The Bristol Myers Squibb Company (BMS) is an American multinational

pharmaceutical company The pharmaceutical industry discovers, develops, produces, and markets drugs or pharmaceutical drugs for use as medications to be administered to patients (or self-administered), with the aim to cure them, vaccinate them, or alleviate sympto ...

. Headquartered in

New York City New York, often called New York City or NYC, is the List of United States cities by population, most populous city in the United States. With a 2020 population of 8,804,190 distributed over , New York City is also the L ...

, BMS is one of the world's largest pharmaceutical companies and consistently ranks on the ''Fortune'' 500 list of the largest U.S. corporations. For fiscal 2021, it had a total revenue of $46.4 billion. Bristol Myers Squibb manufactures prescription pharmaceuticals and biologics in several therapeutic areas, including

cancer Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal b ...

HIV/AIDS Human immunodeficiency virus infection and acquired immunodeficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV), a retrovirus. Following initial infection an individual ...

cardiovascular disease Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels. CVD includes coronary artery diseases (CAD) such as angina and myocardial infarction (commonly known as a heart attack). Other CVDs include stroke, h ...

diabetes Diabetes, also known as diabetes mellitus, is a group of metabolic disorders characterized by a high blood sugar level ( hyperglycemia) over a prolonged period of time. Symptoms often include frequent urination, increased thirst and increased ap ...

hepatitis Hepatitis is inflammation of the liver tissue. Some people or animals with hepatitis have no symptoms, whereas others develop yellow discoloration of the skin and whites of the eyes (jaundice), poor appetite, vomiting, tiredness, abdominal pa ...

rheumatoid arthritis Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints. It typically results in warm, swollen, and painful joints. Pain and stiffness often worsen following rest. Most commonly, the wrist and hands are involv ...

, and

psychiatric disorders A mental disorder, also referred to as a mental illness or psychiatric disorder, is a behavioral or mental pattern that causes significant distress or impairment of personal functioning. Such features may be persistent, relapsing and remitti ...

. BMS's primary

research and development Research and development (R&D or R+D), known in Europe as research and technological development (RTD), is the set of innovative activities undertaken by corporations or governments in developing new services or products, and improving existi ...

(R&D) sites are located in Lawrence, New Jersey (formerly Squibb, near

Princeton Princeton University is a private research university in Princeton, New Jersey. Founded in 1746 in Elizabeth as the College of New Jersey, Princeton is the fourth-oldest institution of higher education in the United States and one of the nine ...

Summit, New Jersey Summit is a city in Union County, in the U.S. state of New Jersey. The city is located on a ridge in northern- central New Jersey, within the Raritan Valley and Rahway Valley regions in the New York metropolitan area. At the 2010 United Sta ...

, formerly HQ of

Celgene Celgene Corporation is a pharmaceutical company that makes cancer and immunology drugs. Its major product is Revlimid ( lenalidomide), which is used in the treatment of multiple myeloma, and also in certain anemias. The company is incorporated in ...

New Brunswick, New Jersey New Brunswick is a city (New Jersey), city in and the county seat, seat of government of Middlesex County, New Jersey, Middlesex County, in the U.S. state of New Jersey.Redwood City, California Redwood City is a city on the San Francisco Peninsula in Northern California's Bay Area, approximately south of San Francisco, and northwest of San Jose. Redwood City's history spans its earliest inhabitation by the Ohlone people to being a ...

, and

Seville Seville (; es, Sevilla, ) is the capital and largest city of the Spanish autonomous community of Andalusia and the province of Seville. It is situated on the lower reaches of the River Guadalquivir, in the southwest of the Iberian Peninsula ...

in Spain, with other sites in Devens and

Cambridge, Massachusetts Cambridge ( ) is a city in Middlesex County, Massachusetts, United States. As part of the Boston metropolitan area, the cities population of the 2020 U.S. census was 118,403, making it the fourth most populous city in the state, behind Boston, ...

East Syracuse, New York East Syracuse is an incorporated village and a suburb of the City of Syracuse in eastern Onondaga County, New York, United States. As of the 2010 U.S. census, the village had a population of 3,084. It is located immediately east of Syracuse, in ...

, Braine-l'Alleud, Belgium,

Tokyo, Japan Tokyo (; ja, 東京, , ), officially the Tokyo Metropolis ( ja, 東京都, label=none, ), is the capital and List of cities in Japan, largest city of Japan. Formerly known as Edo, its metropolitan area () is the most populous in the world, ...

Bangalore, India Bangalore (), officially Bengaluru (), is the capital and largest city of the Indian state of Karnataka. It has a population of more than and a metropolitan population of around , making it the third most populous city and fifth most ...

, and Wirral, United Kingdom. BMS previously had an R&D site in

Wallingford, Connecticut Wallingford is a town in New Haven County, Connecticut, United States, centrally located between New Haven and Hartford, and Boston and New York City. The population was 44,396 at the 2020 census. The community was named after Wallingford, in En ...

(formerly Bristol-Myers).

History

Squibb

The Squibb corporation was founded in 1858 by

Edward Robinson Squibb Edward Robinson Squibb (July 4, 1819October 25, 1900) was a medical doctor, a leading American inventor, and manufacturer of pharmaceutics who founded E. R. Squibb and Sons, which eventually became part of the modern pharmaceutical giant Bristol ...

Brooklyn Brooklyn () is a borough of New York City, coextensive with Kings County, in the U.S. state of New York. Kings County is the most populous county in the State of New York, and the second-most densely populated county in the United States, be ...

, New York. Squibb was known as an advocate of quality control and high purity standards early within the pharmaceutical industry. He went on to self-publish an alternative to the U.S. Pharmacopeia titled ''Squibb's Ephemeris of Materia Medica,'' after failing to convince the

American Medical Association The American Medical Association (AMA) is a professional association and lobbying group of physicians and medical students. Founded in 1847, it is headquartered in Chicago, Illinois. Membership was approximately 240,000 in 2016. The AMA's state ...

to incorporate higher purity standards. ''Materia Medica'', Squibb products, and Edward Squibb's opinion on the fundamentals of pharmacy are found in many medical papers of the late 1800s. The ''

American Journal of Pharmacy American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, p ...

