Comins' Reagent
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The Comins' reagent is a
triflyl In organic chemistry, the triflyl group (systematic name: trifluoromethanesulfonyl group) is a functional group with the formula and structure . The triflyl group is often represented by –Tf. The related triflate group (trifluoromethanesulfo ...
-donating reagent that is used to synthesize vinyl
triflates In organic chemistry, triflate (systematic name: trifluoromethanesulfonate), is a functional group with the formula and structure . The triflate group is often represented by , as opposed to −Tf, which is the triflyl group, . For example, ' ...
from the corresponding ketone enolates or dienolates. It was first reported in 1992 by Daniel Comins. The vinyl triflates prepared are useful as substrates in the
Suzuki reaction The Suzuki reaction is an organic reaction, classified as a cross-coupling reaction, where the coupling partners are a boronic acid and an organohalide and the catalyst is a palladium(0) complex. It was first published in 1979 by Akira Suzuki, ...
.


See also

*
Bis(trifluoromethanesulfonyl)aniline Bis(trifluoromethanesulfonyl)aniline is the organic compound with the formula C6H5N(SO2CF3)2.{{cite journal, title=N-Phenyltrifluoromethanesulfonimide , last1=Zeller, first1=Wayne E., last2=Schwörer, first2=Ralf, journal=E-EROS Encyclopedia of Re ...


References

Reagents for organic chemistry Chloropyridines Sulfonamides Trifluoromethyl compounds Substances discovered in the 1990s {{organic-compound-stub