Clemens Van Blitterswijk
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Clemens A. van Blitterswijk (1957,
The Hague The Hague ( ; nl, Den Haag or ) is a city and municipality of the Netherlands, situated on the west coast facing the North Sea. The Hague is the country's administrative centre and its seat of government, and while the official capital of ...
) is a Dutch tissue engineer who contributed to the use of biomaterials to heal bone injuries, especially using osteoinductive ceramics. In collaboration with Jan de Boer and others, he has contributed to screening microtextures to study cell-biomaterial interactions, an approach termed
materiomics Materiomics is the holistic study of material systems. Materiomics examines links between physicochemical material properties and material characteristics and function. The focus of materiomics is system functionality and behavior, rather than a pie ...
.


Career

Blitterswijk graduated from a bachelor in cell biology at
Leiden University Leiden University (abbreviated as ''LEI''; nl, Universiteit Leiden) is a Public university, public research university in Leiden, Netherlands. The university was founded as a Protestant university in 1575 by William the Silent, William, Prince o ...
and defended his PhD thesis in 1985 at the same university on artificial ceramic middle ear implants under the supervision of Professor Jan Grote and
Klaas de Groot Klaas de Groot (born 3 November 1940, Bergen, Limburg) is Emeritus Professor at the Tissue Engineering Group at the University of Twente. In the past he also worked as a visiting scientist at the UCLA bone research laboratory. His work has focuse ...
, for which he was awarded the Jean Leray young scientist award from the
European Society for Biomaterials The European Society for Biomaterials (ESB) is a non-profit organisation that encourages research and spread of information regarding research and uses of biomaterials. Founded in March 1976, became a member of the International Union of Societie ...
in 1987. From 1985 to 1996, he worked on hydroxyapatite biomaterials for middle ear implants under the mentorship of Jan Grote and Klaas De Groot at
Leiden University Leiden University (abbreviated as ''LEI''; nl, Universiteit Leiden) is a Public university, public research university in Leiden, Netherlands. The university was founded as a Protestant university in 1575 by William the Silent, William, Prince o ...
. In 1996, he left
Leiden University Leiden University (abbreviated as ''LEI''; nl, Universiteit Leiden) is a Public university, public research university in Leiden, Netherlands. The university was founded as a Protestant university in 1575 by William the Silent, William, Prince o ...
and co-founded, together with Klaas De Groot, IsoTis BV, a life sciences company focused on bone biomaterials and tissue engineering. In 1997, he became a professor at
University of Twente The University of Twente (Dutch: ''Universiteit Twente''; , abbr. ) is a public technical university located in Enschede, Netherlands. The university has been placed in the top 170 universities in the world by multiple central ranking tables. ...
. Later, he was appointed director of the University of Twente's MIRA Institute for Biomedical Technology and Technical Medicine institute (the institute no longer exists). In collaboration with Jan de Boer, Hemant Unadkat, and Dimitrios Stamatialis, he contributed to the development of a high-throughput assay to design and select micrometer-scale surface textures that could enhance specific biological functions (TopoChip). In 2012, he became a partner of the Life Science Partner (LSP) private investment firm where he invests in private companies and startups related to healthcare innovations. In 2014, he became a distinguished professor at
Maastricht University Maastricht University (abbreviated as UM; nl, Universiteit Maastricht) is a public research university in Maastricht, Netherlands. Founded in 1976, it is the second youngest of the thirteen Dutch universities. In 2021, 22,383 students studied at ...
. Until 2018, he was the director and department chair at the MERLN Institute at
Maastricht University Maastricht University (abbreviated as UM; nl, Universiteit Maastricht) is a public research university in Maastricht, Netherlands. Founded in 1976, it is the second youngest of the thirteen Dutch universities. In 2021, 22,383 students studied at ...
. In 2015, he was awarded an ERC Advanced grant that aimed at developing microfabricated and
microfluidic Microfluidics refers to the behavior, precise control, and manipulation of fluids that are geometrically constrained to a small scale (typically sub-millimeter) at which surface forces dominate volumetric forces. It is a multidisciplinary field tha ...
cell culture platforms for improving organoids. The conception of this grant application and the research relative to it were done by several principal investigators at Maastricht University.


Valorization

He has served as CEO of IsoTis., a company that underwent an
Initial Public Offering An initial public offering (IPO) or stock launch is a public offering in which shares of a company are sold to institutional investors and usually also to retail (individual) investors. An IPO is typically underwritten by one or more investment ...
and was subsequently acquired by Integra LifeSciences. In 2018, he became the chairman of the board of directors of Kuros Biosciences.


Teaching

Blitterswijk has been the official supervisor of over 80 PhD candidates who, in their large majority, have worked in the laboratories of other faculty members. He has participated as an editor of four textbooks, including one dedicated to tissue engineering.


Awards

* Jean Leray award in 1989 for the work in his PhD thesis *Professor de Kleijn award in 1989 for the work in his PhD thesis *George Winter senior scientist award in 1997 * Federa award in 2012 *"Most entrepreneurial scientist" award in 2012 *Career Achievement award of the EU Chapter of the Tissue Engineering and Regenerative Medicine International Society in 2013 * Huibregtsen award in 2015 * ESB Klaas de Groot award in 2021


Ten outstanding publications as a co-author or corresponding author

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References


External links

* Introduction to Professor van Blitterswijk: https://www.youtube.com/watch?v=HjYBwYS1eI0 * TEDx talk: https://www.youtube.com/watch?v=BR9oAyVldl0 {{DEFAULTSORT:Blitterswijk, Clemens van 1957 births Living people Dutch bioengineers Engineers from The Hague Academic staff of the University of Twente Members of the Royal Netherlands Academy of Arts and Sciences