Clyster (beetle)
   HOME

TheInfoList



OR:

An enema, also known as a clyster, is an injection of fluid into the lower bowel by way of the
rectum The rectum is the final straight portion of the large intestine in humans and some other mammals, and the Gastrointestinal tract, gut in others. The adult human rectum is about long, and begins at the rectosigmoid junction (the end of the s ...
.Cullingworth, ''A Manual of Nursing, Medical and Surgical'':155 The word enema can also refer to the liquid injected, as well as to a device for administering such an injection. In standard medicine, the most frequent uses of enemas are to relieve constipation and for bowel cleansing before a medical examination or procedure; also, they are employed as a lower gastrointestinal series (also called a barium enema), to treat traveler's diarrhea, as a vehicle for the administration of food, water or medicine, as a stimulant to the general system, as a local application and, more rarely, as a means of reducing temperature, as treatment for encopresis, and as a form of
rehydration therapy The management of dehydration typically involves the use of Oral rehydration therapy, oral rehydration solution (ORS). Standard home solutions such as salted rice water, salted yogurt drinks, vegetable and chicken soups with salt can be given. Hom ...
(proctoclysis) in patients for whom
intravenous therapy Intravenous therapy (abbreviated as IV therapy) is a medical technique that administers fluids, medications and nutrients directly into a person's vein. The intravenous route of administration is commonly used for rehydration or to provide nutri ...
is not applicable. In other contexts, enemas are used by some alternative health therapies, used for enjoyment, chiefly as part of sexual activities, but also in BDSM, as well as simply for pleasure, used to intoxicate with alcohol, used to administer drugs for both recreational and religious reasons, and used for punishment.


Medical usage

The principal medical usages of enemas are:


Bowel cleansing


Acute treatments

As bowel stimulants, enemas are employed for the same purposes as orally administered laxatives: To relieve constipation; To treat fecal impaction; To empty the colon prior to a medical procedure such as a
colonoscopy Colonoscopy () or coloscopy () is the endoscopic examination of the large bowel and the distal part of the small bowel with a CCD camera or a fiber optic camera on a flexible tube passed through the anus. It can provide a visual diagnosis (''e. ...
. When oral laxatives are not indicated or are not sufficiently effective, enemas may be a sensible and necessary measure. A large volume of enema can be given to cleanse as much of the colon as possible of feces. However, a low enema is generally useful only for stool in the rectum, not in the intestinal tract. Such enemas' mechanism consists of the volume of the liquid causing rapid expansion of the intestinal tract in conjunction with, in the case of certain solutions, irritation of the intestinal
mucosa A mucous membrane or mucosa is a membrane that lines various cavities in the body of an organism and covers the surface of internal organs. It consists of one or more layers of epithelial cells overlying a layer of loose connective tissue. It is ...
which stimulates peristalsis and lubricates the stool to encourage a bowel movement. An enema's efficacy depends on several factors including the volume injected and the temperature and the contents of the infusion. In order for the enema to be effective the patient should retain the solution for five to ten minutes, as tolerated. or, as some nursing textbooks recommend, for five to fifteen minutes or as long as possible.


= Large volume enemas

= For emptying the entire colon as much as feasible deeper and higher enemas are utilized to reach large sections of the colon. The colon dilates and expands when a large volume of liquid is injected into it, and the colon reacts to that sudden expansion with general contractions, peristalsis, propelling its contents toward the rectum. Soapsuds enema is a frequently used synonym for a large volume enema (although soap is not necessary for effectivity). For relieving occasional constipation, a large volume enema may be used in a home setting, although for recurring or severe cases of constipation medical care may be required.


Water-based solutions

Plain water can be used, simply functioning mechanically to expand the colon, thus prompting evacuation. Normal saline is least irritating to the colon. Like plain water, it simply functions mechanically to expand the colon, but having a neutral concentration gradient, it neither draws
electrolyte An electrolyte is a medium containing ions that is electrically conducting through the movement of those ions, but not conducting electrons. This includes most soluble salts, acids, and bases dissolved in a polar solvent, such as water. Upon dis ...
s from the body, as happens with plain water, nor draws water into the colon, as occurs with phosphates. Thus, a salt water solution can be used when a longer period of retention is desired, such as to soften an impaction.
Castile soap Castile soap is an olive oil based hard soap made in a style similar to that originating in the Castile region of Spain. History The origins of Castile soap go back to the Levant, where Aleppo soap-makers have made hard soaps based on olive ...
is commonly added because its irritation of the colon's lining increases the urgency to defecate. However, liquid handsoaps and detergents should not be used. Glycerol is a specific bowel mucosa irritant serving to induce peristalsis via a hyperosmotic effect. It is used in a dilute solution, e.g., 5%.


Other solutions

Equal parts of milk and molasses heated together to slightly above normal body temperature have been used. Neither the milk sugars and proteins nor the molasses are absorbed in the lower intestine, thus keeping the water from the enema in the intestine. Studies have shown that milk and molasses enemas have a low complication rate when used in the
emergency department An emergency department (ED), also known as an accident and emergency department (A&E), emergency room (ER), emergency ward (EW) or casualty department, is a medical treatment facility specializing in emergency medicine, the acute care of pati ...
and are safe and effective with minimal side effects. Mineral oil functions as a lubricant and stool softener, but may have side effects including rectal skin irritation and leakage of oil.


= Micro-enemas

=


ATC codes for drugs for constipation — enemas

:A06AG01 Sodium phosphate :A06AG02 Bisacodyl :A06AG03 Dantron, including combinations :A06AG04 Glycerol :A06AG06 Oil :A06AG07
Sorbitol Sorbitol (), less commonly known as glucitol (), is a sugar alcohol with a sweet taste which the human body metabolizes slowly. It can be obtained by reduction of glucose, which changes the converted aldehyde group (−CHO) to a primary alcohol g ...
:A06AG10
Docusate sodium Docusate is the common chemical and pharmaceutical name of the anion bis(2-ethylhexyl) sulfosuccinate, also commonly called dioctyl sulfosuccinate (DOSS). It is on the World Health Organization's List of Essential Medicines. Salts of this anion ...
, including combinations :A06AG11 Sodium lauryl sulfoacetate, including combinations :A06AG20 Combinations