'' published more than one hundred papers of Squibb's research surrounding the industry. The sons of Edward Squibb sold the company to Lowell M. Palmer and Theodore Weicker in 1905, who incorporated the company. Around this time, the Squibb logo was developed, which represented the company's products of "uniformity, purity, efficacy, and reliability based on research." Squibb Corporation served as a major supplier of medical goods to the Union Army during the

American Civil War The American Civil War (April 12, 1861 – May 26, 1865; also known by other names) was a civil war in the United States. It was fought between the Union ("the North") and the Confederacy ("the South"), the latter formed by states th ...

, providing portable medical kits containing

morphine Morphine is a strong opiate that is found naturally in opium, a dark brown resin in poppies (''Papaver somniferum''). It is mainly used as a analgesic, pain medication, and is also commonly used recreational drug, recreationally, or to make ...

, surgical anesthetics, and

quinine Quinine is a medication used to treat malaria and babesiosis. This includes the treatment of malaria due to ''Plasmodium falciparum'' that is resistant to chloroquine when artesunate is not available. While sometimes used for nocturnal leg cr ...

for the treatment of malaria (which was endemic in most of the Eastern United States at that time). In 1944, Squibb opened the world's largest penicillin plant in

William McLaren Bristol William McLaren Bristol (28July 18601935) was one of the two co-founders of Bristol-Myers, now part of Bristol-Myers Squibb. Myers and Bristol founded the company that would evolve into an international pharmaceutical giant in Bristol's birthplac ...

and

John Ripley Myers John Ripley Myers (October 8, 1864 – December 22, 1899) was a co-founder (along with William McLaren Bristol) of the pharmaceutical company Bristol-Myers. Life John Ripley Myers was born in Cleveland, Ohio, on October 8, 1864. His father was ...

purchased the Clinton Pharmaceutical company of

Clinton Clinton is an English toponymic surname, indicating one's ancestors came from English places called Glympton or Glinton.Hanks, P. & Hodges, F. ''A Dictionary of Surnames''. Oxford University Press, 1988 Clinton has frequently been used as a given ...

, New York. In May 1898, they decided to rename it Bristol, Myers and Company. Following Myers' death in 1899, Bristol changed the name to the Bristol-Myers Corporation. During the 1890s, the company introduced its first nationally recognized product

Sal Hepatica Sal Hepatica is the name of a mineral salt laxative that was produced and marketed by Bristol-Myers from its inception in 1887, becoming its first nationally recognized product in 1903, until 1958. When dissolved in water, it was said to reproduce ...

, a laxative mineral salt, followed by Ipana toothpaste in 1901.Bert Rosenbloom, ''Marketing Channels''
Bristol-Myers Squibb
, 2011, page 609 Other divisions were Clairol (hair colors and haircare) and Drackett (household products such as

Windex Windex is an American brand of glass and hard-surface cleaner that was invented by the Drackett Company in 1933 and has been marketed throughout the intervening decades—originally in glass containers, later in plastic ones. Drackett sold the W ...

and

Drano Drano (styled as Drāno) is an American brand of chemical drain cleaner that is manufactured by S. C. Johnson & Son. Crystal Drano According to the National Institutes of Health's Household Products Database, the crystal form is composed of: * ...

). In 1943, Bristol-Myers acquired Cheplin Biological Laboratories, a producer of acidophilus milk in

, and converted the plant to produce

penicillin Penicillins (P, PCN or PEN) are a group of β-lactam antibiotics originally obtained from ''Penicillium'' moulds, principally '' P. chrysogenum'' and '' P. rubens''. Most penicillins in clinical use are synthesised by P. chrysogenum using ...

for the World War II Allied forces. After the war, the company renamed the plant

Bristol Laboratories The Bristol Myers Squibb Company (BMS) is an American multinational pharmaceutical company. Headquartered in New York City, BMS is one of the world's largest pharmaceutical companies and consistently ranks on the ''Fortune'' 500 list of the lar ...

in 1945 and entered the civilian

antibiotics An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention o ...

market, where it faced competition from Squibb. Penicillin production at the East Syracuse plant ended in 2005, when it became less expensive to produce overseas. As of 2010, the facility was used for the manufacturing process development and production of other biologic medicines for clinical trials and commercial use.

Merger

In 1989, Bristol-Myers and Squibb merged and became Bristol-Myers Squibb. In 1999, then-U.S. President Bill Clinton awarded Bristol-Myers Squibb the National Medal of Technology, the nation's highest recognition for technological achievement, "for extending, and enhancing human life through innovative pharmaceutical research and development and for redefining the science of clinical study through groundbreaking and hugely complex clinical trials that are recognized models in the industry."

2000 to 2010

In 2002, the company was involved in a lawsuit of illegally maintaining a monopoly on Taxol, its cancer treatment, and it was again sued for the antitrust lawsuit 5 years later, which cost the company $125 million for settlement. Also in 2002, Bristol-Myers Squibb was involved in an

accounting scandal Accounting, also known as accountancy, is the measurement, processing, and communication of financial and non financial information about economic entities such as businesses and corporations. Accounting, which has been called the "language ...

that resulted in a significant restatement of revenues from 1999 to 2001. The restatement was the result of an improper booking of sales related to "

channel stuffing Channel stuffing is a business practice in which a company, or a sales force within a company, inflates its sales figures by forcing more products through a distribution channel than the channel is capable of selling. Also known as trade loading, ...

" as the practice of offering excess inventory to customers to create higher sales numbers. The company has since settled with the

United States Department of Justice The United States Department of Justice (DOJ), also known as the Justice Department, is a federal executive department of the United States government tasked with the enforcement of federal law and administration of justice in the United State ...

and

Securities and Exchange Commission The U.S. Securities and Exchange Commission (SEC) is an independent agency of the United States federal government, created in the aftermath of the Wall Street Crash of 1929. The primary purpose of the SEC is to enforce the law against market ...

