Canbisol (Nabidrox), is a
synthetic cannabinoid derivative that is the dimethylheptyl
homologue of 9-''nor''-9β-hydroxyhexahydrocannabinol (
HHC). It is a potent
agonist at both the
CB1 and
CB2 receptors
Receptor may refer to:
*Sensory receptor, in physiology, any structure which, on receiving environmental stimuli, produces an informative nerve impulse
*Receptor (biochemistry), in biochemistry, a protein molecule that receives and responds to a n ...
, with a
binding affinity
In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose. The etymology stems from ''ligare'', which means 'to bind'. In protein-ligand binding, the ligand is usually a m ...
of 0.1nM at CB
1 and 0.2nM at CB
2.
It is mainly used in scientific research, in receptor binding studies to determine the structure and function of the
cannabinoid
Cannabinoids () are several structural classes of compounds found in the cannabis plant primarily and most animal organisms (although insects lack such receptors) or as synthetic compounds. The most notable cannabinoid is the phytocannabinoid tet ...
receptors,
but has been made illegal in some countries due to its possible abuse potential as a
cannabinomimetic drug.
The Misuse of Drugs Act 1971 (Amendment) Order 2009
/ref>
See also
* HU-210
HU-210 is a synthetic cannabinoid that was first synthesized in 1988 from (1R,5S)-myrtenol by a group led by Raphael Mechoulam at the Hebrew University. HU-210 is 100 to 800 times more potent than natural THC from cannabis and has an extended d ...
* HU-243
HU-243 (AM-4056) is a synthetic cannabinoid drug that is a single enantiomer of the hydrogenated derivative of the commonly used reference agonist HU-210. It is a methylene homologue of canbisol. It is a potent agonist at both the CB1 and CB ...
* Nabilone
Nabilone, sold under the brand name Cesamet among others, is a synthetic cannabinoid with therapeutic use as an antiemetic and as an adjunct analgesic for neuropathic pain. It mimics tetrahydrocannabinol (THC), the primary psychoactive compound ...
References
Cannabinoids
Benzochromenes
Cyclohexanols
Phenols
{{cannabinoid-stub