Clotiapine (Entumine) is an
atypical antipsychotic of the
dibenzothiazepine
Dibenzothiazepines are chemical compounds which are derivatives of thiazepine with two benzene rings.
Examples include quetiapine, tianeptine, and metiapine
Metiapine is a typical antipsychotic medication of the dibenzothiazepine group. There ...
chemical class Chemical classification systems attempt to classify elements or compounds according to certain chemical functional or structural properties. Whereas the structural properties are largely intrinsic, functional properties and the derived classificat ...
.
It was first introduced in a few European countries (namely,
Belgium,
Italy,
Spain and
Switzerland
). Swiss law does not designate a ''capital'' as such, but the federal parliament and government are installed in Bern, while other federal institutions, such as the federal courts, are in other cities (Bellinzona, Lausanne, Luzern, Neuchâtel ...
),
Argentina,
Taiwan and
Israel in 1970.
[
Some sources regard clotiapine as a typical antipsychotic rather than atypical due to its high incidence of ]extrapyramidal side effects
Extrapyramidal symptoms (EPS) are symptoms that are archetypically associated with the extrapyramidal system of the brain's cerebral cortex. When such symptoms are caused by medications or other drugs, they are also known as extrapyramidal side ...
compared to the atypicals like clozapine and quetiapine, to which it is structurally related.systematic review
A systematic review is a Literature review, scholarly synthesis of the evidence on a clearly presented topic using critical methods to identify, define and assess research on the topic. A systematic review extracts and interprets data from publ ...
compared clotiapine with other antipsychotic drugs:
References
Atypical antipsychotics
Piperazines
Dibenzothiazepines
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