Single substance solutions

''In alphabetical order'' Arachis oil (peanut oil) enema is useful for softening stools which are impacted higher than the rectum. Bisacodyl stimulates enteric nerves to cause colonic contractions. Dantron is a stimulant drug and stool softener used alone or in combinations in enemas. Considered to be a carcinogen its use is limited, e.g., restricted in the UK to patients who already have a diagnosis of terminal cancer and not used at all in the
USA The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country Continental United States, primarily located in North America. It consists of 50 U.S. state, states, a Washington, D.C., ...
. Docusate Glycerol has a hyperosmotic effect and can be used as a small-volume (2–10 ml) enema (or suppository). Mineral oil is used as a lubricant because most of the ingested material is excreted in the stool rather than being absorbed by the body. Sodium phosphate. Also known by the brand name Fleet. Available at drugstores; usually self-administered. Buffered sodium phosphate solution draws additional water from the bloodstream into the colon to increase the effectiveness of the enema. But it can be rather irritating to the colon, causing intense cramping or "griping." Fleet enemas usually causes a bowel movement in 1 to 5 minutes. Known adverse effects.
Sorbitol Sorbitol (), less commonly known as glucitol (), is a sugar alcohol with a sweet taste which the human body metabolizes slowly. It can be obtained by reduction of glucose, which changes the converted aldehyde group (−CHO) to a primary alcohol g ...
pulls water into the large intestines causing distention, thereby stimulating the normal forward movement of the bowels. Sorbitol is found in some dried fruits and may contribute to the laxative effects of prunes. and is available for taking orally as a laxative. As an enema for constipation, the recommended adult dose is 120 mL of 25-30% solution, administered once. Note that Sorbitol is an ingredient of the MICROLAX Enema.


Compounded from multiple ingredients

''In alphabetical order of the original brand names'' Klyx contains
docusate sodium Docusate is the common chemical and pharmaceutical name of the anion bis(2-ethylhexyl) sulfosuccinate, also commonly called dioctyl sulfosuccinate (DOSS). It is on the World Health Organization's List of Essential Medicines. Salts of this anion ...
1 mg/mL and sorbitol solution (70%) (crystallising) 357 mg/mL and is used for faecal impaction or constipation or for colon evacuation prior medical procedures, developed by Ferring B.V. Micralax (not to be confused with MICROLAX®) MICROLAX® (not to be confused with Micralax) combines the action of sodium citrate, a peptidising agent which can displace bound water present in the faeces, with sodium alkyl sulphoacetate, a wetting agent, and with glycerol, an anal mucosa irritant and hyperosmotic. However, also sold under the name "Micralax", is a preparation containing
sorbitol Sorbitol (), less commonly known as glucitol (), is a sugar alcohol with a sweet taste which the human body metabolizes slowly. It can be obtained by reduction of glucose, which changes the converted aldehyde group (−CHO) to a primary alcohol g ...
rather than glycerol; which was initially tested in preparation for sigmoidoscopy. Micolette Micro-enema® contains 45 mg sodium lauryl sulphoacetate, 450 mg per 5 ml sodium citrate BP, and 625 mg glycerol BP and is a small volume stimulant enema suitable where large-volume enemas are contra-indicated.


Chronic treatments


= Transanal irrigation

= ''TAI'', also termed ''retrograde irrigation'', is designed to assist evacuation using a water enema as a treatment for persons with bowel dysfunction, including fecal incontinence or constipation, especially obstructed defecation. By regularly emptying the bowel using transanal irrigation,
Consensus review of best practice of transanal irrigation in adults A V Emmanuel et al. Spinal Cord 2013.
controlled bowel function is often re-established to a high degree, thus enabling development of a consistent bowel routine. Its effectiveness varies considerably, some individuals experiencing complete control of incontinence but others reporting little or no benefit. An international consensus on when and how to use transanal irrigation for people with bowel problems was published in 2013, offering practitioners a clear, comprehensive and simple guide to practice for the emerging therapeutic area of transanal irrigation. The term ''retrograde irrigation'' distinguishes this procedure from the Malone antegrade continence enema, where irrigation fluid is introduced into the colon proximal to the anus via a surgically created irrigation port.


= Bowel management

= Patients who have a bowel disability, a medical condition which impairs control of
defecation Defecation (or defaecation) follows digestion, and is a necessary process by which organisms eliminate a solid, semisolid, or liquid waste material known as feces from the digestive tract via the anus. The act has a variety of names ranging f ...
, e.g., fecal incontinence or constipation, can use bowel management techniques to choose a predictable time and place to evacuate. Without bowel management, such persons might either suffer from the feeling of not getting relief, or they might soil themselves. While simple techniques might include a controlled diet and establishing a toilet routine, a daily enema can be taken to empty the colon, thus preventing unwanted and uncontrolled bowel movements that day.Peña A, Guardino K, Tovilla JM, Levitt MA, Rodriguez G, Torres R Bowel management for fecal incontinence in patients with anorectal malformations Pediatr. Surg. 33:1 133–7 1998


Contrast (X-ray)

In a lower gastrointestinal series an enema that may contain
barium sulfate Barium sulfate (or sulphate) is the inorganic compound with the chemical formula Ba SO4. It is a white crystalline solid that is odorless and insoluble in water. It occurs as the mineral barite, which is the main commercial source of barium an ...
powder or a water-soluble contrast agent is used in the radiological imaging of the bowel. Called a ''barium enema'', such enemas are sometimes the only practical way to ''view'' the colon in a relatively safe manner. Failure to expel all of the barium may cause constipation or possible impaction and a patient who has no bowel movement for more than two days or is unable to pass gas rectally should promptly inform a physician and may require an enema or laxative.


Medication administration

The administration of substances into the bloodstream. This may be done in situations where it is undesirable or impossible to deliver a medication by mouth, such as antiemetics given to reduce nausea (though not many antiemetics are delivered by enema). Additionally, several anti-angiogenic agents, which work better without digestion, can be safely administered via a gentle enema. The topical administration of medications into the rectum, such as
corticosteroids Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones. Two main classes of corticosteroids, glucocorticoids and mineralocorticoids, are involve ...
and mesalazine used in the treatment of
inflammatory bowel disease Inflammatory bowel disease (IBD) is a group of inflammation, inflammatory conditions of the colon (anatomy), colon and small intestine, Crohn's disease and ulcerative colitis being the principal types. Crohn's disease affects the small intestine a ...
. Administration by enema avoids having the medication pass through the entire
gastrointestinal tract The gastrointestinal tract (GI tract, digestive tract, alimentary canal) is the tract or passageway of the digestive system that leads from the mouth to the anus. The GI tract contains all the major organ (biology), organs of the digestive syste ...
, therefore simplifying the delivery of the medication to the affected area and limiting the amount that is absorbed into the bloodstream. Rectal corticosteroid enemas are sometimes used to treat mild or moderate ulcerative colitis. They also may be used along with systemic (oral or injection) corticosteroids or other medicines to treat severe disease or mild to moderate disease that has spread too far to be treated effectively by medicine inserted into the rectum alone.


