CIM-0216 is a chemical compound which acts as a potent and selective activator of the
TRPM3
Transient receptor potential cation channel subfamily M member 3 is a protein that in humans is encoded by the ''TRPM3'' gene.
Function
The product of this gene belongs to the family of transient receptor potential (TRP) channels. TRP channels ...
calcium channel. It produces
nociception
Nociception (also nocioception, from Latin ''nocere'' 'to harm or hurt') is the sensory nervous system's process of encoding noxious stimuli. It deals with a series of events and processes required for an organism to receive a painful stimulus, co ...
and
inflammation
Inflammation (from la, wikt:en:inflammatio#Latin, inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or Irritation, irritants, and is a protective response involving im ...
and is used to study the function of the TRPM3 receptor in these processes.
References
{{Transient receptor potential channel modulators
Oxazoles
Acetamides
Phenyl compounds
Tetrahydroquinolines
Transient receptor potential channel agonists