, agreeing to pay $150 million, while neither admitting nor denying guilt. On October 24, 2002, Bristol-Myers Squibb Co. restated earnings downward for parts of 2000 and 2001, while revising this year's earnings upward because of its massive inventory backlog imbroglio that spurred two government investigations. On March 15, 2004, Bristol-Myers Squibb Co. adjusted upward its fourth-quarter and full-year 2003 results after reversing an earlier decision about how to deal with accounting errors made in prior years. As part of a deferred prosecution agreement, the company was placed under the oversight of a monitor appointed by the U.S. attorney in w Jersey. In addition, the former head of the Pharma group, Richard Lane, and the ex-CFO, Fred Schiff, were indicted for federal securities violations. In July 2006, an investigation of the company was made public, and the

FBI The Federal Bureau of Investigation (FBI) is the domestic Intelligence agency, intelligence and Security agency, security service of the United States and its principal Federal law enforcement in the United States, federal law enforcement age ...

raided the company's corporate offices. The investigation centered on the distribution of Plavix and charges of collusion. On September 12, 2006, the monitor, former Federal Judge Frederick B. Lacey, urged the company to remove then-CEO Peter Dolan over the Plavix dispute. Later that day, BMS announced that Dolan would indeed step down. The deferred prosecution agreement expired in June 2007 and the Department of Justice did not take any further legal action against the company for matters covered by the DPA. Under CEO Jim Cornelius, who was CEO following Dolan until May 2010, all executives involved in the "channel-stuffing" and generic competition scandals have since left the company. In 2009, the company began a major restructuring focusing on the pharmaceutical business and biologic products, along with productivity initiatives and cost-cutting and streamlining business operations through a multiyear program of on-going layoffs. This was part of a business strategy launched in 2007 to transform the company from a large, diversified pharmaceutical company to a specialty biopharma company, which also included the closure of half of their manufacturing facilities. As another cost-cutting measure, Bristol-Myers Squibb also reduced health-care subsidies for retirees and plans to freeze their pension plan at the end of 2009. BMS is a ''Fortune'' 500 Company (#114 in 2010 list). ''Newsweek's ''2009 Green Ranking recognized Bristol-Myers Squibb as eighth among 500 of the largest United States corporations. Also, BMS was included in the 2009 Dow Jones Sustainability North America Index of leading sustainability-driven companies.

Lamberto Andreotti Lamberto Andreotti (born 6 July 1950) is an Italian businessman. He is currently executive chairman of the board of Bristol Myers Squibb. Biography Early life Andreotti was born in Rome, Italy, in 1950, the son of Italian Senator and Presiden ...

was named

CEO A chief executive officer (CEO), also known as a central executive officer (CEO), chief administrator officer (CAO) or just chief executive (CE), is one of a number of corporate executives charged with the management of an organization especially ...

in 2010; he had previously served as "president and

COO COO or coo may refer to: Business * Certificate of origin, used in international trade * Chief operating officer or chief operations officer, high-ranking corporate official * Concept of operations, used in Systems Engineering Management Process ...

responsible for all pharmaceutical operations worldwide."

2010 onward

Bristol Myers Squibb, Moreton, Wirral - IMG 0369

In 2010, Lou Schmukler joined Bristol-Myers Squibb as the president of global product development and design. Schmukler led the team that completed the company's strategic transformation to a specialty biopharmaceutical company that had begun in 2007. As of 2011, the company had a dozen manufacturing facilities and six product development sites. Citing major developments and a market capitalization of US$87 billion and stock appreciation of 61.4%, Bristol-Myers Squibb was ranked as the best drug company of 2013 by ''Forbes'' magazine. In December 2014, the company received FDA approval for the use of the PD-1 inhibitor nivolumab (Opdivo) in treating patients whose skin cancer cannot be removed or have not responded to previous drug therapies. In February 2015, the company initiated a research partnership with Rigel Pharmaceuticals which could generate more than $339 million. In March, the company obtained an exclusive opportunity to both licence and commercialise PROSTVAC,

Bavarian Nordic Bavarian Nordic A/S is a fully integrated biotechnology company focused on the development, manufacturing and commercialization of vaccines for infectious diseases and cancer immunotherapies. The company is headquartered in Hellerup, Denmark, wit ...

's phase III prostate-specific antigen targeting cancer immunotherapy. Bavarian Nordic would receive an upfront payment of $60 million and incremental payments up to $230 million, if the overall survival of test patients exceeds that seen in Phase II tests. Bavarian could also receive milestone payments of between $110 million and $495 million, dependent on regulatory authorization, and these payments have the potential to total up to $975 million. In May 2015, Dr. Giovanni Caforio became CEO of the company; Caforio was formerly the company's

and succeeded Andreotti upon his retirement. Andreotti subsequently succeeded James Cornelius as

executive chairman The chairperson, also chairman, chairwoman or chair, is the presiding officer of an organized group such as a board, committee, or deliberative assembly. The person holding the office, who is typically elected or appointed by members of the grou ...

upon his retirement. In late February 2017, ''

The Wall Street Journal ''The Wall Street Journal'' is an American business-focused, international daily newspaper based in New York City, with international editions also available in Chinese and Japanese. The ''Journal'', along with its Asian editions, is published ...

'' and ''

Fortune Fortune may refer to: General * Fortuna or Fortune, the Roman goddess of luck * Luck * Wealth * Fortune, a prediction made in fortune-telling * Fortune, in a fortune cookie Arts and entertainment Film and television * ''The Fortune'' (1931 film) ...

'', among others, reported that activist investor Carl Icahn had taken a stake in the company, signaling a potential future takeover from the likes of Gilead Sciences. In April 2018, the company reported net income of $1.5 billion, or 91 cents per share, for the first quarter of the year, thanks to the increased sales of their cancer drug Opdivo.

Corporate acquisitions and divestments as Bristol Myers Squibb

In August 2009, during a major restructuring activity, BMS acquired the

biotechnology Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used b ...

firm

Medarex Medarex (former NASDAQ symbol: MEDX ) was an American biopharmaceutical company based in Princeton, New Jersey, with manufacturing facilities in Bloomsbury and Annandale, New Jersey, and research facilities in Milpitas and Sunnyvale, California. ...

as part of the company's "String of Pearls" strategy of alliances, partnerships, and acquisitions. In November 2009, Bristol Myers Squibb announced that it was "splitting off" Mead Johnson Nutrition by offering BMY shareholders the opportunity to exchange their stock for shares in Mead Johnson. According to Bristol Myers Squibb, this move was expected to further sharpen the company's focus on biopharmaceuticals. In October 2010, the company acquired ZymoGenetics, securing an existing product, as well as pipeline assets in hepatitis C, cancer, and other therapeutic areas. Bristol Myers Squibb agreed to pay around $2.5 billion in cash to buy Inhibitex Inc. in attempt to compete with

Gilead Gilead or Gilad (; he, גִּלְעָד ''Gīləʿāḏ'', ar, جلعاد, Ǧalʻād, Jalaad) is the ancient, historic, biblical name of the mountainous northern part of the region of Transjordan.''Easton's Bible Dictionary'Galeed''/ref> Th ...

