''Cancer: The Emperor of All Maladies'' is a 2015 American

documentary film A documentary film or documentary is a non-fictional film, motion-picture intended to "document reality, primarily for the purposes of instruction, education or maintaining a Recorded history, historical record". Bill Nichols (film critic), Bil ...

produced and directed by Barak Goodman and executive produced by

Ken Burns Kenneth Lauren Burns (born July 29, 1953) is an American filmmaker known for his documentary film, documentary films and television series, many of which chronicle United States, American History of the United States, history and Culture of the ...

. The film, in three episodes of two hours each, is based on the

Pulitzer Prize The Pulitzer Prize () is an award for achievements in newspaper, magazine, online journalism, literature, and musical composition within the United States. It was established in 1917 by provisions in the will of Joseph Pulitzer, who had made h ...

-winning 2010 book '' The Emperor of All Maladies: A Biography of Cancer'', by

Siddhartha Mukherjee Siddhartha Mukherjee (born 21 July 1970) is an Indian-American physician, biologist, and author. He is best known for his 2010 book, '' The Emperor of All Maladies: A Biography of Cancer'', that won notable literary prizes including the 2011 Pu ...

, and describes the history of

cancer Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal b ...

and

cancer treatments Cancer can be treated by surgery, chemotherapy, radiation therapy, hormonal therapy, targeted therapy (including immunotherapy such as monoclonal antibody therapy) and synthetic lethality, most commonly as a series of separate treatments (e.g. ...

, particularly in the

United States The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territorie ...

. The film is narrated by

Edward Herrmann Edward Kirk Herrmann (July 21, 1943 – December 31, 2014) was an American actor, director, and writer. He was perhaps best known for his portrayals of Franklin D. Roosevelt in both the miniseries '' Eleanor and Franklin'' (1976) and 1982 film ...

, who was himself suffering from terminal

brain cancer A brain tumor occurs when abnormal cells form within the brain. There are two main types of tumors: malignant tumors and benign (non-cancerous) tumors. These can be further classified as primary tumors, which start within the brain, and secondar ...

at the time of its production. He died on December 31, 2014, three months before the film's release, making the series his final performance.

Episodes

Participants

The documentary film is narrated by

, and includes the following participants: * Dr. Arnold Levine *

Sherwin Nuland Sherwin may refer to: Surname: *A. N. Sherwin-White (1911–1993), British historian of Ancient Rome *Adam Sherwin, journalist and a former media correspondent for The Times between 1999 and 2010 *Amy Sherwin (1855–1935), the 'Tasmanian Nightinga ...

James P. Allison James Patrick Allison (born August 7, 1948) is an American immunologist and Nobel laureate who holds the position of professor and chair of immunology and executive director of immunotherapy platform at the MD Anderson Cancer Center at the Univ ...

, episode 3 * Dr. Bernard Fisher * Emil J. Freireich * Carl June *

Howard Markel Howard Markel (born April 23, 1960) is an American physician and medical historian. Markel is the George E. Wantz Distinguished Professor of the History of Medicine at the University of Michigan and Director of the University of Michigan's Center ...

* Dr. Donald Pinkel * Dr. Eric Lander * Dr. James Holland *Dr. Jimmie Holland * Dr. Jose Baselga *

Charles Sawyers Charles L. Sawyers (born 1959) is a Howard Hughes Medical Institute (HHMI) investigator who holds the Marie-Josée and Henry R. Kravis Chair of the Human Oncology and Pathogenesis Program (HOPP) at Memorial Sloan Kettering Cancer Center (MSK). HO ...

*Dr. Lori Wilson * Dr. Robert Weinberg * John Bailar * Dr. Siddhartha Mukherjee * Dr. Sidney Farber * Dr. Susan Love *Dr. Suzanne Cole * Dr. Todd Golub * Dr. Vincent DeVita *

Edward R. Murrow Edward Roscoe Murrow (born Egbert Roscoe Murrow; April 25, 1908 – April 27, 1965) was an American broadcast journalist and war correspondent. He first gained prominence during World War II with a series of live radio broadcasts from Europe fo ...

Jerome Groopman Jerome E. Groopman has been a staff writer in medicine and biology for ''The New Yorker'' since 1998. He is also the Dina and Raphael Recanati Chair of Medicine at Harvard Medical School, Chief of Experimental Medicine at Beth Israel Deaconess Me ...

Mary Lasker Mary Woodard Lasker (November 30, 1900February 21, 1994) was an American health activist and philanthropist. She worked to raise funds for medical research and founded the Lasker Foundation. Early life Mary Woodard was born in Watertown, Wisconsi ...

Gallery

Image:Nci-vol-8226-300 bernard fisher.jpg, Dr. Bernard Fisher Image:Dr. Siddhartha Mukherjee 2011.jpg, Dr. Siddhartha Mukherjee Image:Sidney Farber nci-vol-1926-300.jpg, Dr. Sidney Farber Image:Dr. Susan Love.jpg, Dr. Susan Love Image:Mary Lasker.jpg,

Critical response

According to a review in the ''

Los Angeles Times The ''Los Angeles Times'' (abbreviated as ''LA Times'') is a daily newspaper that started publishing in Los Angeles in 1881. Based in the LA-adjacent suburb of El Segundo since 2018, it is the sixth-largest newspaper by circulation in the Un ...

'', the film is "the single most personally relevant documentary of this or any year". According to a review in ''

The New York Times ''The New York Times'' (''the Times'', ''NYT'', or the Gray Lady) is a daily newspaper based in New York City with a worldwide readership reported in 2020 to comprise a declining 840,000 paid print subscribers, and a growing 6 million paid ...

'', the series is "absorbing", is "structured as an ever-evolving medical detective story, but the filmmakers give it heart as well by juxtaposing the history lessons with present-day personal profiles of cancer patients", seems perhaps "too much like a promotional video for cancer researchers and hospitals", and "touches only briefly on the significant issue of costs" but "achieves its main goal, which is to show the human impact of cancer."

References

External links