Bromofluoromethane is a mixed gaseous halomethane soluble in alcohol and very soluble in chloroform. Its

standard molar entropy In chemistry, the standard molar entropy is the entropy content of one mole of pure substance at a standard state of pressure and any temperature of interest. These are often (but not necessarily) chosen to be the standard temperature and pressu ...

, ''S''^o_gas is 276.3 J/(mol K) and

heat capacity Heat capacity or thermal capacity is a physical property of matter, defined as the amount of heat to be supplied to an object to produce a unit change in its temperature. The SI unit of heat capacity is joule per kelvin (J/K). Heat capacity ...

, ''c_p'' is 49.2 J/(mol K).

Preparation

Up to date, it has been prepared by three prevailingly ineffective methods: # From salts of

fluoroacetic acid Fluoroacetic acid is a organofluorine compound with formula CH2FCO2H. It is a colorless solid that is noted for its relatively high toxicity. The conjugate base, fluoroacetate occurs naturally in at least 40 plants in Australia, Brazil, and Afric ...

using a Hunsdiecker type of reaction. # From

dibromofluoromethane Dibromofluoromethane is a mixed halomethane. It is soluble in alcohol, acetone, benzene and chloroform. Applications It can be used to prepare bromofluoromethane by reductive debromination with organotin hydride as tributyltin hydride. Reg ...

by reductive debromination with a Swarts reagent. # From a dihalomethane by an halogen exchange reaction or from a halomethane by catalyzed

bromination In chemistry, halogenation is a chemical reaction that entails the introduction of one or more halogens into a compound. Halide-containing compounds are pervasive, making this type of transformation important, e.g. in the production of polyme ...

fluorination In chemistry, halogenation is a chemical reaction that entails the introduction of one or more halogens into a compound. Halide-containing compounds are pervasive, making this type of transformation important, e.g. in the production of polymers, ...

. The method with the highest yield is reductive debromination of dibromofluoromethane using an organotin hydride.Debrominating dibromofluoromethane with tributyltin hydride
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Uses

Bromofluoromethane is an important reagent in the manufacture of intermediates, pharmaceuticals and other chemicals. Usage of bromofluoromethane is regulated due to its

ozone depletion potential The ozone depletion potential (ODP) of a chemical compound is the relative amount of degradation to the ozone layer it can cause, with trichlorofluoromethane (R-11 or CFC-11) being fixed at an ODP of 1.0. Chlorodifluoromethane (R-22), for exampl ...

(0.73). Its isotopomer CH₂Br¹⁸F contains fluorine-18 (¹⁸F) and is used in radiochemistry.

Supplier

Valliscor
located in Corvallis, Oregon, specializes in bromofluoromethane production generating purities in the 99.9% or greater range.

References

External sources

Determination of the molecular dipole moment of bromofluoromethane
* http://www.valliscor.com/bromofluoromethane {{Halomethanes Halomethanes Organobromides Organofluorides