Coca Alkaloid
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Coca alkaloids are the
alkaloid Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds with neutral and even weakly acidic properties. Some synthetic compounds of similar ...
s found in the coca plant, ''
Erythroxylum coca ''Erythroxylum coca'' is one of two species of cultivated coca. Description The coca plant resembles a blackthorn bush, and grows to a height of . The branches are straight, and the leaves, which have a green tint, are thin, opaque, oval, and tap ...
''.Variation of Alkaloid Content in Erythroxylum coca Leaves from Leaf Bud to Leaf Drop. Emanuel L. Johnson and Stephen D. Emche, Ann. Bot., 1994, volume 73, issue 6, pages 645-650, They are predominantly of either the pyrrolidine or the
tropane Tropane is a nitrogenous bicyclic organic compound. It is mainly known for the other alkaloids derived from it, which include atropine and cocaine, among others. Tropane alkaloids occur in plants of the families Erythroxylaceae (including coca) ...
types. __NOTOC__


Tropane-type alkaloids

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Benzoylecgonine Benzoylecgonine is the main metabolite of cocaine, formed by the liver and excreted in the urine. It is the compound tested for in most cocaine urine drug screens. Pharmacokinetics Chemically, benzoylecgonine is the benzoate ester of ecgonine. I ...
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Cocaine Cocaine (from , from , ultimately from Quechua: ''kúka'') is a central nervous system (CNS) stimulant mainly used recreationally for its euphoric effects. It is primarily obtained from the leaves of two Coca species native to South Ameri ...
* Ecgonidine *
Ecgonine Ecgonine (tropane derivative) is a tropane alkaloid found naturally in coca leaves. It has a close structural relation to cocaine: it is both a metabolite and a precursor, and as such, it is a controlled substance in many jurisdictions, as are s ...
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Hydroxytropacocaine Hydroxytropacocaine is a tropane alkaloid found in ''Erythroxylum coca''. See also * Coca alkaloid Coca alkaloids are the alkaloids found in the coca plant, ''Erythroxylum coca''.Variation of Alkaloid Content in Erythroxylum coca Leaves from L ...
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Methylecgonine cinnamate Methylecgonine cinnamate is a natural tropane alkaloid found within the coca plant. Its more common name, cinnamoylcocaine, reflects its close structural similarity to cocaine. It is pharmacologically inactive,Merck Chemical Index, 1985 but some ...
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Tropacocaine Tropacocaine (tropacaine, benzoylpseudotropine, pseudotropine benzoate, descarbomethoxycocaine) is a cocaine-related alkaloid Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom. Thi ...
* Truxilline


Pyrrolidine-type alkaloids

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Cuscohygrine Cuscohygrine is a pyrrolidine alkaloid found in coca. It can also be extracted from plants of the family Solanaceae, including ''Atropa belladonna'' (deadly nightshade), ''Datura innoxia'' and ''Datura stramonium'' (jimson weed). Cuscohygrine usua ...
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Dihydrocuscohygrine Dihydrocuscohygrine is an alkaloid that has been isolated from coca Coca is any of the four cultivated plants in the family Erythroxylaceae, native to western South America. Coca is known worldwide for its psychoactive alkaloid, cocaine. The ...
* Hygrine *
Nicotine Nicotine is a natural product, naturally produced alkaloid in the nightshade family of plants (most predominantly in tobacco and ''Duboisia hopwoodii'') and is widely used recreational drug use, recreationally as a stimulant and anxiolytic. As ...


See also

* Cocaine metabolites (Human) *
Coca wine Coca wine is an alcoholic beverage combining wine with cocaine. One popular brand was ''Vin Mariani'', developed in 1863 by French-Corsican chemist and entrepreneur Angelo Mariani. At the end of the 19th century, the fear of drug abuse made coc ...
, an alcoholic beverage combining wine with extracted coca alkaloids *
Methylecgonidine Methylecgonidine (anhydromethylecgonine; anhydroecgonine methyl ester; AEME) is a chemical intermediate derived from ecgonine or cocaine. Methylecgonidine is a pyrolysis product formed when crack cocaine is smoked, making this substance a useful ...
*
Troparil Troparil (also known as (–)-2β-Carbomethoxy-3β-phenyltropane, WIN 35,065-2, or β-CPT) is a stimulant drug used in scientific research. Troparil is a phenyltropane-based dopamine reuptake inhibitor (DRI) that is derived from methylecgonidine ...


References

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