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A chemical peel is a technique used to improve and smooth the texture of the
skin Skin is the layer of usually soft, flexible outer tissue covering the body of a vertebrate animal, with three main functions: protection, regulation, and sensation. Other animal coverings, such as the arthropod exoskeleton, have different de ...
. Facial skin is mostly treated, and scarring can be improved. Chemical peels are intended to remove the outermost layers of the skin. To accomplish this task, the chosen peel solution induces a controlled injury to the skin. Resulting wound healing processes begin to regenerate new tissues. The dead skin eventually peels off.Chemical Peels , The Ageing Skin
/ref> The regenerated skin is usually smoother and less wrinkled than the old skin. Some types of chemical peels can be purchased and administered without a medical license, however people are advised to seek professional help from a
dermatologist Dermatology is the branch of medicine dealing with the skin.''Random House Webster's Unabridged Dictionary.'' Random House, Inc. 2001. Page 537. . It is a speciality with both medical and surgical aspects. A dermatologist is a specialist medica ...
or
plastic surgeon Plastic surgery is a surgical specialty involving the restoration, reconstruction or alteration of the human body. It can be divided into two main categories: reconstructive surgery and cosmetic surgery. Reconstructive surgery includes craniof ...
on a specific type of chemical peel before a procedure is performed.


Types

There are several types of chemical peels.


''α''-hydroxy acid peels

Alpha hydroxy acid α-Hydroxy acids, or alpha hydroxy acids (AHAs), are a class of chemical compounds that consist of a carboxylic acid with a hydroxyl group substituent on the adjacent (alpha) carbon. Prominent examples are glycolic acid, lactic acid, mandelic ac ...
s (AHAs) are naturally occurring carboxylic acids such as
glycolic acid Glycolic acid (or hydroxyacetic acid; chemical formula HOCH2CO2H) is a colorless, odorless and hygroscopic crystalline solid, highly soluble in water. It is used in various skin-care products. Glycolic acid is widespread in nature. A glycolate (s ...
, a natural constituent of sugar cane juice, and
lactic acid Lactic acid is an organic acid. It has a molecular formula . It is white in the solid state and it is miscible with water. When in the dissolved state, it forms a colorless solution. Production includes both artificial synthesis as well as nat ...
, found in sour milk and tomato juice as well as being produced endogenously during normal
metabolism Metabolism (, from el, μεταβολή ''metabolē'', "change") is the set of life-sustaining chemical reactions in organisms. The three main functions of metabolism are: the conversion of the energy in food to energy available to run c ...
and exercise. This is the mildest of the peel formulas and produces light peels for treatment of fine wrinkles, areas of dryness, uneven pigmentation and acne. Alpha hydroxy acids can also be mixed with facial washes, serums or creams in lesser concentrations as part of a daily skin-care regimen to improve the skin's texture. There are five usual fruit acids:
citric acid Citric acid is an organic compound with the chemical formula HOC(CO2H)(CH2CO2H)2. It is a colorless weak organic acid. It occurs naturally in citrus fruits. In biochemistry, it is an intermediate in the citric acid cycle, which occurs in ...
,
glycolic acid Glycolic acid (or hydroxyacetic acid; chemical formula HOCH2CO2H) is a colorless, odorless and hygroscopic crystalline solid, highly soluble in water. It is used in various skin-care products. Glycolic acid is widespread in nature. A glycolate (s ...
,
lactic acid Lactic acid is an organic acid. It has a molecular formula . It is white in the solid state and it is miscible with water. When in the dissolved state, it forms a colorless solution. Production includes both artificial synthesis as well as nat ...
,
malic acid Malic acid is an organic compound with the molecular formula . It is a dicarboxylic acid that is made by all living organisms, contributes to the sour taste of fruits, and is used as a food additive. Malic acid has two stereoisomeric forms ( ...
and
tartaric acid Tartaric acid is a white, crystalline organic acid that occurs naturally in many fruits, most notably in grapes, but also in bananas, tamarinds, and citrus. Its salt, potassium bitartrate, commonly known as cream of tartar, develops naturally ...
. Many other alpha hydroxy acids exist and are used. AHA peels are not indicated for treating wrinkles. AHA peels may cause stinging, skin redness, mild skin irritation, and dryness. Higher pH levels and lower percentages of hydroxy acids are commonly used as home peels. These will not work as quickly as an in-office procedure, but can be economical for many people.