Pharmasset Pharmasset Inc. was a pharmaceutical company based in Princeton, New Jersey in the United States. The company develops antiviral drugs for HIV (including racivir), hepatitis B (including clevudine, marketed as Levovir), and hepatitis C. In N ...

to produce

hepatitis C Hepatitis C is an infectious disease caused by the hepatitis C virus (HCV) that primarily affects the liver; it is a type of viral hepatitis. During the initial infection people often have mild or no symptoms. Occasionally a fever, dark urine, a ...

drugs. The settlement will be finished in 2 months for its Inhibitex's shareholders acceptance of 126% premium price of its price over the previous 20 trading days ended on January 6. On June 29, BMS extended its portfolio of

treatments when it agreed to buy

Amylin Pharmaceuticals Amylin Pharmaceuticals is a biopharmaceutical company based in San Diego, CA, that was founded in 1987. The company was engaged in the discovery, development and commercialization of drug candidates for the treatment of diabetes, obesity and othe ...

for around in cash and pay to Eli Lilly to cover Amylin's debt and its outstanding collaboration-related obligations. AstraZeneca, which already collaborated on several diabetes treatments with BMS, agreed to pay US$3.4 billion in cash for the right to continue development of Amylin's products. Two years later, the company divested Amylin to AstraZeneca. In April 2014, BMS announced its acquisition of iPierian for up to $725 million. In February 2015, the company acquired Flexus Biosciences for $1.25 billion. As part of this deal, BMS will gain full rights to Flexus' lead small molecule IDO1-inhibitor, F001287. In November, the company acquired the

drug developer Cardioxyl for up to $2.075 billion. The deal strengthens the BMS' critical pipelines with the phase II candidate for

acute decompensated heart failure Acute decompensated heart failure (ADHF) is a sudden worsening of the signs and symptoms of heart failure, which typically includes difficulty breathing (dyspnea), edema, leg or feet swelling, and Fatigue (medical), fatigue. ADHF is a common and ...

CXL-1427 Cimlanod (development codes CXL-1427 and BMS-986231) is an experimental drug for the treatment of acute decompensated heart failure. It was discovered by Cardioxyl Pharmaceuticals, which was acquired by Bristol-Myers Squibb. It is a nitroxyl don ...

. In March 2016, the company announced it would acquire Padlock Therapeutics for up to $600 million. In early July, the company announced it would acquire Cormorant Pharmaceuticals for $520 million, boosting BMS' oncology offering through Cormorants monoclonal antibody targeted against interleukin-8. In August 2017 the company acquired IFM Therapeutics for $300 million upfront, with contingency payments of $1.01 billion due on certain milestones – allowing BMS to better compete against

Merck & Co Merck & Co., Inc. is an American multinational pharmaceutical company headquartered in Rahway, New Jersey, and is named for Merck Group, founded in Germany in 1668, of whom it was once the American arm. The company does business as Merck Sharp ...

's cancer rival treatment, Keytruda. In early January 2019, the company announced it would acquire

(NASDAQ:CELG) for $74 billion ($95 billion including debt), in a deal that would become the largest pharmaceutical-company acquisition ever. The Celgene acquisition aimed to be a refresher to the company's pipeline, helping to overcome from declining sales of

Opdivo Nivolumab, sold under the brand name Opdivo, is a medication used to treat a number of types of cancer. This includes melanoma, lung cancer, malignant pleural mesothelioma, renal cell carcinoma, Hodgkin lymphoma, head and neck cancer, urothel ...

relative to competitor Keytruda. Under the terms of the deal, Celgene shareholders would receive one BMS share as well as $50 in cash for each Celgene share held, valuing Celgene at $102.43 a share; representing a 54% premium to the previous days closing price. Investor opposition to this acquisition, leading into an April 12 shareholder vote, appeared when BMS's second-largest investor,

Wellington Management Wellington Management Company is a private, independent investment management firm with client assets under management totaling over US$1 trillion based in Boston, Massachusetts, United States. The firm serves as an investment advisor to over 2 ...

, voiced its opposition, followed by investor Starboard Value. In April 2019 BMS announced that 75% of its shareholders voted to approve the pending merger with Celgene. Transaction to close in the third quarter of 2019, subject to regulatory approvals. Newly issued BMS shares and CVRs will commence trading on the New York Stock Exchange, with the CVRs trading under the symbol 'BMYRT'. The strategic divestment of the company's consumer health business, UPSA, to Taisho completed in 2019. UPSA focused product delivery on France and the rest of Europe. As early as 2005, the company had divested individual consumer products, and its US- and Canada-focused consumer products business. In August, the Amgen announced it would acquire the

Otezla Apremilast, sold under the brand name Otezla among others, is a medication for the treatment of certain types of psoriasis and psoriatic arthritis. It may also be useful for other immune system-related inflammatory diseases. The drug acts as a se ...

drug programme from

for $13.4 billion, as part of Celgene and BMS's merger deal. In February 2020, BMS and partner Biomotiv launched a new company called Anteros Pharmaceuticals, which focuses on creating inflammation and fibrosis medicines. In August, the business announced it would acquire Forbius and its TGF-beta 1 &

TGF-beta 3 Transforming growth factor beta (TGF-β) is a multifunctional cytokine belonging to the transforming growth factor superfamily that includes three different mammalian isoforms (TGF-β 1 to 3, HGNC symbols TGFB1, TGFB2, TGFB3) and many other sign ...

inhibitors. In October, BMS announced it would acquire cardiology company MyoKardia for $13.1 billion ($225 per share) gaining control of mavacamten, a cardiovascular drug for obstructive hypertrophic cardiomyopathy (HCM), and the development of two key treatments: danicamtiv (MYK-491) and MYK-224. In June 2022, BMS announced it would acquire Turning Point Therapeutics Inc for $4.1 billion in cash ($76 per share, a 122.5% premium to its last closing price), helping to boost its compliment of cancer drugs, specifically repotrectinib.

List of mergers and acquisitions

The following is an illustration of the company's major mergers and acquisitions and historical predecessors: *Bristol-Myers Squibb (Formed by the merger of Squibb Corporation (Est 1858) and Bristol-Myers (Est 1887)) **

Adnexus Therapeutics In anatomy, adnexa (plural) refers to the appendages of an organ. The term ''adnexa'' is from the Latin word ''adnexa'' (appendages). More specifically, it can refer to: * Adnexa of eye (accessory visual structures) * Adnexa of skin (skin appenda ...

