Clinatec
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Clinatec is a
biomedical Biomedicine (also referred to as Western medicine, mainstream medicine or conventional medicine)
research center based at the
Polygone Scientifique The Polygone Scientifique (en: Scientific Polygon) is a neighborhood of the city of Grenoble in France. It includes a significant number of research centers in a presque-isle between Isère (river), Isère and Drac (river), Drac. History Polygo ...
in Grenoble. Doctors, biologists and micro- and nanotechnology experts work side by side at the 6,000 m2 facility. Around a hundred researchers and employees work at the center. When it opened at the end of 2011, it was hailed as the first center of its kind in the world. With six hospital rooms, cutting-edge medical imaging equipment and an operating suite, Clinatec was developed by the Research Division of the CEA (French Alternative Energies and Atomic Energy Commission), Grenoble-Alpes University Hospital (CHU), Inserm and the Université Grenoble Alpes. The primary focus is on
cancer Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal b ...
,
neurodegenerative diseases A neurodegenerative disease is caused by the progressive loss of structure or function of neurons, in the process known as neurodegeneration. Such neuronal damage may ultimately involve cell death. Neurodegenerative diseases include amyotrophic ...
and
disability Disability is the experience of any condition that makes it more difficult for a person to do certain activities or have equitable access within a given society. Disabilities may be Cognitive disability, cognitive, Developmental disability, dev ...
.


Background

Professor
Alim Louis Benabid Alim Louis Benabid is a French-Algerian emeritus professor, neurosurgeon and member of the French Academy of Sciences, who has had a global impact in the development of deep brain stimulation (DBS) for Parkinson's disease and other movement disorde ...
and Jean Therme first met back in 2006. Alim Louis Benabid is a neurosurgeon. Together with Professor Pierre Pollak, he developed a new treatment for
Parkinson's disease Parkinson's disease (PD), or simply Parkinson's, is a long-term degenerative disorder of the central nervous system that mainly affects the motor system. The symptoms usually emerge slowly, and as the disease worsens, non-motor symptoms becom ...
, deep brain stimulation. His work received recognition in 2014 with the Lasker Award and in 2016 with the European Inventor Award. Jean Therme is Director of Technological Research at CEA Grenoble. He has worked tirelessly to make Grenoble a key center of expertise in electronics and micro- and nanotechnology, and to encourage close collaboration between the worlds of research and industry. Both men were convinced that millions of lives could be transformed by merging medical research and technology R&D. They agreed that the way to achieve this would be to bring together doctors, researchers, biologists, engineers, robotics engineers, mathematicians and knowledge engineers to work at a single site. In 2010–11, the 6,000 m2 building was built and equipped. In 2013, the first patient was admitted to the center, in relation to the "Protool" clinical trial coordinated by Professor Berger. For the first time, it was possible to use non-invasive procedures to explore regions of the brain that had hitherto been inaccessible. The exciting prospects opened up by this technology, the result of the coupling of technology developed at CEA-Leti with the clinical approach taken by researchers at Grenoble-Alpes University Hospital (CHU), Inserm and the Université Grenoble Alpes, led to setting up the MedPrint start-up, which won an I-lab award in 2015. In 2014, Clinatec launched a campaign to raise 30 million euros in order to develop a number of projects, including: *the Brain Computer Interface (BCI) project aiming to prove that a quadriplegic patient can drive neuroprosthetic effectors with multiple degrees of freedom, such as an exoskeleton, based on decoding cortical signals (ElectroCorticoGrams) measured by a Wimagine implant, and can do this through training to make the most of their cerebral plasticity, *and the Near InfraRed (NIR) project aiming to demonstrate that near-infrared light can have neuro-protective effects in treating Parkinson's disease.


Founding Members

Clinatec is the outcome of a solid partnership between the CEA (French Alternative Energies and Atomic Energy Commission), Grenoble-Alpes University Hospital (CHU), Inserm and the Université Grenoble Alpes.


The clinatec endowment fund

The Clinatec
endowment fund A financial endowment is a legal structure for managing, and in many cases indefinitely perpetuating, a pool of financial, real estate, or other investments for a specific purpose according to the will of its founders and donors. Endowments are of ...
was set up in 2014. A sponsorship campaign has been launched, aiming to raise 30 million euros by 2018.


