Bonferroni bound

In probability theory, Boole's inequality, also known as the union bound, says that for any finite or countable set of events, the probability that at least one of the events happens is no greater than the sum of the probabilities of the individual events. This inequality provides an upper bound on the probability of occurrence of at least one of a countable number of events in terms of the individual probabilities of the events. Boole's inequality is named for its discoverer George Boole.

Formally, for a countable set of events ''A''₁, ''A''₂, ''A''₃, ..., we have

:$\left(\bigcup_^ A_i \right) \le \sum_^ (A_i).$

In measure-theoretic terms, Boole's inequality follows from the fact that a measure (and certainly any probability measure) is ''σ''- sub-additive.

Proof

Proof using induction

Boole's inequality may be proved for finite collections of $n$ events using the method of induction.

For the $n=1$ case, it follows that

:$\mathbb P(A_1) \le \mathbb P(A_1).$

For the case $n$, we have

:$\left(\bigcup_^ A_i \right) \le \sum_^ (A_i).$

Since $\mathbb P(A \cup B) = \mathbb P(A) + \mathbb(B) - \mathbb(A \cap B),$ and because the union operation is associative, we have

:$\mathbb\left(\bigcup_^A_i\right) = \mathbb\left(\bigcup_^n A_i\right) + \mathbb(A_) -\mathbb\left(\bigcup_^n A_i \cap A_\right).$

Since

:$\left(\bigcup_^n A_i \cap A_\right) \ge 0,$

by the first axiom of probability, we have

:$\mathbb\left(\bigcup_^ A_i \right) \le \mathbb \left(\bigcup_^n A_i\right) + \mathbb(A_),$

and therefore

:$\mathbb\left(\bigcup_^ A_i \right) \le \sum_^ \mathbb(A_i) + \mathbb(A_) = \sum_^ \mathbb(A_i).$

Proof without using induction

For any events in $A_1, A_2, A_3, \dots$in our probability space we have

:$\mathbb\left(\bigcup_ A_i\right) \leq \sum_i \mathbb P(A_i).$

One of the axioms of a probability space is that if $B_1, B_2, B_3, \dots$ are ''disjoint'' subsets of the probability space then

:$\mathbb\left(\bigcup_ B_i\right) = \sum_i \mathbb P(B_i);$

this is called ''countable additivity.''

If $B \subset A,$ then $\mathbb P (B) \leq \mathbb P(A).$

Indeed, from the axioms of a probability distribution,

:$\mathbb P (A) = \mathbb P(B) + \mathbb P(A-B).$

Note that both terms on the right are nonnegative.

Now we have to modify the sets $A_i$, so they become disjoint.

:$B_i = A_i - \bigcup^_ A_j.$

So if $B_i \subset A_i$, then we know

:$\bigcup^_ B_i = \bigcup^_ A_i.$

Therefore, we can deduce the following equation

:$\mathbb P\left(\bigcup_iA_i\right) = \mathbb P\left(\bigcup_iB_i\right) = \sum_i \mathbb P (B_i) \leq \sum_i \mathbb P(A_i).$

Bonferroni inequalities

Boole's inequality may be generalized to find upper and lower bounds on the probability of finite unions of events. These bounds are known as Bonferroni inequalities, after Carlo Emilio Bonferroni; see .

Define

:$S_1 := \sum_^n (A_i),$

and

:$S_2 := \sum_ (A_i \cap A_j ),$

as well as

:$S_k := \sum_ (A_\cap \cdots \cap A_ )$

for all integers ''k'' in .

Then, for odd ''k'' in ,

:$\left( \bigcup_^n A_i \right) \le \sum_^k (-1)^ S_j,$

and for even ''k'' in ,

:$\left( \bigcup_^n A_i \right) \ge \sum_^k (-1)^ S_j.$

Boole's inequality is the initial case, ''k'' = 1. When ''k'' = ''n'', then equality holds and the resulting identity is the inclusion–exclusion principle.

Example

Suppose that you are estimating 5 parameters based on a random sample, and you can control each parameter separately. If you want your estimations of all five parameters to be good with a chance 95%, how should you do to each parameter?

Obviously, controlling each parameter good with a chance 95% is not enough because "all are good" is a subset of each event "Estimate ''i'' is good". We can use Boole's Inequality to solve this problem. By finding the complement of event "all fives are good", we can change this question into another condition:

''P( at least one estimation is bad) = 0.05 ≤ P( A₁ is bad) + P( A₂ is bad) + P( A₃ is bad) + P( A₄ is bad) + P( A₅ is bad)''

One way is to make each of them equal to 0.05/5 = 0.01, that is 1%. In another word, you have to guarantee each estimate good to 99%( for example, by constructing a 99% confidence interval) to make sure the total estimation to be good with a chance 95%. This is called Bonferroni Method of simultaneous inference.

See also

* Diluted inclusion–exclusion principle
* Schuette–Nesbitt formula
* Boole–Fréchet inequalities
* Probability of the union of pairwise independent events

References

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{{PlanetMath attribution, id=6049, title=Bonferroni inequalities

Probabilistic inequalities
Statistical inequalities