Catuabine
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Catuabines are a group of
tropane alkaloid Tropane alkaloids are a class of bicyclic .2.1alkaloids and secondary metabolites that contain a tropane ring in their chemical structure. Tropane alkaloids occur naturally in many members of the plant family Solanaceae. Certain tropane alkaloid ...
s, isolated from '' Erythroxylum vaccinifolium'', which are used in the preparation of the drug
Catuaba The name Catuaba ( , via Portuguese from Guarani) is used for the infusions of the bark of a number of trees native to Brazil. The most widely used barks are derived from the trees '' Trichilia catigua'' and '' Erythroxylum vaccinifolium''. Othe ...
(which in traditional Brazilian medicine is purported to be an aphrodisiac and central nervous system stimulant, though such claims have not been substantiated). While catuabine A, B and C were isolated and characterized by Graf and Lude (1977, 1978), catuabine D was recently isolated by Zanolari et al. The catuabines are not known to have any physiological effects, this is in contrast to
cocaine Cocaine (from , from , ultimately from Quechua: ''kúka'') is a central nervous system (CNS) stimulant mainly used recreationally for its euphoric effects. It is primarily obtained from the leaves of two Coca species native to South Ameri ...
, which is an active constituent of another species, ''
Erythroxylum coca ''Erythroxylum coca'' is one of two species of cultivated coca. Description The coca plant resembles a blackthorn bush, and grows to a height of . The branches are straight, and the leaves, which have a green tint, are thin, opaque, oval, and tap ...
''.


See also

* Hygrine *
Cuscohygrine Cuscohygrine is a pyrrolidine alkaloid found in coca. It can also be extracted from plants of the family Solanaceae, including ''Atropa belladonna'' (deadly nightshade), ''Datura innoxia'' and ''Datura stramonium'' (jimson weed). Cuscohygrine usua ...


References

* Glasl, S.; Presser, A.; Werner, I.; Haslinger, E.; Jurenitsch, J. (2003): Tropane alkaloids from a Brazilian bark traded as "Catuaba". Scientia Pharmaceutica Vol. 71: 113-119. (,
CODEN CODEN – according to ASTM standard E250 – is a six-character, alphanumeric bibliographic code that provides concise, unique and unambiguous identification of the titles of periodicals and non-serial publications from all subject areas. CODE ...
SCPHA4). * Glasl, S.; Presser, A.; Werner, I.; Haslinger, E.; Jurenitsch, J. (2004): Erratum to Tropane alkaloids from a Brazilian bark traded as "Catuaba". Scientia Pharmaceutica Vol. 72: 97. (,
CODEN CODEN – according to ASTM standard E250 – is a six-character, alphanumeric bibliographic code that provides concise, unique and unambiguous identification of the titles of periodicals and non-serial publications from all subject areas. CODE ...
SCPHA4). * Graf, E.; Lude, W (1977): Alkaloids from Erythroxylum vacciniifolium Martius, 1. pt. Isolation of catuabine A, B and C. ''Archiv der Pharmazie (Weinheim)'' Vol. 310(12): 1005-1010. (,
CODEN CODEN – according to ASTM standard E250 – is a six-character, alphanumeric bibliographic code that provides concise, unique and unambiguous identification of the titles of periodicals and non-serial publications from all subject areas. CODE ...
ARPMAS). * Graf, E.; Lude, W. (1978): Alkaloids from Erythroxylum vacciniifolium Martius, 2. pt. The structures of catuabine A, B and C. ''Archiv der Pharmazie (Weinheim)'' Vol. 311(2): 139-152. (,
CODEN CODEN – according to ASTM standard E250 – is a six-character, alphanumeric bibliographic code that provides concise, unique and unambiguous identification of the titles of periodicals and non-serial publications from all subject areas. CODE ...
ARPMAS). * Zanolari, B.; Wolfeneder, J.L.; Guilet, D.; Marston, A.; Queiroz, E.F.; Paulo, M.Q.; Hostettmann, K. (2003): On-line identification of tropane alkaloids from Erythroxylum vacciniifolium by liquid chromatography-UV detection-multiple mass spectrometry and liquid chromatography-nuclear magnetic resonance spectrometry. ''Journal of Chromatogragraphy'' Vol. 1020A: 75-89. (,
CODEN CODEN – according to ASTM standard E250 – is a six-character, alphanumeric bibliographic code that provides concise, unique and unambiguous identification of the titles of periodicals and non-serial publications from all subject areas. CODE ...
JCRAEY). * Zanolari, B.; Guilet, D.; Marston, A.; Queiroz, E.F.; de Queiroz Paulo, M.; Hostettmann, K. (2003): Tropane alkaloids from the bark of Erythroxylum vacciniifolium. ''Journal of Natural Products'' Vol. 66(4): 497-502. (,
CODEN CODEN – according to ASTM standard E250 – is a six-character, alphanumeric bibliographic code that provides concise, unique and unambiguous identification of the titles of periodicals and non-serial publications from all subject areas. CODE ...
JNPRDF). * Zanolari, B.; Guilet, D.; Marston, A.; Queiroz, E.F.; de Queiroz Paulo, M.; Hostettmann, K. (2005): Methylpyrrole tropane alkaloids from the bark of Erythroxylum vacciniifolium. ''Journal of Natural Products'' Vol. 68(8): 1153-1158. (,
CODEN CODEN – according to ASTM standard E250 – is a six-character, alphanumeric bibliographic code that provides concise, unique and unambiguous identification of the titles of periodicals and non-serial publications from all subject areas. CODE ...
JNPRDF). Tropane alkaloids Alkaloids found in Erythroxylum {{alkaloid-stub