** ConvaTec ** Kosan Biosciences **

(Acq 2009) ** ZymoGenetics (Acq 2010) **

Amira Pharmaceuticals Amira, Ameerah, or Ameera may refer to: Arts and entertainment * ''Amira'' (album), by Amira Willighagen, 2014 * ''Amira'' (film), a 2021 Jordanian film People * Amira (name), an Arabic and Hebrew female given name * Amira (singer), American sin ...

** Inhibitex Inc (Acq 2012) **

(Acq 2012 jointly with AstraZeneca) ** iPierian (Acq 2014) **

Flexus Biosciences (English: Travelcard; formerly named Flexus) is an electronic ticket system that was introduced on all public transport in Greater Oslo, in 2009 using Thales technology. The system may eventually replace all paper tickets on trips with Ruter ( ...

(Acq 2015) ** Cardioxyl (Acq 2015) ** Padlock Therapeutics (Acq 2016) ** Cormorant Pharmaceuticals (Acq 2016) ** IFM Therapeutics (Acq 2017) **

(Acq 2019) *** Signal Pharmaceuticals, Inc (Acq 2000) *** Anthrogenesis (Acq 2002) *** Pharmion Corporation (Acq 2008) *** Gloucester Pharmaceuticals (Acq 2009) *** Abraxis BioScience Inc (Acq 2010) *** Avila Therapeutics, Inc (Acq 2012) *** Quanticel (Acq 2015) *** Receptos (Acq 2015) *** EngMab AG (Acq 2016) *** Delinia (Acq 2017) *** Impact Biomedicines (Acq 2018) ***

Juno Therapeutics Juno Therapeutics Inc is an American biopharmaceutical company founded in 2013 through a collaboration of the Fred Hutchinson Cancer Research Center, Memorial Sloan-Kettering Cancer Center and pediatrics partner Seattle Children's Research Instit ...

(Acq 2018) **** AbVitro (Acq 2016) **** RedoxTherapies (Acq 2016) ** Forbius (Acq 2020) ** MyoKardia (Acq 2020) ** Turning Point Therapeutics (Acq 2022)

Finances

For the fiscal year 2018,Bristol Myers Squibb reported earnings of US$1.007 billion, with an annual revenue of US$20.776 billion, an increase of 6.9% over the previous fiscal cycle. Bristol-Myers Squibb's shares traded at over $55 per share, and its market capitalization was valued at over US$81.6 billion in October 2018. In 2018, 85% of the company's revenues came from just five products. In 2018, Bristol-Myers Squibb spent 36% of its total revenue on R&D expenses. Bristol-Myers Squibb ranked 145th on the

Fortune 500 The ''Fortune'' 500 is an annual list compiled and published by ''Fortune'' magazine that ranks 500 of the largest United States corporations by total revenue for their respective fiscal years. The list includes publicly held companies, along ...

list of the largest United States corporations by revenue in 2018.

Carbon footprint

Bristol Myers Squibb reported Total CO2e emissions (Direct + Indirect) for the twelve months ending 31 December 2020 at 278 Kt (-6 /-2.1% y-o-y).Alt URL
/ref> The company aims to become net neutral carbon by 2040.

Pharmaceuticals

The following is a list of key pharmaceutical products: ''Cardiovascular diseases'' *Avalide ( irbesartan/ hydrochlorothiazide) – comarketed with Sanofi *Avapro ( irbesartan) – comarketed with Sanofi *Coumadin (

warfarin Warfarin, sold under the brand name Coumadin among others, is a medication that is used as an anticoagulant (blood thinner). It is commonly used to prevent blood clots such as deep vein thrombosis and pulmonary embolism, and to prevent strok ...

) *Eliquis (

apixaban Apixaban, sold under the brand name Eliquis, is an anticoagulant medication used to treat and prevent blood clots and to prevent stroke in people with nonvalvular atrial fibrillation through directly inhibiting factor Xa. Specifically it is u ...

) – comarketed with

Pfizer Pfizer Inc. ( ) is an American multinational pharmaceutical and biotechnology corporation headquartered on 42nd Street in Manhattan, New York City. The company was established in 1849 in New York by two German entrepreneurs, Charles Pfizer ...

*Plavix (

clopidogrel Clopidogrel — sold under the brand name Plavix, among others — is an antiplatelet medication used to reduce the risk of heart disease and stroke in those at high risk. It is also used together with aspirin in heart attacks and following t ...

) – comarketed with Sanofi *Pravachol ( pravastatin) ''Diabetes mellitus'' *Bydureon ( exenatide extended-release) – marketed by BMS only in some countries *Byetta ( exenatide) – marketed by BMS only in some countries, such as

Russian Federation Russia (, , ), or the Russian Federation, is a List of transcontinental countries, transcontinental country spanning Eastern Europe and North Asia, Northern Asia. It is the List of countries and dependencies by area, largest country in the ...

*Farxiga/Forxiga ( dapagliflozin) *Glucophage ( metformin) – marketed by BMS only in USA *Glucophage XR ( metformin extended release) – marketed by BMS only in USA *Glucovance ( Glyburide/metformin) – marketed by BMS only in USA *Kombiglyze XR/Komboglyze ( saxagliptin/ metformin extended release) – comarketed with AstraZeneca *Onglyza ( saxagliptin) – comarketed with AstraZeneca ''Infectious diseases, including HIV infection and associated conditions'' *

Atripla Efavirenz/emtricitabine/tenofovir, sold under the brand name Atripla among others, is a fixed-dose combination antiretroviral medication used to treat HIV/AIDS. It contains efavirenz, emtricitabine, and tenofovir disoproxil. It can be used by ...

(

efavirenz Efavirenz (EFV), sold under the brand names Sustiva among others, is an antiretroviral medication used to treat and prevent HIV/AIDS. It is generally recommended for use with other antiretrovirals. It may be used for prevention after a needlest ...

/ emtricitabine/

tenofovir disoproxil fumarate Tenofovir disoproxil, sold under the trade name Viread among others, is a medication used to treat chronic hepatitis B and to prevent and treat HIV/AIDS. It is generally recommended for use with other antiretrovirals. It may be used for preven ...

) – comarketed with Gilead Sciences *Azactam (

aztreonam Aztreonam, sold under the brand name Azactam among others, is an antibiotic used primarily to treat infections caused by gram-negative bacteria such as ''Pseudomonas aeruginosa''. This may include bone infections, endometritis, intra abdominal ...