Inhibiting pathological defecation

*
Traveller's diarrhea Travelers' diarrhea (TD) is a stomach and intestinal infection. TD is defined as the passage of unformed stool (one or more by some definitions, three or more by others) while traveling. It may be accompanied by abdominal cramps, nausea, fever, ...
's symptoms treated with an enema of
sodium butyrate Sodium butyrate is a compound with formula Na(C3H7COO). It is the sodium salt of butyric acid. It has various effects on cultured mammalian cells including inhibition of proliferation, induction of differentiation and induction or repression of ...
,
organic acid An organic acid is an organic compound with acidic properties. The most common organic acids are the carboxylic acids, whose acidity is associated with their carboxyl group –COOH. Sulfonic acids, containing the group –SO2OH, are rel ...
s, and A-300 silicon dioxide can be successfully decreased with lack of observed side effects. *
Shigellosis Shigellosis is an infection of the intestines caused by ''Shigella'' bacteria. Symptoms generally start one to two days after exposure and include diarrhea, fever, abdominal pain, and feeling the need to pass stools even when the bowels are emp ...
treatment benefits from adjunct therapy with butyrate enemas, promoting healing of the rectal mucosa and inflammation, but not helping in clinical recovery from shigellosis. Use of an 80 ml of a sodium butyrate isotonic enema administered every 12 hours has been studied and found effective.


Other

* There have been a few cases in remote or rural settings, where rectal fluids have been used to rehydrate a person. Benefits include not needing to use sterile fluids. * Introducing healthy bacterial flora through infusion of stool, known as a
fecal microbiota transplant Fecal microbiota transplant (FMT), also known as a stool transplant, is the process of transferring fecal bacteria and other microbes from a healthy individual into another individual. FMT is an effective treatment for ''Clostridioides diffici ...
, was first performed in 1958 employing retention enemas. Enemas remained the most common method until 1989, when alternative means of administration were developed. As of 2013, colonoscope implantation has been preferred over fecal enemas because by using the former method, the entire colon and ileum can be inoculated, but enemas reach only to the splenic flexure. * A patient unable to be fed otherwise can be
nourished Nutrition is the biochemical and physiological process by which an organism uses food to support its life. It provides organisms with nutrients, which can be metabolized to create energy and chemical structures. Failure to obtain sufficient nu ...
by an
enteral administration Enteral administration is food or drug administration via the human gastrointestinal tract. This contrasts with parenteral nutrition or drug administration (Greek ''para'', "besides" + ''enteros''), which occurs from routes outside the GI tract ...
of predigested foods, which is known as a
nutrient enema A nutrient enema, also known as feeding per rectum, rectal alimentation, or rectal feeding, is an enema administered with the intent of providing nutrition when normal eating is not possible. This treatment is ancient, dating back at least to the s ...
. This treatment is ancient, dating back at least to the second century CE when documented by Galen, and commonly used in the Middle Ages, remaining a common technique in 19th century, and as recently as 1941 the U. S. military's manual for hospital diets prescribes their use. Nutrient enemas have been superseded in modern medical care by tube feeding and
intravenous feeding Parenteral nutrition (PN) is the feeding of nutritional products to a person intravenously, bypassing the usual process of eating and digestion. The products are made by pharmaceutical compounding companies. The person receives a nutritional mix ...
. * Enemas have been used around the time of childbirth; however, there is no evidence for this practice and it is now discouraged.


Adverse effects

Improper administration of an enema can cause electrolyte imbalance (with repeated enemas) or ruptures to the bowel or rectal tissues resulting in internal bleeding. However, these occurrences are rare in healthy,
sober In cryptography, SOBER is a family of stream ciphers initially designed by Greg Rose of QUALCOMM Australia starting in 1997. The name is a contrived acronym for ''S''eventeen ''O''ctet ''B''yte ''E''nabled ''R''egister. Initially the cipher wa ...
adults. Internal bleeding or rupture may leave the individual exposed to infections from intestinal bacteria. Blood resulting from tears in the colon may not always be visible, but can be distinguished if the feces are unusually dark or have a red hue. If intestinal rupture is suspected, medical assistance should be obtained immediately. Frequent use of enemas can cause laxative dependency. The enema tube and solution may stimulate the vagus nerve, which may trigger an
arrhythmia Arrhythmias, also known as cardiac arrhythmias, heart arrhythmias, or dysrhythmias, are irregularities in the heartbeat, including when it is too fast or too slow. A resting heart rate that is too fast – above 100 beats per minute in adults ...
such as
bradycardia Bradycardia (also sinus bradycardia) is a slow resting heart rate, commonly under 60 beats per minute (BPM) as determined by an electrocardiogram. It is considered to be a normal heart rate during sleep, in young and healthy or elderly adults, a ...
. Enemas should not be used if there is an undiagnosed abdominal pain since the peristalsis of the bowel can cause an inflamed
appendix Appendix, or its plural form appendices, may refer to: __NOTOC__ In documents * Addendum, an addition made to a document by its author after its initial printing or publication * Bibliography, a systematic list of books and other works * Index (pub ...
to
rupture Rupture may refer to: General * Rupture (engineering), a failure of tough ductile materials loaded in tension Anatomy and medicine * Abdominal hernia, formerly referred to as "a rupture" * Achilles tendon rupture * Rupture of membranes, a "wate ...
. There are arguments both for and against colonic irrigation in people with
diverticulitis Diverticulitis, specifically colonic diverticulitis, is a gastrointestinal disease characterized by inflammation of abnormal pouches—diverticula—which can develop in the wall of the large intestine. Symptoms typically include lower abdominal ...
, ulcerative colitis,
Crohn's disease Crohn's disease is a type of inflammatory bowel disease (IBD) that may affect any segment of the gastrointestinal tract. Symptoms often include abdominal pain, diarrhea (which may be bloody if inflammation is severe), fever, abdominal distension ...
, severe or internal
hemorrhoids Hemorrhoids (or haemorrhoids), also known as piles, are vascular structures in the anal canal. In their normal state, they are cushions that help with stool control. They become a disease when swollen or inflamed; the unqualified term ''hemo ...
or tumors in the rectum or colon, and its usage is not recommended soon after bowel
surgery Surgery ''cheirourgikē'' (composed of χείρ, "hand", and ἔργον, "work"), via la, chirurgiae, meaning "hand work". is a medical specialty that uses operative manual and instrumental techniques on a person to investigate or treat a pat ...
(unless directed by one's health care provider). Regular treatments should be avoided by people with
heart disease Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels. CVD includes coronary artery diseases (CAD) such as angina and myocardial infarction (commonly known as a heart attack). Other CVDs include stroke, hea ...
or kidney failure. Colonics are inappropriate for people with bowel, rectal or anal pathologies where the pathology contributes to the risk of bowel perforation. Recent research has shown that ozone water, which is sometimes used in enemas, can immediately cause microscopic colitis. A recent case series of 11 patients with five deaths illustrated the danger of phosphate enemas in high-risk patients.


