In
neuroanatomy
Neuroanatomy is the study of the structure and organization of the nervous system. In contrast to animals with radial symmetry, whose nervous system consists of a distributed network of cells, animals with bilateral symmetry have segregated, defin ...
, the corona radiata is a
white matter
White matter refers to areas of the central nervous system (CNS) that are mainly made up of myelinated axons, also called tracts. Long thought to be passive tissue, white matter affects learning and brain functions, modulating the distribution ...
sheet that continues inferiorly as the
internal capsule
The internal capsule is a white matter structure situated in the inferomedial part of each cerebral hemisphere of the brain. It carries information past the basal ganglia, separating the caudate nucleus and the thalamus from the putamen and the g ...
and superiorly as the
centrum semiovale
In neuroanatomy, the centrum semiovale, semioval center or centrum ovale is the central area of white matter found underneath the cerebral cortex.
The white matter, located in each hemisphere between the cerebral cortex and nuclei, as a whole ha ...
. This sheet of both ascending and descending
axon
An axon (from Greek ἄξων ''áxōn'', axis), or nerve fiber (or nerve fibre: see spelling differences), is a long, slender projection of a nerve cell, or neuron, in vertebrates, that typically conducts electrical impulses known as action po ...
s carries most of the neural traffic from and to the
cerebral cortex
The cerebral cortex, also known as the cerebral mantle, is the outer layer of neural tissue of the cerebrum of the brain in humans and other mammals. The cerebral cortex mostly consists of the six-layered neocortex, with just 10% consisting of ...
. The corona radiata is associated with the
corticopontine tract
Corticopontine fibers are projections from the cerebral cortex to the pontine nuclei.
Depending upon the lobe of origin, they can be classified as frontopontine fibers, parietopontine fibers, temporopontine fibers
In the human nervous syste ...
, the
corticobulbar tract
In neuroanatomy, the corticobulbar (or corticonuclear) tract is a two-neuron white matter motor pathway connecting the motor cortex in the cerebral cortex to the medullary pyramids, which are part of the brainstem's medulla oblongata (also called ...
, and the
corticospinal tract
The corticospinal tract is a white matter motor pathway starting at the cerebral cortex that terminates on lower motor neurons and interneurons in the spinal cord, controlling movements of the limbs and trunk. There are more than one million neur ...
.
Structure
Projection fibers
The projection fibers consist of efferent and afferent fibers uniting the cortex with the lower parts of the brain and with the spinal cord. In human neuroanatomy, bundles of axons (nerve fibers) called tracts, within the brain, can be cate ...
are afferents carrying information to the
cerebral cortex
The cerebral cortex, also known as the cerebral mantle, is the outer layer of neural tissue of the cerebrum of the brain in humans and other mammals. The cerebral cortex mostly consists of the six-layered neocortex, with just 10% consisting of ...
, and efferents carrying information away from it. The most prominent projection fibers are the corona radiata, which radiate out from the cortex and then come together in the
brain stem
The brainstem (or brain stem) is the posterior stalk-like part of the brain that connects the cerebrum with the spinal cord. In the human brain the brainstem is composed of the midbrain, the pons, and the medulla oblongata. The midbrain is conti ...
. The projection fibers that make up the corona radiata also radiate out of the brain stem via the
internal capsule
The internal capsule is a white matter structure situated in the inferomedial part of each cerebral hemisphere of the brain. It carries information past the basal ganglia, separating the caudate nucleus and the thalamus from the putamen and the g ...
. Cerebral
white matter
White matter refers to areas of the central nervous system (CNS) that are mainly made up of myelinated axons, also called tracts. Long thought to be passive tissue, white matter affects learning and brain functions, modulating the distribution ...
is commonly regarded today as an intricately organized system of fasciculi that facilitate the highest expression of cerebral activity.
Function
Motor pathway
Evidence from subcortical small infarcts suggests that
motor fibers
A motor neuron (or motoneuron or efferent neuron) is a neuron whose cell body is located in the motor cortex, brainstem or the spinal cord, and whose axon (fiber) projects to the spinal cord or outside of the spinal cord to directly or indirectly ...
are
somatotopically
Somatotopy is the point-for-point correspondence of an area of the body to a specific point on the central nervous system. Typically, the area of the body corresponds to a point on the primary somatosensory cortex (postcentral gyrus). This cortex i ...
arranged in the human corona radiata. Following subtotal brain damage, localization of the corticofugal projection in the corona radiata and
internal capsule
The internal capsule is a white matter structure situated in the inferomedial part of each cerebral hemisphere of the brain. It carries information past the basal ganglia, separating the caudate nucleus and the thalamus from the putamen and the g ...
can assist in evaluating a patient's residual motor capacity and predicting their potential for functional restitution. Data suggests that the corona radiata and superior capsular lesions may correlate with more favorable levels of functional recovery. Lesions seated inferiorly are likely to correlate with poorer levels of recovery regarding upper limb movement. Findings also suggest that motor deficit severity is likely to increase as a lesion occupies progressively more posterior regions of the internal capsule.
Clinical significance
Th
corona radiatamay be affected by diseases affecting the cerebral
white matter
White matter refers to areas of the central nervous system (CNS) that are mainly made up of myelinated axons, also called tracts. Long thought to be passive tissue, white matter affects learning and brain functions, modulating the distribution ...
, including ischemic
leukoencephalopathy Leukoencephalopathy (leukodystrophy-like diseases) is a term that describes all of the brain white matter diseases, whether their molecular cause is known or unknown. It can refer specifically to any of these diseases:
* Progressive multifocal leuk ...
,
multiple sclerosis
Multiple (cerebral) sclerosis (MS), also known as encephalomyelitis disseminata or disseminated sclerosis, is the most common demyelinating disease, in which the insulating covers of nerve cells in the brain and spinal cord are damaged. This d ...
, and progressive
leukoencephalopathy Leukoencephalopathy (leukodystrophy-like diseases) is a term that describes all of the brain white matter diseases, whether their molecular cause is known or unknown. It can refer specifically to any of these diseases:
* Progressive multifocal leuk ...
. These may have major effects on intellectual, social, and emotional functioning.
In
normal pressure hydrocephalus
Normal-pressure hydrocephalus (NPH), also called malresorptive hydrocephalus, is a form of communicating hydrocephalus in which excess cerebrospinal fluid (CSF) occurs in the ventricles, and with normal or slightly elevated cerebrospinal fluid p ...
, expansion of the lateral ventricles causes distortion of the fibers of the corona radiata. This contributes to the urinary incontinence seen with NPH.
Additional images
File:Gray682.png, Superficial dissection of brain-stem. Lateral view.
External links
*
Somatotopic Organization of Motor Fibers in the Corona Radiata in Monoparetic Patients With Small Subcortical InfarctLocalization of arm representation in the corona radiata and internal capsule in the non‐human primateSomatotopically located motor fibers in corona radiata: Evidence from subcortical small infarctsFiber Tract–based Atlas of Human White Matter AnatomyColor Atlas of Neuroscience: Neuroanatomy and Neurophysiology:Meninges and Tractsat
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Cerebral white matter