Awards


Lasker Award

Professor
Alim Louis Benabid Alim Louis Benabid is a French-Algerian emeritus professor, neurosurgeon and member of the French Academy of Sciences, who has had a global impact in the development of deep brain stimulation (DBS) for Parkinson's disease and other movement disorde ...
, Clinatec's founder and chairman of the board, member of the
French Academy of Sciences The French Academy of Sciences (French: ''Académie des sciences'') is a learned society, founded in 1666 by Louis XIV of France, Louis XIV at the suggestion of Jean-Baptiste Colbert, to encourage and protect the spirit of French Scientific me ...
, is one of the joint winners of the prestigious Albert-Lasker Award for clinical research awarded by the Albert and Mary Lasker Foundation in New York. Professors Alim-Louis Benabid and Mahlon R. Delong of Emory University received awards for their contributions to the development of deep brain stimulation. The technique consists in stimulating the subthalamic nucleus to inhibit tremors and restore motor function in patients with Parkinson's disease and from complications caused by
Levodopa -DOPA, also known as levodopa and -3,4-dihydroxyphenylalanine, is an amino acid that is made and used as part of the normal biology of some plants and animals, including humans. Humans, as well as a portion of the other animals that utilize -DOPA ...
, a drug widely used in treating the disease.


Breakthrough Prize in Life Sciences

Set up in 2013 by
Mark Zuckerberg Mark Elliot Zuckerberg (; born ) is an American business magnate, internet entrepreneur, and philanthropist. He is known for co-founding the social media website Facebook and its parent company Meta Platforms (formerly Facebook, Inc.), o ...
and Priscilla Chan of
Facebook Facebook is an online social media and social networking service owned by American company Meta Platforms. Founded in 2004 by Mark Zuckerberg with fellow Harvard College students and roommates Eduardo Saverin, Andrew McCollum, Dustin M ...
, Sergey Brin, founder of
Google Google LLC () is an American multinational technology company focusing on search engine technology, online advertising, cloud computing, computer software, quantum computing, e-commerce, artificial intelligence, and consumer electronics. ...
, and Yuri Milner and Anne Wojcicki, the founders of
23andMe 23andMe Holding Co. is a publicly held personal genomics and biotechnology company based in South San Francisco, California. It is best known for providing a direct-to-consumer genetic testing service in which customers provide a saliva sample t ...
, the Breakthrough Prize in Life Sciences is awarded to researchers whose work extends human life expectancy. Professor
Alim Louis Benabid Alim Louis Benabid is a French-Algerian emeritus professor, neurosurgeon and member of the French Academy of Sciences, who has had a global impact in the development of deep brain stimulation (DBS) for Parkinson's disease and other movement disorde ...
was awarded the prize in 2015 for the development of deep brain stimulation, a technique which has revolutionized the treatment of
Parkinson's disease Parkinson's disease (PD), or simply Parkinson's, is a long-term degenerative disorder of the central nervous system that mainly affects the motor system. The symptoms usually emerge slowly, and as the disease worsens, non-motor symptoms becom ...
.


European Inventor Award 2016

On June 9, 2016, Professor
Alim Louis Benabid Alim Louis Benabid is a French-Algerian emeritus professor, neurosurgeon and member of the French Academy of Sciences, who has had a global impact in the development of deep brain stimulation (DBS) for Parkinson's disease and other movement disorde ...
received the European Inventor Award 2016 for his work on deep brain stimulation. The technique, now used all over the world, has radically transformed the lives of more than 150,000 people with Parkinson's disease, and significantly improved their quality of life.


Media interest

In July 2012,
Philippe Pozzo di Borgo Philippe Pozzo di Borgo (born 14 February 1951) is a Corsican French businessman who is the Director of Pommery and was the owner of an inherited historic ''hôtel particulier'' in Paris used as a function hall. Biography Philippe is the seco ...
, rendered quadriplegic following an accident and the man whose story was the inspiration for the French film
Intouchables ''The Intouchables'' (french: Intouchables, ), also known as ''Untouchable'' in the UK and Ireland, is a 2011 French Buddy film, buddy comedy-drama film written and directed by Olivier Nakache & Éric Toledano. It stars François Cluzet and Omar ...
, visited Clinatec with a group of local journalists. He expressed his confidence in and admiration for this research program in a report aired on regional news channel,
France 3 Alpes France 3 Alpes is one France 3's regional broadcasting services to people in the Rhône-Alpes region. It was launched as ORTF Rhône-Alpes in 1968. It is headquartered in La Tronche. The service is also one of 2 services to be broadcast to people l ...
Hero's Intouchables visiting Clinatec
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See also

*
Brain computer interface A brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals. It is located in the head, usually close to the sensory organs for senses such as vision. It is the most complex organ in a ve ...
*
Minatec Minatec (initially called the Micro and Nanotechnology Innovation Centre) is a research complex specializing in micro-nano technologies in Grenoble, France. The centre was inaugurated in June 2006 by François Loos, French Minister Delegate ...


References


External links


Clinatec official website
(English)
Clinatec official website
(French) {{Authority control Neuroscience research centers in France Nanotechnology Grenoble Alpes University Science and technology in Grenoble Research and development