History


Etymology

''Enema'' entered the English language c. 1675 from Latin in which, in the 15th century, it was first used in the sense of a rectal injection, from Greek ἔνεμα (énema), "injection", itself from ἐνίηναι (enienai) "to send in, inject", from ἐν (en), "in" + ἱέναι (hienai), "to send, throw". ''Clyster'' entered the English language in the late 14th century from Old French or Latin, from Greek κλυστήρ (klyster), "syringe", itself from κλύζειν (klyzein), "to wash out", also spelled ''glister'' in the 18th century, is a generally archaic word used more particularly for enemas administered using a ''clyster syringe''.


Ancient and medieval


Africa

The first mention of the enema in medical literature is in the Ancient Egyptian Ebers Papyrus ( BCE). One of the many types of medical specialists was an Iri, the Shepherd of the Anus. Many medications were administered by enemas. There was a Keeper of the Royal Rectum who may have primarily been the pharaoh's enema maker. The god Thoth, according to Egyptian mythology, invented the enema. In parts of Africa the calabash gourd is used traditionally to administer enemas. On the Ivory Coast the narrow neck of the gourd filled with water is inserted the patient's rectum and the contents are then injected by means of an attendant's forcible oral inflation, or, alternatively, a patient may self-administer the enema by using suction to create a negative pressure in the gourd, placing a finger at the opening, and then upon anal insertion, removing the finger to allow atmospheric pressure to effect the flow. Along the upper Congo River an enema apparatus is made by making a hole in one end of the gourd for filling it, and using a resin to attach a hollow cane to the gourd's neck. The cane is inserted into the anus of the patient who is in a posture that allows gravity to effect infusion of the fluid.


Americas

The Olmec from their middle preclassic period (10th through 7th centuries BCE) through the Spanish Conquest used trance-inducing substances ceremonially, and these were ingested via, among other routes, enemas administered using jars. As further described below in religious rituals, the Maya in their late classic age (7th through 10th centuries CE) used enemas for, at least, ritual purposes, Mayan sculpture and ceramics from that period depicting scenes in which, injected by syringes made of gourd and clay, ritual hallucinogenic enemas were taken. In the Xibalban court of the God D, whose worship included ritual cult paraphernal, the Maya illustrated the use of a characteristic enema bulb syringe by female attendants administering clysters ritually. For combating illness and discomfort of the digestive tract, the Mayan also employed enemas, as documented during the colonial period, e.g., in the Florentine Codex. The indigenous peoples of North America employed tobacco smoke enemas to stimulate respiration, injecting the smoke using a rectal tube. A rubber bag connected with a conical nozzle, at an early period, was in use among the
indigenous peoples of South America The Indigenous peoples of South America or South American Indigenous peoples, are the pre-Colombian peoples of South America and their descendants. These peoples contrast with South Americans of European ancestry and those of African descent. ...
as an enema syringe, and the rubber enema bag with a connecting tube and ivory tip remained in use by them while in Europe a syringe was still the usual means for conducting an enema.


Asia

In Babylonia, by 600 BCE, enemas were in use, although it appears that initially they were in use because of a belief that the demon of disease would, by means of an enema, be driven out of the body.Friedenwald & Morrison, Part I:77 Babylonian and Assyrian tablets c. 600 BCE bear cuneiform inscriptions referring to enemas. In China, c. 200 CE, Zhang ZhongjingRedirected from Chang Chung-ching, the name used in the reference---> was the first to employ enemas. "Secure a large pig's bile and mix with a small quantity of vinegar. Insert a bamboo tube three or four inches long into the rectum and inject the mixture" are his directions, according to Wu Lien-teh. In India, in the fifth century BCE,
Sushruta Sushruta, or ''Suśruta'' (Sanskrit: सुश्रुत, IAST: , ) was an ancient Indian physician. The ''Sushruta Samhita'' (''Sushruta's Compendium''), a treatise ascribed to him, is one of the most important surviving ancient treatises on ...
enumerates the enema syringe among 121 surgical instruments described. Early Indian physicians' enema apparatus consisted of a tube of bamboo, ivory, or horn attached to the scrotum of a deer, goat, or ox. In Persia,
Avicenna Ibn Sina ( fa, ابن سینا; 980 – June 1037 CE), commonly known in the West as Avicenna (), was a Persian polymath who is regarded as one of the most significant physicians, astronomers, philosophers, and writers of the Islamic G ...
(980–1037 A. D.) is credited with the introduction of the "clyster-purse" or collapsible portion of an enema outfit made from ox skin or silk cloth and emptied by squeezing with the hands.


