R05C Expectorants, excluding combinations with cough suppressants

R05CA
Expectorant Mucoactive agents are a class of chemical agents that aid in the clearance of mucus or sputum from the upper and lower airways, including the lungs, bronchi, and trachea. Mucoactive drugs include expectorants, mucolytics, mucoregulators, and muco ...
s

:R05CA01

Tyloxapol Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type. It is used as a surfactant to aid liquefaction and removal of mucopurulent (containing mucus and pus) bronchopulmonary secretions, administered by inhalation through ...

:R05CA02

Potassium iodide Potassium iodide is a chemical compound, medication, and dietary supplement. It is a medication used for treating hyperthyroidism, in radiation emergencies, and for protecting the thyroid gland when certain types of radiopharmaceuticals are u ...

:R05CA03

Guaifenesin Guaifenesin, also known as glyceryl guaiacolate, is an expectorant medication that aids in the elimination of sputum from the respiratory tract. Chemically it is an ether of guaiacol and glycerine. It is often used in combination with other me ...

:R05CA04 Ipecacuanha :R05CA05 Altheae radix :R05CA06 Senega :R05CA07

Antimony pentasulfide Antimony pentasulfide is an inorganic compound of antimony and sulfur, also known as antimony red. It is a nonstoichiometric compound with a variable composition. Its structure is unknown. Commercial samples are usually contaminated with sulfur, w ...

:R05CA08

Creosote Creosote is a category of carbonaceous chemicals formed by the distillation of various tars and pyrolysis of plant-derived material, such as wood or fossil fuel. They are typically used as preservatives or antiseptics. Some creosote types were ...

:R05CA09 Guaiacolsulfonate :R05CA10 Combinations :R05CA11

Levoverbenone Levoverbenone is an expectorant. It is the L-isomer of verbenone Verbenone is a natural organic compound classified as a terpene that is found naturally in a variety of plants. The chemical has a pleasant characteristic odor. Besides being a ...

:R05CA12 Hederae helicis folium :R05CA13

Cineole Eucalyptol is a monoterpenoid. A colorless liquid, it is a bicyclic ether. Eucalyptol has a fresh mint-like smell and a spicy, cooling taste. It is insoluble in water, but miscible with organic solvents. Eucalyptol makes up ~70% - 90% of eucal ...

R05CB
Mucolytic Mucoactive agents are a class of chemical agents that aid in the clearance of mucus or sputum from the upper and lower airways, including the lungs, bronchi, and trachea. Mucoactive drugs include expectorants, mucolytics, mucoregulators, and muco ...
s

:R05CB01

Acetylcysteine Acetylcysteine, also known as ''N''-acetylcysteine (NAC), is a medication that is used to treat paracetamol overdose and to loosen thick mucus in individuals with chronic bronchopulmonary disorders like pneumonia and bronchitis. It has been used ...

:R05CB02

Bromhexine Bromhexine is a mucolytic drug used in the treatment of respiratory disorders associated with viscid or excessive mucus. It was developed in the research laboratory of Boehringer Ingelheim in the late 1950s as an active ingredient for pharmace ...

:R05CB03

Carbocisteine Carbocisteine, also called carbocysteine, is a mucolytic that reduces the viscosity of sputum and so can be used to help relieve the symptoms of chronic obstructive pulmonary disorder (COPD) and bronchiectasis by allowing the sufferer to bring u ...

:R05CB04 Eprazinone :R05CB05

Mesna Mesna, sold under the brand name Mesnex among others, is a medication used in those taking cyclophosphamide or ifosfamide to decrease the risk of bleeding from the bladder. It is used either by mouth or injection into a vein. Common side effec ...

:R05CB06

Ambroxol Ambroxol is a drug that breaks up phlegm, used in the treatment of respiratory diseases associated with viscid or excessive mucus. Ambroxol is often administered as an active ingredient in cough syrup. It was patented in 1966 and came into med ...

