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''Cnidium monnieri'' (L.) Cusson ex Juss., Monnier's snowparsley, is a flowering plant species in the genus ''
Cnidium ''Cnidium'' is a genus of flowering plants in the family Apiaceae, native to Eurasia and North America. Species , Plants of the World Online accepted the following species: *''Cnidium bhutanicum'' M.F.Watson *''Cnidium cnidiifolium'' (Turcz.) Sc ...
''. Also known as Shechuangzi, Osthole, Jashoshi, Cnidii Fructus (Fruits of Cnidium). It may be confused with ''
Bacopa monnieri ''Bacopa monnieri'' is a perennial, creeping herb native to the wetlands of southern and Eastern India, Australia, Europe, Africa, Asia, and North and South America. It is known by the common names water hyssop, waterhyssop, brahmi, thyme-leafed ...
'', ''
Ligusticum officinale ''Ligusticum'' (lovage, licorice root) is a genus of about 60 species of flowering plants in the family Apiaceae, native to cool temperate regions of the Northern Hemisphere. Its name is believed to derive from the Italian region of Liguria.Huxle ...
'' (syn. ''Cnidium officinale''), both similar but different plants. The
coumarins Coumarin () or 2''H''-chromen-2-one is an aromatic organic chemical compound with formula . Its molecule can be described as a benzene molecule with two adjacent hydrogen atoms replaced by a lactone-like chain , forming a second six-membered h ...
osthol Osthol, or osthole, is a chemical compound which is a derivative of coumarin. It is found in a variety of plants including ''Cnidium monnieri'', ''Angelica archangelica ''Angelica archangelica'', commonly known as garden angelica, wild celery, a ...
,
imperatorin Imperatorin is a furocoumarin and a phytochemical that has been isolated from ''Urena lobata'' L. (Malvaceae), ''Angelica archangelica'', '' Angelica dahurica'', '' Glehnia littoralis'', '' Saposhnikovia divaricata'', ''Cnidium monnieri'', '' Inca ...
and
xanthotoxol Xanthotoxol is a furanocoumarin. It is one of the major active ingredients in ''Cnidium monnieri''.Xanthotoxol exerts neuroprotective effects via suppression of the inflammatory response in a rat model of focal cerebral ischemia. He W, Chen W, Zhou ...
can be found in ''C. monnieri''.


Naming

''Cnidium monnieri'' was already described and the name validly published by Carl Linnaeus. It was Pierre Cusson, however, who reclassified it into today's valid botanical systematics in 1787.


Taxonomy

''Cnidium monnieri'' is a species in the genus ''Cnidium'' which contains approximately 11 to 35 species and belongs to th
family
of th
Apiaceae
(carrot family).


Characteristics

Plants annual, 10–60(–80) cm. Taproot 2–3 mm thick. Stem solitary, striate, scabrous. Lower petioles 3–8 cm; blade ovate-lanceolate, 3–8 × 2–5 cm, 2–3-pinnate; ultimate segments linear to linear-lanceolate, 3–10 × 1–1.5 mm, veins and margins scabrous. Umbels 2–3(–5) cm across; bracts 6–10, linear to linear-lanceolate, 2–3 mm, persistent, margins narrowly white membranous, very finely ciliate; rays 8–20(–30), 5–20 mm, unequal; bracteoles 5–9, linear, nearly equal pedicels, margins ciliate; umbellules 15–20-flowered; pedicels 3–5 mm. Calyx teeth obsolete or minute. Stylopodium conic; styles 3–4 times longer than stylopodium. Fruit ovoid, 1.5–3 × 1–2 mm; lateral ribs slightly broader than the dorsal. Seed face plane. Fl. Apr–Jul, fr. Jul–Oct.


Growth

The plants reach heights of 10 to 80 centimetres.


Leaves

''Cnidium monnieri'' has
bipinnate The following is a list of terms which are used to describe leaf morphology in the description and taxonomy of plants. Leaves may be simple (a single leaf blade or lamina) or compound (with several leaflets). The edge of the leaf may be regular o ...
leaves that are alternate. The linear leaflets are ciliate and petiolate.


Flowers and fruits

''Cnidium monnieri'' produces compound umbels of white five-stellate flowers from April to July. The plants produce
achenes An achene (; ), also sometimes called akene and occasionally achenium or achenocarp, is a type of simple dry fruit produced by many species of flowering plants. Achenes are monocarpellate (formed from one carpel) and indehiscent (they do not ope ...
.


Distribution

''Cnidium monnieri'' is native to India, China, Korea, Laos, Mongolia, Vietnam, the European Russia (Belarus, Ukraine, Moldova, Crimea) and Europe. Grows in riparian grasslands and is adventive in North America (Oregon).


Cultivation

Pests and Diseases Literature: * Walter Erhardt, Erich Götz, Nils Bödeker, Siegmund Seybold: ''Der große Zander.'' Eugen Ulmer KG, Stuttgart 2008, . (Ger.) * Christoper Brickell (Editor-in-chief): ''RHS A-Z Encyclopedia of Garden Plants.'' Third edition. Dorling Kindersley, London 2003, .


Medicinal use

''Cnidium monnieri'' (L.) Cuss. is one of the most widely used traditional herbal medicines and its fruits have been used to treat a variety of diseases in China, Vietnam, and Japan. As of this writing, 350 compounds have been isolated and identified from ''C. monnieri'', including the main active constituent,
coumarins Coumarin () or 2''H''-chromen-2-one is an aromatic organic chemical compound with formula . Its molecule can be described as a benzene molecule with two adjacent hydrogen atoms replaced by a lactone-like chain , forming a second six-membered h ...
. In vitro and in vivo studies suggest that osthole and other coumarin compounds possess wide range of pharmacological properties effective in the treatment of disorders of the female genitalia, male impotence, frigidity, skin-related diseases, and that, in this context, they exhibit strong antipruritic, anti-allergic, antidermatophytic, antibacterial, antifungal, anti-osteoporotic effects. Although coumarins have been identified as the main active constituents responsible for the observed pharmacological effects, the molecular mechanisms of their actions are still unknown. A pro-erectile herb from traditional Chinese medicine, ''Cnidium monnieri'' and its main bioactive known as osthole appear to have mechanisms similar to Viagra in penile tissue and the
hippocampus The hippocampus (via Latin from Greek , 'seahorse') is a major component of the brain of humans and other vertebrates. Humans and other mammals have two hippocampi, one in each side of the brain. The hippocampus is part of the limbic system, a ...
; the influence of ''Cnidium monnieri'' on testosterone and cognition remains unexplored.


References


External links


Cnidium monnieri
at the ''United States Department of Agriculture''
Cnidium monnieri
in the ''Flora of China'' {{Taxonbar, from=Q12842240 Apioideae Plants described in 1755