The
Computational Biology
Computational biology refers to the use of data analysis, mathematical modeling and computational simulations to understand biological systems and relationships. An intersection of computer science, biology, and big data, the field also has fo ...
Department (CBD) is a division within the
School of Computer Science at
Carnegie Mellon University
Carnegie Mellon University (CMU) is a private research university in Pittsburgh, Pennsylvania. One of its predecessors was established in 1900 by Andrew Carnegie as the Carnegie Technical Schools; it became the Carnegie Institute of Technology ...
in
Pittsburgh
Pittsburgh ( ) is a city in the Commonwealth (U.S. state), Commonwealth of Pennsylvania, United States, and the county seat of Allegheny County, Pennsylvania, Allegheny County. It is the most populous city in both Allegheny County and Wester ...
,
Pennsylvania
Pennsylvania (; ( Pennsylvania Dutch: )), officially the Commonwealth of Pennsylvania, is a state spanning the Mid-Atlantic, Northeastern, Appalachian, and Great Lakes regions of the United States. It borders Delaware to its southeast, ...
,
United States
The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territorie ...
. It is located in the Gates-Hillman Center. Established in 2007 by
Robert F. Murphy as the Lane Center for Computational Biology with funding from
Raymond J. Lane
Raymond J. Lane (born December 26, 1946) is an American business executive and strategist specializing in technology and finance. Lane is best known for assisting corporations with technology strategy, organizational development, team building, ...
and Stephanie Lane, CBD became a department within the School of Computer Science in 2016.
CBD faculty and students conduct research in
genomics
Genomics is an interdisciplinary field of biology focusing on the structure, function, evolution, mapping, and editing of genomes. A genome is an organism's complete set of DNA, including all of its genes as well as its hierarchical, three-dim ...
,
systems biology
Systems biology is the computational modeling, computational and mathematical analysis and modeling of complex biological systems. It is a biology-based interdisciplinary field of study that focuses on complex interactions within biological syst ...
, and
biological imaging Biological imaging may refer to any imaging technique used in biology.
Typical examples include:
* Bioluminescence imaging, a technique for studying laboratory animals using luminescent protein
* Calcium imaging, determining the calcium status of a ...
. Its faculty have served as president of the
National Science Foundation
The National Science Foundation (NSF) is an independent agency of the United States government that supports fundamental research and education in all the non-medical fields of science and engineering. Its medical counterpart is the National I ...
, president of the International Society of Advanced Cytometry, and as a member of the
National Institutes of Health
The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late ...
Council of Councils; they have won awards such as the
Overton Prize The ISCB Overton Prize is a Awards in Bioinformatics and Computational Biology, computational biology prize awarded annually for outstanding accomplishment by a scientist in the early to mid stage of his or her career. Laureates have made significan ...
, a
Guggenheim Fellowship
Guggenheim Fellowships are grants that have been awarded annually since by the John Simon Guggenheim Memorial Foundation to those "who have demonstrated exceptional capacity for productive scholarship or exceptional creative ability in the ar ...
, th
Okawa Award a
United States Air Force
The United States Air Force (USAF) is the air service branch of the United States Armed Forces, and is one of the eight uniformed services of the United States. Originally created on 1 August 1907, as a part of the United States Army Signal ...
Young Investigator Award, and a
Presidential Young Investigator Award
The Presidential Young Investigator Award (PYI) was awarded by the National Science Foundation of the United States Federal Government. The program operated from 1984 to 1991, and was replaced by the NSF Young Investigator (NYI) Awards and Presiden ...
.
As part of the HHMI-NIBIB Interfaces Initiative, CBD received funding from
Howard Hughes Medical Institute
The Howard Hughes Medical Institute (HHMI) is an American non-profit medical research organization based in Chevy Chase, Maryland. It was founded in 1953 by Howard Hughes, an American business magnate, investor, record-setting pilot, engineer, fil ...
and the
National Institute of Biomedical Imaging and Bioengineering
The National Institute of Biomedical Imaging and Bioengineering (NIBIB), founded at the National Institutes of Health (NIH) in 2000, is located in Bethesda, Maryland. It is one of 27 institutes and centers that are part of NIH, an agency of the U ...