:R05CB07

Sobrerol Sobrerol is a mucolytic. History Sobrerol was discovered by Ascanio Sobrero as an oxidation product of terpenes. Later the oxidation and reduction reactions of chiral pinene lead also to several possible isomers of carvone Carvone is a member ...

:R05CB08 Domiodol :R05CB09 Letosteine :R05CB10 Combinations :R05CB11 Stepronin :R05CB13

Dornase alfa Dornase alfa (proprietary name Pulmozyme from Genentech) is a highly purified solution of recombinant human deoxyribonuclease I (rhDNase), an enzyme which selectively cleaves DNA. Dornase alfa hydrolyzes the DNA present in sputum/mucus of cy ...

( desoxyribonuclease) :R05CB14 Neltenexine :R05CB15

Erdosteine Erdosteine is a molecule with mucolytic activity. Structurally it is a thiol derivative characterized by the presence of two thiol groups. These two functional sulfhydryl groups contained in the molecule are released following first-pass metabo ...

:R05CB16

Mannitol Mannitol is a type of sugar alcohol used as a sweetener and medication. It is used as a low calorie sweetener as it is poorly absorbed by the intestines. As a medication, it is used to decrease pressure in the eyes, as in glaucoma, and to lo ...

:QR05CB90 Dembrexine hydrochloride

R05D
Cough suppressant Cold medicines are a group of medicinal, medications taken individually or in Combination drug, combination as a Symptomatic treatment, treatment for the symptoms of the common cold and similar conditions of the upper respiratory tract. The t ...
s, excluding combinations with expectorants

R05DA Opium alkaloids and derivatives

:R05DA01

Ethylmorphine Ethylmorphine (also known as codethyline, dionine, and ethyl morphine) is an opioid analgesic and antitussive. Side effects Adverse effects are similar to other opioids and include drowsiness, constipation, vertigo, nausea, vomiting, and respira ...

:R05DA03

Hydrocodone Hydrocodone, also known as dihydrocodeinone, is an opioid used to treat pain and as a cough suppressant. It is taken by mouth. Typically it is dispensed as the combination acetaminophen/hydrocodone or ibuprofen/hydrocodone for pain severe en ...

:R05DA04

Codeine Codeine is an opiate and prodrug of morphine mainly used to treat pain, coughing, and diarrhea. It is also commonly used as a recreational drug. It is found naturally in the sap of the opium poppy, ''Papaver somniferum''. It is typically use ...

:R05DA05 Opium alkaloids with morphine :R05DA06 Normethadone :R05DA07

Noscapine Noscapine (also known as Narcotine, Nectodon, Nospen, Anarcotine and (archaic) Opiane) is a benzylisoquinoline alkaloid, of the phthalideisoquinoline structural subgroup, which has been isolated from numerous species of the family Papaveraceae ( ...

:R05DA08

Pholcodine Pholcodine is an opioid cough suppressant (antitussive). It helps suppress unproductive coughs and also has a mild sedative effect, but has little or no analgesic effects. It is also known as morpholinylethylmorphine and homocodeine. Pholcodine is ...

:R05DA09

Dextromethorphan Dextromethorphan (DXM) is a medication most often used as a cough suppressant in over-the-counter cold and cough medicines. It is sold in syrup, tablet, spray, and lozenge forms. In 2022, the FDA approved a formulation of it combined with bu ...

:R05DA10

Thebacon Thebacon (INN; pronounced ), or dihydrocodeinone enol acetate, is a semisynthetic opioid that is similar to hydrocodone and is most commonly synthesised from thebaine. Thebacon was invented in Germany in 1924, four years after the first synthe ...

:R05DA11

Dimemorfan Dimemorfan ( INN) (or dimemorphan) (brand names Astomin, Dastosirr, Tusben), or dimemorfan phosphate ( JAN), also known as 3,17-dimethylmorphinan, is an antitussive (cough suppressant) of the morphinan family that is widely used in Japan and is a ...

