parts are more prominent: the cranium and the mandible. In humans, the ...
. This analysis informs treatment planning, quantifies changes during treatment, and provides data for
clinical research Clinical research is a branch of healthcare science that determines the safety and effectiveness ( efficacy) of medications, devices, diagnostic products and treatment regimens intended for human use. These may be used for prevention, treatm ...
. Cephalometry focuses on linear and angular dimensions established by bone, teeth, and facial measurements. It has also been used for measurements of hard and soft tissues of the craniofacial complex.


Obstetrics

Ultrasound Ultrasound is sound waves with frequency, frequencies higher than the upper audible limit of human hearing range, hearing. Ultrasound is not different from "normal" (audible) sound in its physical properties, except that humans cannot hea ...
cephalometry is useful for determining baby growth
in utero ''In Utero'' is the third and final studio album by American rock band Nirvana. It was released on September 21, 1993, by DGC Records. After breaking into the mainstream with their second album, ''Nevermind'' (1991), Nirvana hired Steve Albini t ...
. Cephalometry can also determine if an unborn child will pass through the birth canal. Certain 3D imaging applications are now used in obstetric cephalometry. In 1961, Donald and Brown employed ultrasound technique for measurement of the fetal head. Other scientists tried the method and found that the ultrasound technique was 3mm different than the post-natal measurement with calipers. This method requires that the transponder be placed on the maternal abdomen over the area of the fetal head. The transponder is moved until a pair of echos are strong and equal. This indicates that the parietals are perpendicular to the transmitting beam. The distance of the reflections equal the biparietal diameter. From this, the size of the head and the fetal weight can be determined with incredible accuracy. The use of ultrasound cephalometry is meant to be used in addition to other radiographic techniques. Thus far, no ill effects have been reported to the fetus or the mother using the ultrasound fetal cephalometry.


Forensics

Cephalometry can be used to assist in forensic investigations. Researchers work to compile databases of population-level craniometric data. Due to variations in cranial measurements by population these types of databases can help assist investigators working in a known region. One such database was utilized to test whether craniometric measurements can be utilized to measure stature when only fragmentary remains are available. Researchers created a database cranial measurements utilizing cephalograms of Garo women living in Bangladesh. Head circumference, head length, facial height from '
nasion The nasion () is the most anterior point of the frontonasal suture that joins the nasal part of the frontal bone and the nasal bones. It marks the midpoint at the intersection of the frontonasal suture with the internasal suture joining the nasa ...
' to 'gnathion', bizygomatic breadth and stature were all measured and documented. The measurements of the women were placed into a database and then a normative value was given for each measurement within that population. Results indicated that the only head circumference was positively statistically correlated with stature. One way in which cephalograms can be utilized is for accurate age estimation but not for sex estimation. One study confirmed that the
mandibular ramus In anatomy, the mandible, lower jaw or jawbone is the largest, strongest and lowest bone in the human facial skeleton. It forms the lower jaw and holds the lower teeth in place. The mandible sits beneath the maxilla. It is the only movable bone ...
length is strongly related to chronological age and can be utilized to predict whether an individual is older than 18 years or older with a highly significant degree of accuracy (95% confidence interval). If the ramus length is 7.0 cm or more, then the individual has an 81.25% probability of being 18 years or older. Further, the study confirmed that there is not a strong degree of sexual dimorphism between mandibular ramus length until an individual reaches 16 years of age. The accuracy of predicting sex with mandibular ramus length is only 54% making it an unreliable indicator of sex in forensic contexts. The study also has impacts for providing age estimation of living people. This could be applicable in immigration, criminal and civil investigations, adoption of children, or old-age pension requests. The study utilized scanned cephalometric radiographs to conduct the study. Cephalometry remains to be the most popular and useful method for investigating the craniofacial skeletal morphology. Skull measurements are also important for facial reconstruction in cases of disputed identity. In the Punjab study, the mesocephalic was the most common craniotype followed by dolicocephalic in the tropical regions. The brachycephalic was more common in the temperate regions. Genetic and environmental factors have been suggested for the presence of variations in cephalic indices among population groups. Dietary habits have also been shown to modulate the craniofacial form of people. The data this study gathered is only valid for the adult population and may be useful in future forensic contexts.