Europe

Hippocrates (460–370 BCE) frequently mentions enemas, e.g., "if the previous food which the patient has recently eaten should not have gone down, give an enema if the patient be strong and in the prime of life, but if he be weak, a suppository should be administered, should the bowels be not well moved on their own accord." In the first century BCE the Greek physician
Asclepiades of Bithynia Asclepiades ( el, Ἀσκληπιάδης; c. 129/124 BC – 40 BC), sometimes called Asclepiades of Bithynia or Asclepiades of Prusa, was a Greek physician born at Prusias-on-Sea in Bithynia in Anatolia and who flourished at Rome, where he pr ...
wrote "Treatment consists merely of three elements: drink, food, and the enema". Also, he contended that indigestion is caused by particles of food that are too big and his prescribed treatment was proper amounts of food and wine followed by an enema which would remove the improper food doing the damage. In the second century CE the Greek physician Soranus prescribed, among other
techniques Technique or techniques may refer to: Music * The Techniques, a Jamaican rocksteady vocal group of the 1960s *Technique (band), a British female synth pop band in the 1990s * ''Technique'' (album), by New Order, 1989 * ''Techniques'' (album), by M ...
, enemas as a safe abortion method, and the Greek philosopher Celsus recommended an enema of pearl barley in milk or rose oil with butter as a nutrient for those with dysentery and unable to eat, and also Galen mentions enemas in several contexts. In medieval times appear the first illustrations of enema equipment in the Western world, a clyster syringe consisting of a tube attached to a pump action bulb made of a pig bladder. A simple piston
syringe A syringe is a simple reciprocating pump consisting of a plunger (though in modern syringes, it is actually a piston) that fits tightly within a cylindrical tube called a barrel. The plunger can be linearly pulled and pushed along the inside ...
clyster was in use from the 15th through 19th centuries. This device had its rectal nozzle connected to a syringe with a plunger rather than to a bulb.


Modern western

Beginning in the 17th century enema apparatus was chiefly designed for self-administration at home and many were French as enemas enjoyed wide usage in France. In 1694
François Mauriceau François Mauriceau (1637 – 17 October 1709) was a French obstetrician. __TOC__ Life Born in Paris, he received his training in obstetrics at the Hôtel-Dieu. He was a leading obstetrician in 17th-century Europe — in 1668 he published, ...
in his early-modern treatise, ''The Diseases of Women with Child,'' records that both midwives and man-midwives commonly administered clysters to labouring mothers just prior to their delivery. Clysters were administered for symptoms of constipation and, with more questionable effectiveness, stomach aches and other illnesses. In 1753 an enema bag prepared from a pig's or beef's bladder attached to a tube was described by Johann Jacob Woyts as an alternative to a syringe. In the 18th century Europeans began emulating the indigenous peoples of North America's use of tobacco smoke enemas to resuscitate drowned people. Tobacco resuscitation kits consisting of a pair of bellows and a tube were provided by the Royal Humane Society of London and placed at various points along the Thames. Furthermore, these enemas came to be employed for headaches, respiratory failure, colds, hernias, abdominal cramps, typhoid fever, and cholera outbreaks. Clysters were a favourite medical treatment in the
bourgeoisie The bourgeoisie ( , ) is a social class, equivalent to the middle or upper middle class. They are distinguished from, and traditionally contrasted with, the proletariat by their affluence, and their great cultural and financial capital. They ...
and nobility of the Western world up to the 19th century. As medical knowledge was fairly limited at the time, purgative clysters were used for a wide variety of ailments, the foremost of which were
stomach ache Abdominal pain, also known as a stomach ache, is a symptom associated with both non-serious and serious medical issues. Common causes of pain in the abdomen include gastroenteritis and irritable bowel syndrome. About 15% of people have a m ...
s and constipation. According to the duc de Saint-Simon, clysters were so popular at the court of King Louis XIV of France that the duchess of Burgundy had her servant give her a clyster in front of the King (her modesty being preserved by an adequate posture) before going to the comedy. However, he also mentions the astonishment of the King and Mme de Maintenon that she should take it before them. In the 19th century many new types of enema administration equipment were devised. Devices allowing gravity to infuse the solution, like those mentioned above used by South American indigenous people and like the enema bag described by Johann Jacob Woyts, came into common use. These consist of a nozzle at the end of a hose which connects a reservoir, either a bucket or a rubber bag, which is filled with liquid and held or hung above the recipient. In the early 20th century the disposable microenema, a squeeze bottle, was invented by Charles Browne Fleet.


Society and culture


Alternative medicine


Relatively benign


= Colonic irrigation

= The term "colonic irrigation" is commonly used in gastroenterology to refer to the practice of introducing water through a colostomy or a surgically constructed conduit as a treatment for constipation. The Food and Drug Administration has ruled that colonic irrigation equipment is not approved for sale for the purpose of general well-being and has taken action against many distributors of this equipment, including a Warning Letter.


= Colon cleansing

= The same term is also used in
alternative medicine Alternative medicine is any practice that aims to achieve the healing effects of medicine despite lacking biological plausibility, testability, repeatability, or evidence from clinical trials. Complementary medicine (CM), complementary and alt ...
where it may involve the use of substances mixed with water in order to
detoxify Detoxification or detoxication (detox for short) is the physiological or medicinal removal of toxic substances from a living organism, including the human body, which is mainly carried out by the liver. Additionally, it can refer to the period o ...
the body. Practitioners believe the accumulation of fecal matter in the large intestine leads to ill health. This resurrects the old medical concept of ''autointoxication'' which was orthodox doctrine up to the end of the 19th century but which has now been discredited.


=Kellogg's enemas

= In the late 19th century Dr. John Harvey Kellogg made sure that the bowel of each and every patient was plied with water, from above and below. His favorite device was an enema machine ("just like one I saw in Germany") that could run fifteen gallons of water through a person's bowel in a matter of seconds. Every water enema was followed by a pint of yogurt—half was eaten, the other half was administered by enema "thus planting the protective germs where they are most needed and may render most effective service." The yogurt served to replace "the intestinal flora" of the bowel, creating what Kellogg claimed was a completely clean intestine.