) *Baraclude ( entecavir) *Daklinza ( daclatasvir) *Evotaz (

atazanavir/cobicistat Atazanavir/cobicistat, sold under the brand name Evotaz, is a fixed-dose combination antiretroviral medication used to treat and prevent HIV/AIDS. It contains atazanavir and cobicistat. Atazanavir is an HIV protease inhibitor and cobicistat is an ...

) *Megace ( megestrol acetate) *Reyataz ( atazanavir) *Sustiva/Stocrin (

) *Videx ( didanosine) *Videx EC ( didanosine delayed-release) *Zerit ( stavudine) ''Inflammatory disorders'' *Kenalog-10 (

triamcinolone acetonide Triamcinolone acetonide, sold under the brand name Kenalog among others, is a synthetic corticosteroid medication used topically to treat various skin conditions, to relieve the discomfort of mouth sores, and by injection into joints to treat ...

) *Kenalog-40 (triamcinolone acetonide) ''Oncology'' *Abecma ( idecabtagene vicleucel) *BiCNU (

carmustine Carmustine, sold under the brand name BiCNU among others, is a medication used mainly for chemotherapy. It is a nitrogen mustard β-chloro- nitrosourea compound used as an alkylating agent. Description Carmustine is an orange-yellow solid medica ...

) *Breyanzi (

lisocabtagene maraleucel Lisocabtagene maraleucel, sold under the brand name Breyanzi, is a cell-based gene therapy used to treat large B-cell lymphoma. Side effects include hypersensitivity reactions, serious infections, low blood cell counts, and a weakened immune sy ...

) *CeeNU (

lomustine Lomustine (INN); abbreviated as CCNU; original brand name CeeNU, now marketed as Gleostine) is an alkylating nitrosourea compound used in chemotherapy. It is closely related to semustine and is in the same family as streptozotocin. It is a highly ...

) *Droxia/Hydrea (

hydroxycarbamide Hydroxycarbamide, also known as hydroxyurea, is a medication used in sickle-cell disease, essential thrombocythemia, chronic myelogenous leukemia, polycythemia vera, and cervical cancer. In sickle-cell disease it increases fetal hemoglobin and d ...

) *Empliciti ( Elotuzumab) *Erbitux (

cetuximab Cetuximab, sold under the brand name Erbitux, is an epidermal growth factor receptor (EGFR) inhibitor medication used for the treatment of metastatic colorectal cancer and head and neck cancer. Cetuximab is a chimeric (mouse/human) monoclonal an ...

) *Etopophos ( etoposide) *Ixempra (

ixabepilone Ixabepilone (INN; also known as azaepothilone B, codenamed BMS-247550) is a pharmaceutical drug developed by Bristol-Myers Squibb as a chemotherapeutic medication for cancer. History Ixabepilone is a semi-synthetic analog of epothilone B, a natura ...

) *Lysodren (

mitotane Mitotane, sold under the brand name Lysodren, is a steroidogenesis inhibitor and cytostatic antineoplastic medication which is used in the treatment of adrenocortical carcinoma and Cushing's syndrome. It is a derivative of the early insecticide ...

) *Megace ( megestrol acetate) *Opdivo ( nivolumab) is a programmed death receptor blocking antibody used for the treatment of unresectable or metastatic melanoma and metastatic squamous non-small-cell lung carcinoma. In contrast to traditional chemotherapies and targeted anti-cancer therapies, which exert their effects by direct cytotoxic or tumor growth inhibition, nivolumab acts by inducing the immune system to attack the tumor. *Sprycel ( dasatinib) *Taxol (

paclitaxel Paclitaxel (PTX), sold under the brand name Taxol among others, is a chemotherapy medication used to treat a number of types of cancer. This includes ovarian cancer, esophageal cancer, breast cancer, lung cancer, Kaposi's sarcoma, cervical cancer ...

). At one time, BMS held the solitary contract to harvest the bark of endangered

yew Yew is a common name given to various species of trees. It is most prominently given to any of various coniferous trees and shrubs in the genus ''Taxus'': * European yew or common yew (''Taxus baccata'') * Pacific yew or western yew (''Taxus br ...

trees on United States territory for the manufacture of

chemotherapy Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents or alkylating agents) as part of a standardized chemotherapy regimen. Chemotherap ...

drug

(Taxol). Current paclitaxel production comes from renewable sources. BMS also held the original paclitaxel license, but there are now multiple generic producers. *Vumon (

teniposide Teniposide (trade name Vumon) is a chemotherapeutic medication used in the treatment of childhood acute lymphocytic leukemia (ALL), Hodgkin's lymphoma, certain brain tumours, and other types of cancer. It is in a class of drugs known as podophyllot ...

) *Yervoy (

ipilimumab Ipilimumab, sold under the brand name Yervoy, is a monoclonal antibody medication that works to activate the immune system by targeting CTLA-4, a protein receptor that downregulates the immune system. Cytotoxic T lymphocytes (CTLs) can recognize ...

) ''Psychiatry'' *Abilify ( aripiprazole comarketed with Otsuka Pharmaceutical) ''Rheumatic disorders'' *Orencia (

abatacept Abatacept, sold under the brand name Orencia, is a medication used to treat autoimmune diseases like rheumatoid arthritis, by interfering with the immune activity of T cells. It is a modified antibody. Abatacept is a fusion protein composed of ...

) ''Transplant rejection'' *Nulojix ( belatacept)

Out of production

* Ipana

Divested brands

(Former Bristol-Myers brands, now divested) *

Bufferin Aspirin, also known as acetylsalicylic acid (ASA), is a nonsteroidal anti-inflammatory drug (NSAID) used to reduce pain, fever, and/or inflammation, and as an antithrombotic. Specific inflammatory conditions which aspirin is used to treat inc ...

Excedrin Aspirin(acetylsalicylic acid) / paracetamol(acetaminophen) / caffeine is a combination drug for the treatment of pain, especially tension headache and migraine. It is sold in the US under the trade names Goody's Powder and Excedrin, although no ...

* Ban Deodorant *Vitalis (hair tonic) *Ammens (medicated powder) *Final Net (hair spray) *Comtrex (cold relief capsules) * Keri (lotion)

Products under development

The following is a selective list of investigational products under development, as of 2015: * Beclabuvir (BMS-791325) – phase III *

BMS-906024 BMS-906024 is a drug with a benzodiazepine structure, developed by Bristol-Myers Squibb and disclosed at the spring 2013 American Chemical Society The American Chemical Society (ACS) is a scientific society based in the United States that s ...