(NIBIB) to develop an interdisciplinary Ph.D. program in
computational biology
Computational biology refers to the use of data analysis, mathematical modeling and computational simulations to understand biological systems and relationships. An intersection of computer science, biology, and big data, the field also has fo ...
with the
University of Pittsburgh
The University of Pittsburgh (Pitt) is a public state-related research university in Pittsburgh, Pennsylvania. The university is composed of 17 undergraduate and graduate schools and colleges at its urban Pittsburgh campus, home to the universit ...
, which was founded as the
Joint CMU-Pitt Ph.D. Program in Computational Biology
The Joint CMU-Pitt Ph.D Program in Computational Biology (CPCB) is an interdisciplinary graduate training program in computational biology. It is a joint program between Carnegie Mellon University and the University of Pittsburgh in Pittsburgh
...
in 2005. This program is currently receiving training support through a National Institutes of Health T32 Training Grant. CBD is the home of the B.S. in Computational Biology,
one of the four B.S. degree programs within
Carnegie Mellon School of Computer Science
The School of Computer Science (SCS) at Carnegie Mellon University in Pittsburgh, Pennsylvania, US is a school for computer science established in 1988. It has been consistently ranked among the top computer science programs over the decades. A ...
. The Computational Biology undergraduate program is ranked as one of the top 3 programs by US News.
CBD is the home of an NIH Center for the
HuBMAP
The Human Biomolecular Atlas Program (HuBMAP) is a program funded by the US National Institutes of Health to characterize the human body at single cell resolution, integrated to other efforts such as the Human Cell Atlas. Among the products of the ...
Integration, Visualization & Engaging (HIVE) Initiative led by
Ziv Bar-Joseph
Ziv Bar-Joseph is an Israeli computational biologist and Professor in the Computational Biology Department and the Machine Learning Department at the Carnegie Mellon School of Computer Science.
Education
Bar-Joseph studied computer science at Bac ...
and an NIH Center for Multiscale Analysis of 4D Nucleome Structure and Function by Comprehensive Multimodal Data Integration led by
Jian Ma.
Notable faculty
*
Robert F. Murphy (founding chair)
* Russell Schwartz (chair)
*
Ziv Bar-Joseph
Ziv Bar-Joseph is an Israeli computational biologist and Professor in the Computational Biology Department and the Machine Learning Department at the Carnegie Mellon School of Computer Science.
Education
Bar-Joseph studied computer science at Bac ...
*
Jaime Carbonell
Jaime Guillermo Carbonell (July 29, 1953 – February 28, 2020) was a computer scientist who made seminal contributions to the development of natural language processing tools and technologies. His extensive research in machine translation result ...
*
Jian Ma
*
Kathryn Roeder
Kathryn M. Roeder is an American statistician known for her development of statistical methods to uncover the genetic basis of complex disease and her contributions to mixture models, semiparametric inference, and multiple testing. Roeder holds po ...
*
Roni Rosenfeld
Roni Rosenfeld is an Israeli-American computer scientist and computational epidemiologist, currently serving as the head of thMachine Learning Departmentat Carnegie Mellon University. He is an international expert in machine learning, infectious ...
*
Eric Xing
Eric Poe Xing is an American computer scientist, academic administrator, and entrepreneur. Prior to his appointment as President of MBZUAI, Xing was a professor in the School of Computer Science at Carnegie Mellon University and researcher in mac ...
Notable meetings hosted
*
RECOMB 2014
* Great Lakes Bioinformatics Conference 2013 (joint with University of Pittsburgh)
* Automated Personal Genome Analysis (APGA) 2013
* Bioimage Informatics 2010
Degree programs
* Joint CMU-Pitt Ph.D. Program in Computational Biology (with
University of Pittsburgh
The University of Pittsburgh (Pitt) is a public state-related research university in Pittsburgh, Pennsylvania. The university is composed of 17 undergraduate and graduate schools and colleges at its urban Pittsburgh campus, home to the universit ...
)
* M.S. in Computational Biology (joint with the Department of Biological Sciences)
* M.S. in Biotechnology Innovation and Computation (joint with
Language Technologies Institute
The Language Technologies Institute (LTI) is a research institute at Carnegie Mellon University in Pittsburgh, Pennsylvania, United States, and focuses on the area of language technologies. The institute is home to 33 faculty with the primary scho ...
)
* B.S. in Computational Biology
* Minor in Computational Biology
References
{{Carnegie Mellon, state=uncollapsed
Schools and departments of Carnegie Mellon
University departments in the United States
Bioinformatics organizations
Organizations established in 2007
2007 establishments in Pennsylvania