Dangerous


= Bleach enemas

= Chlorine dioxide enemas have been fraudulently marketed as a medical treatment, primarily for
autism The autism spectrum, often referred to as just autism or in the context of a professional diagnosis autism spectrum disorder (ASD) or autism spectrum condition (ASC), is a neurodevelopmental condition (or conditions) characterized by difficulti ...
. This has resulted, for example, in a six-year-old boy needing to have his colon removed and a colostomy bag fitted, complaints to the FDA reporting life-threatening reactions, and even death. Proponents falsely claim that administering autistic children these enemas results in the expulsion of parasitic worms ("
rope worms "Rope worms" (or "ropeworms") is a pseudoscientific term for long thin pieces of damaged intestinal epithelium or other bowel content that have been misidentified as human parasitic worms. "Rope worms" were reported in 2013 in two self-publishe ...
"), which actually are fragments of damaged intestinal
epithelium Epithelium or epithelial tissue is one of the four basic types of animal tissue, along with connective tissue, muscle tissue and nervous tissue. It is a thin, continuous, protective layer of compactly packed cells with a little intercellul ...
that are misinterpreted as being human pathogens. Oral and rectal use of the solution has also been promoted as a cure for HIV, malaria, viral hepatitis,
influenza Influenza, commonly known as "the flu", is an infectious disease caused by influenza viruses. Symptoms range from mild to severe and often include fever, runny nose, sore throat, muscle pain, headache, coughing, and fatigue. These symptoms ...
,
common cold The common cold or the cold is a viral infectious disease of the upper respiratory tract that primarily affects the respiratory mucosa of the nose, throat, sinuses, and larynx. Signs and symptoms may appear fewer than two days after exposu ...
s, acne, cancer,
Parkinson's Parkinson's disease (PD), or simply Parkinson's, is a long-term degenerative disorder of the central nervous system that mainly affects the motor system. The symptoms usually emerge slowly, and as the disease worsens, non-motor symptoms becom ...
, and much more. Chlorine dioxide is a potent and toxic bleach that is relabeled for "medicinal purposes" to a variety of brand names including, but not limited, to MMS,
Miracle Mineral Supplement Miracle Mineral Supplement, often referred to as Miracle Mineral Solution, Master Mineral Solution, MMS or the CD protocol, is a branded name for an aqueous solution of chlorine dioxide, an industrial bleaching agent, that has been falsely ...
, and CD protocol. For oral use, the doses recommended on the labeling can cause nausea, vomiting, diarrhea, and potentially life-threatening dehydration. No clinical trials have been performed to test the health claims made for chlorine dioxide, which originate from former Scientologist Jim Humble in his 2006 self-published book, ''The Miracle Mineral Solution of the 21st Century'' and from anecdotal reports. The name MMS was coined by Humble. Sellers sometimes describe MMS as a water purifier so as to circumvent medical regulations. The
International Federation of Red Cross and Red Crescent Societies The International Federation of Red Cross and Red Crescent Societies (IFRC) is a worldwide humanitarian aid organization that reaches 160 million people each year through its 192-member National Societies. It acts before, during and after disas ...
rejected "in the strongest terms" reports by promoters of MMS that they had used the product to fight malaria.


= Coffee enemas

= Well documented as having no proven benefits and considered by medical authorities as rash and potentially dangerous is an enema of coffee. A coffee enema can cause numerous maladies including infections, sepsis (including
campylobacter ''Campylobacter'' (meaning "curved bacteria") is a genus of Gram-negative bacteria. ''Campylobacter'' typically appear comma- or s-shaped, and are motile. Some ''Campylobacter'' species can infect humans, sometimes causing campylobacteriosis, a d ...
sepsis), severe electrolyte imbalance, colitis, polymicrobial enteric sepsis,
proctocolitis Proctocolitis is a general term for inflammation of the rectum and colon. Signs and symptoms Cause Proctocolitis has many possible causes. Common infectious causes of proctocolitis include Chlamydia trachomatis, LGV (Lymphogranuloma venereum), ...
,
salmonella ''Salmonella'' is a genus of rod-shaped (bacillus) Gram-negative bacteria of the family Enterobacteriaceae. The two species of ''Salmonella'' are ''Salmonella enterica'' and ''Salmonella bongori''. ''S. enterica'' is the type species and is fur ...
, brain abscess, and heart failure, and deaths related to coffee enemas have been documented. Gerson therapy includes administering enemas of coffee, as well as of castor oil and sometimes of hydrogen peroxide or of ozone. Some proponents of alternative medicine have claimed that coffee enemas have an anti- cancer effect by "detoxifying" metabolic products of tumors but there is no medical scientific evidence to support this.


Recreational usage


Pleasure

Enjoyment of enemas is known as klismaphilia, which medically is classified as a paraphilia. A person with klismaphilia is a ''klismaphile''. Both women and men may enjoy sexual enema play, heterosexually and homosexually, experiencing
sexual arousal Sexual arousal (also known as sexual excitement) describes the physiological and psychological responses in preparation for sexual intercourse or when exposed to sexual stimuli. A number of physiological responses occur in the body and mind as ...
from enemas which they find gratifying or sensualAgnew, 1982 and which can be an auxiliary to, or even a substitute for, genital sexual activity. Klismaphiles may perceive pleasure from a large, water distended belly or the feeling of internal pressure. An enema fetish may include the sexual attraction to the equipment, processes, environments, situations, or scenarios, Klismaphiles can gain satisfaction of enemas through fantasies, by actually receiving or giving one, or through the process of eliminating steps to being administered one (e.g., under the pretence of being constipated). That some women use enemas while masturbating was documented by Alfred Kinsey in "Sexual Behavior in the Human Female." He stated, "There still reother masturbatory techniques which were regularly or occasionally employed by some 11 percent of the females in the sample ... enemas, and other anal insertions, ... were employed."


Other sexually related uses

Besides klismaphilia, the intrinsic enjoyment of enemas, there are other uses of enemas in sexual play., ''Klismaphilia'':76


= BDSM

= Enemas are sometimes used in sadomasochistic activities for erotic humiliation or for physical discomfort.


= Rectal douching

= Another sexual use for enemas is to empty the rectum as a prelude to other anal sexual activities such as
anal sex Anal sex or anal intercourse is generally the insertion and thrusting of the erect penis into a person's anus, or anus and rectum, for sexual pleasure.Sepages 270–271for anal sex information, anpage 118for information about the clitoris. ...
,
anilingus Anilingus (from the Latin ''anus'' + ''-lingus'', from ''lingere'', "to lick", variantly spelled "analingus") is the oral and anal sex act in which a person stimulates the anus of another by using the mouth, including lips, tongue, or teeth. I ...
, and pegging,Agnew, 2000:76 possibly reducing risk of infection. This is different from klismaphilia, in which the enema is enjoyed for itself and as a part of sexual arousal and gratification. Rectal douching is a common practice among people who take a receptive role in anal sex although rectal douching before anal sex may increase the risk of transferring HIV, hepatitis B, and other diseases.