– phase I *

BMS-955176 BMS-955176 is an experimental second generation HIV maturation inhibitor under development by Bristol-Myers Squibb for use in the treatment of HIV infection. By blocking the maturation of the virus, it prevents viral reproduction in host CD4+ T ...

– phase II *

Brivanib alaninate Brivanib alaninate (INN/USAN) also known as BMS-582664 is an investigational, anti-tumorigenic drug for oral administration. The drug is being developed by Bristol-Myers Squibb for the treatment of hepatocellular carcinoma or HCC (also called '' ...

(BMS-582664) – development terminated * Elotuzumab (BMS-901608) – phase III * Fostemsavir (BMS-663068) – approved in the United States in July 2020 *

Lirilumab Lirilumab (INN) is a human monoclonal antibody designed for the treatment of cancer. It binds to KIR2DL1/2L3. This drug was developed by Innate Pharma and is licensed to Bristol-Myers Squibb. Clinical trials A phase 2 clinical trial for acute m ...

(BMS-986015) *

Lulizumab pegol Lulizumab pegol (INN; development code BMS-931699) is a monoclonal antibody designed for the treatment of autoimmune diseases.

(BMS-931699) – phase II

Public-private engagement

Bristol-Myers Squibb engages with the public and private sectors in a variety of settings including to promote

, academic funding, event sponsorship,

philanthropy Philanthropy is a form of altruism that consists of "private initiatives, for the Public good (economics), public good, focusing on quality of life". Philanthropy contrasts with business initiatives, which are private initiatives for private goo ...

, and political lobbying.

Academia and education

Institute for Advanced Study The Institute for Advanced Study (IAS), located in Princeton, New Jersey, in the United States, is an independent center for theoretical research and intellectual inquiry. It has served as the academic home of internationally preeminent scholar ...

- Gift matching and direct donor. * Mentoring in IBD - Sponsor. *

Northern Ontario School of Medicine Northern Ontario School of Medicine University (NOSM University; french: Université de l'École de médecine du Nord de l'Ontario) is a public medical university in the Canadian province of Ontario. It is mandated both to educate doctors and t ...

(NOSM) - Donor. * Population Health Research Institute (PHRI) at

McMaster University Medical School The Michael G. DeGroote School of Medicine, known as the McMaster University School of Medicine prior to 2004, is the medical school of McMaster University in Hamilton, Ontario, Canada. It is operated by the McMaster Faculty of Health Sciences. It ...

- Partner. *

University of Toronto The University of Toronto (UToronto or U of T) is a public research university in Toronto, Ontario, Canada, located on the grounds that surround Queen's Park. It was founded by royal charter in 1827 as King's College, the first institution ...

- Donor. *

University of Washington The University of Washington (UW, simply Washington, or informally U-Dub) is a public research university in Seattle, Washington. Founded in 1861, Washington is one of the oldest universities on the West Coast; it was established in Seattle a ...

- Donor.

Conferences and events

* Women in Medicine Summit - Sponsor. * World Neuroscience Innovation Forum - Sponsor.

Healthcare

Centre for Addiction and Mental Health The Centre for Addiction and Mental Health (CAMH, pronounced , french: Centre de toxicomanie et de santé mentale) is a psychiatric teaching hospital located in Toronto and ten community locations throughout the province of Ontario, Canada. It re ...

(CAMH) - Donor. *

Princess Margaret Cancer Centre The Princess Margaret Cancer Centre (previously, ''Princess Margaret Hospital'') is a scientific research centre and a teaching hospital in Toronto, Ontario, Canada, affiliated with the University of Toronto Faculty of Medicine as part of the Univ ...

(PMCC) - Foundation donor and sponsor for the PMCC Conference. *

Scarborough Health Network Scarborough Health Network (SHN) is a hospital network in Scarborough, Toronto, Ontario, Canada. It operates the Scarborough General, Centenary, and Birchmount hospitals. The three are major community health hospitals with teaching affiliations t ...

(SHN) - Donor to the Scarborough Health Foundation. *

SickKids The Hospital for Sick Children (HSC), corporately branded as SickKids, is a major pediatric teaching hospital located on University Avenue in Toronto, Ontario, Canada. Affiliated with the Faculty of Medicine of the University of Toronto, the hospi ...

- Donor to the SickKids Foundation. *

Sinai Health System The Sinai Health is a hospital system which serves Toronto, Ontario, Canada. It comprises two hospitals, Mount Sinai Hospital (Toronto), Mount Sinai Hospital (an acute care hospital) and Hennick Bridgepoint Hospital, formally Bridgepoint Active H ...

- Donor to the Sinai Health Foundation. *

Sunnybrook Health Sciences Centre Sunnybrook Health Sciences Centre (SHSC), commonly known as Sunnybrook Hospital or simply Sunnybrook, is an academic health science centre An academic medical centre (AMC), variously also known as academic health science centre, academic healt ...

- Donor.

Media

National Geographic Society The National Geographic Society (NGS), headquartered in Washington, D.C., United States, is one of the largest non-profit scientific and educational organizations in the world. Founded in 1888, its interests include geography, archaeology, and ...

- Donor. *

National Press Foundation The National Press Foundation is a nonprofit journalism training organization. It educates journalists on complex issues and trains them in reporting tools and techniques. It recognizes and encourages excellence in journalism through its awards. ...

- Funder.

Medical societies

American Society of Hematology The American Society of Hematology (ASH) is a professional organization representing hematologists. It was founded in 1958. Its annual meeting is held in December of every year and has attracted more than 30,000 attendees. The society publishes th ...

(ASH) - Corporate supporter. *

Arthritis Society Arthritis is a term often used to mean any disorder that affects joints. Symptoms generally include joint pain and stiffness. Other symptoms may include redness, warmth, swelling, and decreased range of motion of the affected joints. In some ...

- National corporate partner. *

Canadian Society of Internal Medicine Canadians (french: Canadiens) are people identified with the country of Canada. This connection may be residential, legal, historical or cultural. For most Canadians, many (or all) of these connections exist and are collectively the source of ...

- Sponsor. *

European Society of Cardiology The European Society of Cardiology (ESC) is an independent non-profit, non-governmental professional association that works to advance the prevention, diagnosis and management of diseases of the heart and blood vessels, and improve scientific un ...