Sleep apnea

An Asian study was performed on children ages 3–13 who had obstructive sleep apnea. The study concluded that four cephalometric anthropomorphic parameters were related to the apnea-hypopnea index. Three of which indicated the importance of hyoid position in pediatric sleep apnea. Future studies are needed in this area. A Scottish study used cephalometric radiographs in order to find cause of sleep apnea. This was performed on adult men and women and found that location of the hyoid also correlates with the obstructive sleep apnea/hypopnea syndrome (OSAHS). The longer the distance of the hyoid to the mandibular plane along with a shorter mandibular corpus showed significantly associated with OSAHS. Compared with a control group, those with OSAHS had the hyoid bone lower in relation to the mandibular plane. By using a cephalometric analysis program, a study was able to conclude that people with a reduced midface length and an inferiorly placed hyoid tend to have smaller airways which can lead to obstructive sleep apnea. Lateral cephalography is useful in analyzing skeletal and soft tissue characteristics. They recorded 22 measurements from the lateral cephalograms and craniometric landmarks were digitized. In other studies, differences in characteristics were noted in the sagittal and vertical planes of apnea sufferers versus the controls. This study did not find these differences between their groups. They did find that using cephalometry there is a difference in craniofacial morphology of persons with obstructive sleep apnea versus the healthy population. On recent open public competitions, machine learning and shape analysis algorithms demonstrated the mean error of 1.92 mm for automated landmarking and up to 93.2% of agreement between automated and manual cephalometry


Technology

Advances in technology have allowed scientists and anthropologists to utilize statistical programs in order to estimate ancestry of a skull by taking measurements of various craniometric points. CRANID is a statistical program that is used when the source of a cranium is of unknown origin. Cranial measurements are taken and entered into a worldwide craniometric database that is compared to other known cranial metrics. This information allows the user to be able to estimate ancestry in archaeological, forensic, and repatriation context. It has highest accuracy when sex is able to be determined. Dolphin Imaging Cephalometric and Tracing Software is a cephalometric analysis that can measure airway dimensions and dentofacial parameters. It has been used for studies in obstructive sleep apnea. As cephalometry become more digitized by using different programs and scanners, caution should be taken when interpreting data. Objects measured by computer assisted methods may not be an exact match of the original. Scanning and surface reconstruction can produce some data measurement uncertainty. There have been known cases of different software producing different data even when the same skull is used under the same conditions. Software packages, AMIRA and TIVMI, were used for surface reconstructions. The mean difference between measurements was lower for TIVMI. AMIRA can produce up to 4% error in known measurements and 5% in dry skull measurements. Error rates should be taken into consideration when using digitized software for this purpose.


Other applications of cephalometry

* Study and prediction of facial growth by overlaying older images to compare growth. ** Computer programs have been designed that are capable of utilizing lateral cephalograms and comparing them with growth algorithms to test the reliability of the algorithms. Significant results were found to be valid in utilizing Bolton and Ricketts grown algorithms within 1.5mm. Two-year predictions were the most valid. * Diagnostics of special pathologies * Diagnosis of craniofacial anomalies * Evaluation of nasopharyngeal passage


See also

*
Anthropometry Anthropometry () refers to the measurement of the human individual. An early tool of physical anthropology, it has been used for identification, for the purposes of understanding human physical variation, in paleoanthropology and in various atte ...
*
Cranial vault The cranial vault is the space in the skull within the neurocranium, occupied by the brain. Development In humans, the cranial vault is imperfectly composed in newborns, to allow the large human head to pass through the birth canal. During bir ...
*
Craniofacial anthropometry The history of anthropometry includes its use as an early tool of anthropology, use for identification, use for the purposes of understanding human physical variation in paleoanthropology and in various attempts to correlate physical with racial ...
*
Phrenology Phrenology () is a pseudoscience which involves the measurement of bumps on the skull to predict mental traits.Wihe, J. V. (2002). "Science and Pseudoscience: A Primer in Critical Thinking." In ''Encyclopedia of Pseudoscience'', pp. 195–203. C ...
* Robert M. Ricketts


Bibliography

*Harris, J E, et al. "A field method for the cephalometric x-ray study of skulls in early Nubian cemeteries." ''American Journal of Physical Anthropology'' 24, no. 2 (March 1966): 265–273. * *{{cite journal , vauthors=Littlefield TR, Kelly KM, Cherney JC, Beals SP, Pomatto JK , title=Development of a new three-dimensional cranial imaging system , journal=J Craniofac Surg , volume=15 , issue=1 , pages=175–81 , date=January 2004 , pmid=14704586 , doi=10.1097/00001665-200401000-00042, s2cid=20288713
MW DefinitionArchived
2009-10-31)


References

Medical imaging