Intoxication

Noting that deaths have been reported from alcohol poisoning via enemas, an
alcohol enema An alcohol enema, also known colloquially as butt-chugging or boofing, is the act of introducing alcohol (drug), alcohol into the rectum and Colon (anatomy), colon via the anus, i.e., as an enema. This method of alcohol consumption can be dangerous ...
can be used to very quickly instill alcohol into the bloodstream, absorbed through the membranes of the colon. However, great care must be taken as to the amount of alcohol used. Only a small amount is needed as the intestine absorbs the alcohol far more quickly than the stomach. Preceding an enema for administration of drugs or alcohol, a cleansing enema may first be used for cleaning the colon to help increase the rate of absorption.


Religious rituals

All across Mesoamerica ritual enemas were employed to consume psychoactive substances, e.g., balché,
alcohol Alcohol most commonly refers to: * Alcohol (chemistry), an organic compound in which a hydroxyl group is bound to a carbon atom * Alcohol (drug), an intoxicant found in alcoholic drinks Alcohol may also refer to: Chemicals * Ethanol, one of sev ...
, tobacco,
peyote The peyote (; ''Lophophora williamsii'' ) is a small, spineless cactus which contains psychoactive alkaloids, particularly mescaline. ''Peyote'' is a Spanish word derived from the Nahuatl (), meaning "caterpillar cocoon", from a root , "to gl ...
, and other
hallucinogenic drugs Hallucinogens are a large, diverse class of psychoactive drugs that can produce altered states of consciousness characterized by major alterations in thought, mood, and perception as well as other changes. Most hallucinogens can be categorize ...
and entheogens, most notably by the Maya, thus attaining more intense trance states more quickly, and Mayan classic-period sculpture and ceramics depict hallucinogenic enemas used in rituals. Some tribes continue the practice in the present day.; pp. 201 With historical roots in the Indian subcontinent, enemas in Ayurveda, called Basti or Vasti, form part of
Panchakarma Ayurveda () is an alternative medicine system with historical roots in the Indian subcontinent. The theory and practice of Ayurveda is pseudoscientific. Ayurveda is heavily practiced in India and Nepal, where around 80% of the population rep ...
procedure in which
herbal medicines Herbal medicine (also herbalism) is the study of pharmacognosy and the use of medicinal plants, which are a basis of traditional medicine. With worldwide research into pharmacology, some herbal medicines have been translated into modern remedies ...
are introduced rectally.


Punitive usage

Enemas have also been forcibly applied as a means of punishment. In the vastly influential Argentine text ''Facundo, or Civilization and Barbarism'', for example, Domingo Faustino Sarmiento describes the use of
pepper Pepper or peppers may refer to: Food and spice * Piperaceae or the pepper family, a large family of flowering plant ** Black pepper * ''Capsicum'' or pepper, a genus of flowering plants in the nightshade family Solanaceae ** Bell pepper ** Chili ...
and turpentine enemas by police forces as a way of discouraging political dissent in post-independence Argentina. Turpentine enemas are very harsh purgatives. In the
Guantanamo Bay Detention Camp The Guantanamo Bay detention camp ( es, Centro de detención de la bahía de Guantánamo) is a United States military prison located within Guantanamo Bay Naval Base, also referred to as Guantánamo, GTMO, and Gitmo (), on the coast of Guant ...
, the Senate Intelligence Committee report on CIA torture documented instances of enemas being used by the Central Intelligence Agency in order to ensure "total control" over detainees. Enemas, officials said, are uncomfortable and degrading, The CIA forced nutrient enema on detainees who attempted hunger strikes, documenting "With head lower than torso … sloshing up the large intestines … hatI infer is that you get a tube up as you can … We used the largest Ewal tube we had" wrote an officer, and "violent enemas" is how a detainee described what he received.


In arts and literature


Written literature

In the
Dionysus In ancient Greek religion and myth, Dionysus (; grc, Διόνυσος ) is the god of the grape-harvest, winemaking, orchards and fruit, vegetation, fertility, insanity, ritual madness, religious ecstasy, festivity, and theatre. The Romans ...
' satyr play ''Limos'', Silenus attempts to give an enema to Heracles. In Shakespeare's play ''
Othello ''Othello'' (full title: ''The Tragedy of Othello, the Moor of Venice'') is a tragedy written by William Shakespeare, probably in 1603, set in the contemporary Ottoman–Venetian War (1570–1573) fought for the control of the Island of Cypru ...
'' (Act II, Scene I) Iago says, "Yet again your fingers to your lips? would they were clyster-pipes for your sake!" In Cervantes' Don Quixote, a narrative to Sancho includes “The Knight of the Sun ... bound hand and foot ... was administered a clyster of snow water and sand that almost disracted him" In the 17th century, satirists made physicians a favorite target, resembling Molière's caricature whose prescription for anything was "clyster, bleed, purge," or "purge, bleed, clyster". In Molière's play
The Imaginary Invalid ''The Imaginary Invalid'', ''The Hypochondriac'', or ''The Would-Be Invalid'' ( French title ''Le Malade imaginaire'', ) is a three- act ''comédie-ballet'' by the French playwright Molière with dance sequences and musical interludes (H.495, H. ...
, Argan, a severe
hypochondriac Hypochondriasis or hypochondria is a condition in which a person is excessively and unduly worried about having a serious illness. An old concept, the meaning of hypochondria has repeatedly changed. It has been claimed that this debilitating cond ...
, is addicted to enemas as indicated by such lines as when Bĕralde asks, "Can't you be one moment without a purge?" In
George Orwell Eric Arthur Blair (25 June 1903 – 21 January 1950), better known by his pen name George Orwell, was an English novelist, essayist, journalist, and critic. His work is characterised by lucid prose, social criticism, opposition to totalitar ...
's novel '' Nineteen Eighty-Four'', the narrator notes, "Sexual intercourse was to be looked on as a slightly disgusting minor operation, like having an enema." In Grace Metalious's novel Peyton Place, the town doctor tells of "a young boy with the worst case of dehydration I ever saw. It came from getting too many enemas that he didn't need. Sex, with a capital S-E-X.". As a teenager, the boy enjoys receiving enemas from his mother. In
Flora Rheta Schreiber Flora Rheta Schreiber (April 24, 1918 – November 3, 1988)Special Collections, database. 2020.The Papers of Flora Rheta Schreiber 1916–1988" ''Lloyd Sealy Library''. New York: John Jay College of Criminal Justice. Retrieved 13 May 2020. was an A ...
's book
Sybil Sibyls were oracular women believed to possess prophetic powers in ancient Greece. Sybil or Sibyl may also refer to: Films * ''Sybil'' (1921 film) * ''Sybil'' (1976 film), a film starring Sally Field * ''Sybil'' (2007 film), a remake of the 19 ...
, Sybil's psychiatrist asks her "What's Mama been doing to you, dear?...I know she gave you the enemas." In Anne Roiphe's novel ''Torch Song'', Marjorie, not knowing how to otherwise address her dysphonia, reminisces on unhappy memories, one of which is her German nurse inflicting on her painful enemas. In Anne Sexton's poem "Cripples And Other Stories", is the couplet "Oh the enemas of childhood, reeking of outhouses and shame!"


