Calcium citrate malate is a water-soluble calcium supplement. It is the calcium

salt Salt is a mineral composed primarily of sodium chloride (NaCl), a chemical compound belonging to the larger class of salts; salt in the form of a natural crystalline mineral is known as rock salt or halite. Salt is present in vast quant ...

citric acid Citric acid is an organic compound with the chemical formula HOC(CO2H)(CH2CO2H)2. It is a colorless weak organic acid. It occurs naturally in citrus fruits. In biochemistry, it is an intermediate in the citric acid cycle, which occurs in ...

and

malic acid Malic acid is an organic compound with the molecular formula . It is a dicarboxylic acid that is made by all living organisms, contributes to the sour taste of fruits, and is used as a food additive. Malic acid has two stereoisomeric forms ( ...

with variable composition. Calcium citrate malate's bioavailability stems from its water-solubility and its method of dissolution. When dissolved, it releases calcium ions and a

calcium citrate Calcium citrate is the calcium salt of citric acid. It is commonly used as a food additive ( E333), usually as a preservative, but sometimes for flavor. In this sense, it is similar to sodium citrate. Calcium citrate is also found in some di ...

complex. Calcium ions are absorbed directly into intestinal cells, and the citrate complex enters the body through paracellular absorption. Calcium citrate malate is similar to

calcium malate Calcium malate is a compound with formula Ca(C2H4O(COO)2). It is the calcium salt of malic acid Malic acid is an organic compound with the molecular formula . It is a dicarboxylic acid that is made by all living organisms, contributes to the ...

and other calcium salts. The

European Food Safety Authority The European Food Safety Authority (EFSA) is the agency of the European Union (EU) that provides independent scientific advice and communicates on existing and emerging risks associated with the food chain. EFSA was established in February 2002, ...

has concluded that calcium citrate malate is "slightly more bioavailable" than other forms of calcium supplementation.

References

{{reflist Citrates Calcium compounds Malates