:R05DA12

Acetyldihydrocodeine Acetyldihydrocodeine is an opiate derivative discovered in Germany in 1914 and was used as a cough suppressant and analgesic. It is not commonly used, but has activity similar to other opiates. Acetyldihydrocodeine is a very close relative de ...

:R05DA20 Combinations ''(QR05DA20 Combinations of opium alkaloids and derivatives)'' :QR05DA90

Butorphanol Butorphanol is a morphinan-type synthetic agonist–antagonist opioid analgesic developed by Bristol-Myers. Butorphanol is most closely structurally related to levorphanol. Butorphanol is available as the tartrate salt in injectable, tablet, and ...

R05DB Other cough suppressants

:R05DB01

Benzonatate Benzonatate, sold under the brand name Tessalon among others, is a medication that reduces cough and hiccups. It is taken by mouth. Use is not recommended in those under the age of ten. Effects generally begin within 20 minutes and last up to ei ...

:R05DB02 Benproperine :R05DB03 Clobutinol :R05DB04

Isoaminile Isoaminile is an antitussive (cough suppressant) used under the trade-name Peracon. The normal therapeutic dose is 40–80 mg of the cyclamate salt, with a maximum of five doses in a 24-hour period. In addition to its central antitussive ...

:R05DB05

Pentoxyverine Pentoxyverine ( rINN) or carbetapentane is an antitussive (cough suppressant) commonly used for cough associated with illnesses like common cold. It is sold over-the-counter in the United States as Solotuss, or in combination with other medicati ...

:R05DB07

Oxolamine Oxolamine is a cough suppressant that is available as a generic drug in many jurisdictions. Oxolamine also has anti-inflammatory activity, which causes a reduction in irritation of the nerve receptors of the respiratory tract. It is mainly u ...

:R05DB09 Oxeladin :R05DB10 Clofedanol :R05DB11 Pipazetate :R05DB12 Bibenzonium bromide :R05DB13

Butamirate Butamirate (or brospamin, trade names Acodeen, Codesin, Pertix, Sinecod, Sinecoden, Sinecodix) is a cough suppressant. It has been marketed in Europe and Mexico, but not in the United States. As the citrate salt, it is sold in the form of lozenge ...

:R05DB14 Fedrilate :R05DB15 Zipeprol :R05DB16 Dibunate :R05DB17 Droxypropine :R05DB18 Prenoxdiazine :R05DB19 Dropropizine :R05DB20 Combinations :R05DB21

Cloperastine Cloperastine (INN) or cloperastin, in the forms of cloperastine hydrochloride ( JAN) (brand names Hustazol, Nitossil, Seki) and cloperastine fendizoate (or hybenzoate), is an antitussive and antihistamine that is marketed as a cough suppressant ...

:R05DB22 Meprotixol :R05DB23 Piperidione :R05DB24

Tipepidine Tipepidine (INN) (brand names Asverin, Antupex, Asvelik, Asvex, Bitiodin, Cofdenin A, Hustel, Nodal, Sotal), also known as tipepidine hibenzate ( JAN), is a synthetic, non-opioid antitussive and expectorant of the thiambutene class. It acts as a ...

:R05DB25 Morclofone :R05DB26

Nepinalone Nepinalone is a cough suppressant. Its brand names include Placatus, Tussolvina, and Nepitus. The effect is evident after 20–30 minutes after administration and persists for at least 4 hours. It acts primarily at the level of the CNS, but also ...

:R05DB27 Levodropropizine :R05DB28 Dimethoxanate :R05DB29 Gefapixant

R05F Cough suppressants and expectorants, combinations

R05FA Opium derivatives and expectorants

:R05FA01 Opium derivatives and mucolytics :R05FA02 Opium derivatives and expectorants

R05FB Other cough suppressants and expectorants

:R05FB01 Cough suppressants and mucolytics :R05FB02 Cough suppressants and expectorants

R05X Other cold preparations

:''Empty group''

References

{{Cough and cold preparations R05