Film

In '' The Right Stuff'', during flight training astronaut Alan Shepard retains a barium enema, given two floors away from a toilet, embarrassedly riding a public elevator wearing a
hospital gown A hospital gown, sometimes called a johnny gown or johnny, especially in Canada and New England, is "a long loose piece of clothing worn in a hospital by someone doing or having an operation". It can be used as clothing for bedridden patients. Ut ...
and holding the enema bag with its tip still inserted in him. '' Water Power'' is a film loosely based on the real-life exploits of
Michael H. Kenyon Michael Hubert Kenyon, (born c. 1944Baumann, Edward (June 5, 1975). Bond set for enema suspect. ''Chicago Tribune'' in Elgin, Illinois) also known as the "Illinois Enema Bandit", is an American criminal. He pleaded guilty to a decade-long series ...
, an
American American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, pe ...
criminal In ordinary language, a crime is an unlawful act punishable by a state or other authority. The term ''crime'' does not, in modern criminal law, have any simple and universally accepted definition,Farmer, Lindsay: "Crime, definitions of", in Can ...
who pleaded guilty to a decade-long series of
armed robberies Robbery is the crime of taking or attempting to take anything of value by force, threat of force, or by use of fear. According to common law, robbery is defined as taking the property of another, with the intent to permanently deprive the perso ...
of female victims, some of which involved
sexual assault Sexual assault is an act in which one intentionally sexually touches another person without that person's consent, or coerces or physically forces a person to engage in a sexual act against their will. It is a form of sexual violence, which ...
s in which he would give them enemas. In ''
Sybil Sibyls were oracular women believed to possess prophetic powers in ancient Greece. Sybil or Sibyl may also refer to: Films * ''Sybil'' (1921 film) * ''Sybil'' (1976 film), a film starring Sally Field * ''Sybil'' (2007 film), a remake of the 19 ...
'', Sybil's psychiatrist, while having taken her for a picnic in the country, heard her re-experience, among other things, her mother having bound her with a broom handle on the kitchen table and suspended her by her feet from the hanging light, in preparation for forcing her to take an enema.


Song

The lyrics of
Frank Zappa Frank Vincent Zappa (December 21, 1940 – December 4, 1993) was an American musician, composer, and bandleader. His work is characterized by wikt:nonconformity, nonconformity, Free improvisation, free-form improvisation, sound experimen ...
's song ''The Illinois Enema Bandit'' are concerned with
Michael H. Kenyon Michael Hubert Kenyon, (born c. 1944Baumann, Edward (June 5, 1975). Bond set for enema suspect. ''Chicago Tribune'' in Elgin, Illinois) also known as the "Illinois Enema Bandit", is an American criminal. He pleaded guilty to a decade-long series ...
's
sexual assault Sexual assault is an act in which one intentionally sexually touches another person without that person's consent, or coerces or physically forces a person to engage in a sexual act against their will. It is a form of sexual violence, which ...
s which included administering involuntary enemas.


Monument

A brass statue of a syringe enema bulb held aloft by three cherubs stands in front of the "Mashuk" spa in the settlement of
Zheleznovodsk Zheleznovodsk (russian: Железново́дск) is a town in Stavropol Krai, Russia. Population: Etymology The name of the town literally means ''iron-water-place'', as the mineral waters springing from the earth in Zheleznovodsk were belie ...
in Russia. Inspired by the 15th century Renaissance painter Botticelli, it was created by a local artist who commented that "An enema is an unpleasant procedure as many of us may know. But when cherubs do it, it's all right." When unveiled on 19 June 2008, posted on one of the spa's wall was a banner declaring "Let's beat constipation and sloppiness with enemas." The spa lying in the Caucasus Mountains region, known for dozens of spas that routinely treat digestive and other complaints with enemas of mineral spring water, the director commented "An enema is almost a symbol of our region." It is the only known monument to the enema.


See also

*
Alcohol enema An alcohol enema, also known colloquially as butt-chugging or boofing, is the act of introducing alcohol (drug), alcohol into the rectum and Colon (anatomy), colon via the anus, i.e., as an enema. This method of alcohol consumption can be dangerous ...
* Bowel management * Coffee enema *
Colon cleansing Colon cleansing, also known as colon therapy, or colon hydrotherapy, or a colonic, or colonic irrigation encompasses a number of alternative medical therapies claimed to remove unspecified toxins from the colon and intestinal tract by remov ...
* Dry enema *
Fecal microbiota transplant Fecal microbiota transplant (FMT), also known as a stool transplant, is the process of transferring fecal bacteria and other microbes from a healthy individual into another individual. FMT is an effective treatment for ''Clostridioides diffici ...
* Klismaphilia *
Murphy drip A Murphy drip is a rectal infusion apparatus to administer the medical procedure of proctoclysis, also known as rectoclysis. During the procedure, an end of the Murphy drip is inserted into the rectum and large quantities of liquid are infused ...
*
Nutrient enema A nutrient enema, also known as feeding per rectum, rectal alimentation, or rectal feeding, is an enema administered with the intent of providing nutrition when normal eating is not possible. This treatment is ancient, dating back at least to the s ...
*
Rectal douching Rectal douching is the act of rinsing the rectum with intent to clean it. An instance of this rinsing or a tool used to perform the rinse may be called a rectal douche. Uses Rectal douching is a hygienic practice to clean the rectum to void har ...
* Tobacco smoke enema * Transanal irrigation


References

Sources * * * * * * * * *


External links

{{authority control Alternative medicine Anal eroticism Anus BDSM equipment Constipation Digestive system Dosage forms Drug delivery devices Drugs acting on the gastrointestinal system and metabolism Evidence-based medicine Gastroenterology Health care Large intestine Laxatives Medical anthropology Rectum Routes of administration Self-care Sexual health Torture