β hydroxy acid peels

Salicylic acid is a beta hydroxy acid. It is antibacterial (mostly bacteriostatic, except in high concentrations when it is more frequently bactericidal) and antiinflammatory and, as a result, works well for acne. Salicylic acid also has the ability to reduce the spots and bumps associated with acne. It is becoming common for
beta hydroxy acid A beta hydroxy acid or β-hydroxy acid (BHA) is an organic compound that contains a carboxylic acid functional group and hydroxy functional group separated by ''two'' carbon atoms. They are closely related to alpha hydroxy acids, in which the tw ...
(BHA) peels to be used instead of the stronger alpha hydroxy acid (AHA) peels due to BHA's being oil soluble. Studies show that BHA peels control sebum excretion, acne as well as remove dead skin cells to a certain extent better than AHAs due to AHAs only working on the surface of the skin.


Retinoic acid peel

Retinoic acid Retinoic acid (used simplified here for all-''trans''-retinoic acid) is a metabolite of vitamin A1 (all-''trans''-retinol) that mediates the functions of vitamin A1 required for growth and development. All-''trans''-retinoic acid is required in ...
is a retinoid. This type of facial peel is also performed in the office of a plastic surgeon, oral and maxillofacial surgeon, or a dermatologist in a
medical spa A day spa is a business that provides a variety of services for the purpose of improving health, beauty, and relaxation through Body treatment, personal care treatments such as massages and facials. The number of day spas in the US almost do ...
setting. This is a deeper peel than the beta hydroxy acid peel and is used to remove scars as well as wrinkles and pigmentation problems. It is usually performed in conjunction with a Jessner; which is performed right before, in order to open up the skin, so the retinoic acid can penetrate on a deeper level. The client leaves with the chemical peel solution on their face. The peeling process takes place on the third day. More dramatic changes to the skin require multiple peels over time.


Phenol-croton oil peel

A
phenol Phenol (also called carbolic acid) is an aromatic organic compound with the molecular formula . It is a white crystalline solid that is volatile. The molecule consists of a phenyl group () bonded to a hydroxy group (). Mildly acidic, it ...
- croton oil is a type of chemical peel. The term "phenol-croton oil peel" has replaced the vague term "phenol peel" in medical literature. It was originally used on a clandestine basis by early Hollywood stars in the 1920s and was incorporated into mainstream practice in the 1960s by Thomas Baker. The active ingredient is croton oil, which causes an intense caustic exfoliating reaction in the skin.


History

Resurfacing and restoring skin with chemical peel was introduced in the second half of the 19th century by the Austrian dermatologist
Ferdinand Ritter von Hebra Ferdinand Karl Franz Schwarzmann, Ritter von Hebra (7 September 1816, in Brno, Moravia – 5 August 1880 in Vienna, Austria-Hungary) was an Austrian physician and dermatologist known as the founder of the New Vienna School of Dermatology, an ...
(1816–1880), founder of the Vienna School of Dermatology. He used exfoliative agents, like phenol, croton oil, nitric acid in various cautious combination for treating freckles and skin irregularities.