- Sponsor. * Spanish Cardiac Society - Partner.

Political lobbying

BIOTECanada BIOTECanada, or the Industrial Biotechnology Association of Canada, is a Canadian biotechnology industry association based in Ottawa, Ottawa, Ontario. It is an industry-funded membership organization composed of over 250 national and international ...

- Member company. BIOTECanada lobbies the Canadian government for policies favourable to the pharmaceutical industry. * Innovative Medicines Canada - Member. *

International Federation of Pharmaceutical Manufacturers & Associations The International Federation of Pharmaceutical Manufacturers & Associations (IFPMA) is a trade association that represents leading innovative pharmaceutical companies at the international level and in official relations with the United Nations. I ...

(IFPMA) - Member. *

National Health Council The National Health Council (NHC) is a nonprofit association of health organizations. Its members are national health-related organizations, including leading patient advocacy groups such as the American Cancer Society, the American Heart Associa ...

- Member. *

National Pharmaceutical Council National may refer to: Common uses * Nation or country ** Nationality – a ''national'' is a person who is subject to a nation, regardless of whether the person has full rights as a citizen Places in the United States * National, Maryland, ce ...

- Member. *

Personalized Medicine Coalition Personalization (broadly known as customization) consists of tailoring a service or a product to accommodate specific individuals, sometimes tied to groups or segments of individuals. A wide variety of organizations use personalization to improv ...

- Member. *

Pharmaceutical Advertising Advisory Board The Pharmaceutical Advertising Advisory Board (PAAB) is a Canadian not-for-profit organization based in Pickering, Ontario. Acting as a pseudo-regulatory body, PAAB offers review and pre-clearance services recognized by Health Canada to pharmaceu ...

- Client. * Pharmaceutical Research and Manufacturers of America - Member. * Research!America - Member.

Professional associations

Canadian Association of Emergency Physicians The Canadian Association of Emergency Physicians (CAEP) is the professional association of emergency physicians in Canada. It is also known in French as ''Association Canadienne des Médecins d'Urgence'' (''ACMU''). The official journal of the C ...

(CAEP) - Corporate partner. *

Canadian Rheumatology Association Canadians (french: Canadiens) are people identified with the country of Canada. This connection may be residential, legal, historical or cultural. For most Canadians, many (or all) of these connections exist and are collectively the source of ...

(CRA) - Corporate sponsor. * CARE Faculty - Sponsor. CARE is a Canadian coalition of medical specialists based in Oakville, Ontario. BMS was a sponsor for their 2021 Winter Hematology Update event. * Colorectal Cancer Canada (CRC) - Sponsor. *

Health Products Stewardship Association Health, according to the World Health Organization, is "a state of complete physical, mental and social well-being and not merely the absence of disease and infirmity".World Health Organization. (2006)''Constitution of the World Health Organiza ...

- Member.

Research and development

Lung Health Foundation The lungs are the primary organs of the respiratory system in humans and most other animals, including some snails and a small number of fish. In mammals and most other vertebrates, two lungs are located near the backbone on either side of t ...

- Partner. *

Multiple Sclerosis International Federation The Multiple Sclerosis International Federation (MSIF) was established in 1967 as an international body linking the activities of National MS societies around the world. The Federation seeks to work in worldwide partnership with Member Societies ...

- Partner. *

Pinnacle Research Group A pinnacle is an architecture, architectural element originally forming the cap or crown of a buttress or small Turret (architecture), turret, but afterwards used on parapets at the corners of towers and in many other situations. The pinnacle lo ...

- Sponsor. *

Radcliffe Cardiology Radcliffe or Radcliff may refer to: Places * Radcliffe Line, a border between India and Pakistan United Kingdom * Radcliffe, Greater Manchester ** Radcliffe Tower, the remains of a medieval manor house in the town ** Radcliffe tram stop * Ra ...

- Industry partner.

Scandals

Bristol-Myers Squibb,

Johns Hopkins University Johns Hopkins University (Johns Hopkins, Hopkins, or JHU) is a private university, private research university in Baltimore, Maryland. Founded in 1876, Johns Hopkins is the oldest research university in the United States and in the western hem ...

and the

Rockefeller Foundation The Rockefeller Foundation is an American private foundation and philanthropic medical research and arts funding organization based at 420 Fifth Avenue, New York City. The second-oldest major philanthropic institution in America, after the Carneg ...

are currently the subject of a $1 billion lawsuit from

Guatemala Guatemala ( ; ), officially the Republic of Guatemala ( es, República de Guatemala, links=no), is a country in Central America. It is bordered to the north and west by Mexico; to the northeast by Belize and the Caribbean; to the east by H ...

for "roles in a 1940s U.S. government experiment that infected hundreds of Guatemalans with

syphilis Syphilis () is a sexually transmitted infection caused by the bacterium ''Treponema pallidum'' subspecies ''pallidum''. The signs and symptoms of syphilis vary depending in which of the four stages it presents (primary, secondary, latent, an ...

". A previous suit against the

United States The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territorie ...

government was dismissed in 2011 for the

Guatemala syphilis experiments The Guatemala syphilis experiments were United States-led human experiments conducted in Guatemala from 1946 to 1948. The experiments were led by physician John Charles Cutler, who also participated in the late stages of the Tuskegee syphilis exp ...

when a judge determined that the U.S. government could not be held liable for actions committed outside of the U.S.

Notes and references

External links

*
Bristol-Myers Squibb worldwide locations

Bristol-Myers Squibb Influence and Lobbying Summary – Opensecrets.org
{{Authority control 1920s initial public offerings American companies established in 1887 Manufacturing companies based in New York City Multinational companies based in New York City Biotechnology companies of the United States Companies listed on the New York Stock Exchange Pharmaceutical companies established in 1887 Pharmaceutical companies of the United States Publicly traded companies based in New York City 1887 establishments in New York (state) National Medal of Technology recipients Orphan drug companies Life sciences industry

History

Squibb

Merger

2000 to 2010

2010 onward

Corporate acquisitions and divestments as Bristol Myers Squibb

List of mergers and acquisitions

Finances

Carbon footprint

Pharmaceuticals

Out of production

Divested brands

Products under development

Public-private engagement

Academia and education

Conferences and events

Healthcare

Media

Medical societies

Political lobbying

Professional associations

Research and development

Scandals

See also

Notes and references

External links