Complications

The deeper the peel, the more complications that can arise. Professional strength chemical peels are typically administered by certified dermatologists or licensed estheticians. Professional peels and lower-concentration DIY home peel kits can pose health risks, including injury and scarring of the skin. Possible complications include photosensitivity, prolonged
erythema Erythema (from the Greek , meaning red) is redness of the skin or mucous membranes, caused by hyperemia (increased blood flow) in superficial capillaries. It occurs with any skin injury, infection, or inflammation. Examples of erythema not asso ...
, pigmentary changes,
milia A milium (''plural'' milia), also called a milk spot or an oil seed, is a clog of the eccrine sweat gland. It is a keratin-filled cyst that can appear just under the epidermis or on the roof of the mouth.Freedberg, et al. (2003). ''Fitzpatrick' ...
, skin atrophy, and textural changes. Many individuals report professional chemical peels leave a minor yellowish tinge on their skin due to the retinol elements in the peel. This is expected to last 2–3 hours maximum. Varying mild to moderate redness after the procedure is expected.


Anesthesia

Light chemical peels like AHA and BHA are usually done in medical offices or Med Spas. There is minimal
discomfort Comfort (or being comfortable'')'' is a sense of physical or psychological ease, often characterized as a lack of hardship. Persons who are lacking in comfort are uncomfortable, or experiencing discomfort. A degree of psychological comfort c ...
so usually no
anesthetic An anesthetic (American English) or anaesthetic (British English; see spelling differences) is a drug used to induce anesthesia ⁠— ⁠in other words, to result in a temporary loss of sensation or awareness. They may be divided into two ...
is given because the patient feels only a slight stinging when the
solution Solution may refer to: * Solution (chemistry), a mixture where one substance is dissolved in another * Solution (equation), in mathematics ** Numerical solution, in numerical analysis, approximate solutions within specified error bounds * Soluti ...
is applied. Medium peels such as
trichloroacetic acid Trichloroacetic acid (TCA; TCAA; also known as trichloroethanoic acid) is an analogue of acetic acid in which the three hydrogen atoms of the methyl group have all been replaced by chlorine atoms. Salts and esters of trichloroacetic acid are calle ...
(TCA) are also performed in the doctor’s office or in an
ambulatory surgery center Outpatient surgery, also known as ambulatory surgery, day surgery, day case surgery, or same-day surgery, is surgery that does not require an overnight hospital stay.The International Association for Ambulatory Surgery (IAAS) would not consider a ...
as an outpatient procedure and can cause more discomfort. Frequently, the combination of a
tranquilizer A tranquilizer is a drug that is designed for the treatment of anxiety, fear, tension, agitation, and disturbances of the mind, specifically to reduce states of anxiety and tension. Etymology Tranquilizer, as a term, was first used by F.F. Yonk ...
such as
diazepam Diazepam, first marketed as Valium, is a medicine of the benzodiazepine family that acts as an anxiolytic. It is commonly used to treat a range of conditions, including anxiety, seizures, alcohol withdrawal syndrome, muscle spasms, insomnia, ...
and an oral analgesic is administered. TCA peels often do not require anesthesia even if the solution itself has - at the contrary of phenol - no numbing effect on the skin. The
patient A patient is any recipient of health care services that are performed by healthcare professionals. The patient is most often ill or injured and in need of treatment by a physician, nurse, optometrist, dentist, veterinarian, or other hea ...
usually feels a warm or burning sensation.Halaas YP: Medium depth peels. Facial Plas Surg Clin North Am 2004 Aug; 12(3):297-303 Phenol used to be a deep chemical peel. Early phenol peel solutions were very painful and most practitioners would perform it under either
general anesthesia General anaesthesia (UK) or general anesthesia (US) is a medically induced loss of consciousness that renders the patient unarousable even with painful stimuli. This effect is achieved by administering either intravenous or inhalational general ...
, administered by an anesthesiologist or nurse anesthetist. Today it is more correctly referred to as a croton oil peel, since that has proven to be the active ingredient responsible for most of its effects. Recent formulations allow more variation in the depth of treatment, and allow its use under sedation either orally or intravenously, usually in conjunction with local anesthetic injections.


See also

* List of cutaneous conditions


References

{{reflist Skin care