BoneSupport AB is a Swedish biotech company active at the Ideon Science Park in the university town of
Lund
Lund (, , ) is a city in the southern Swedish provinces of Sweden, province of Scania, across the Øresund, Öresund strait from Copenhagen. The town had 91,940 inhabitants out of a municipal total of 121,510 . It is the seat of Lund Municipali ...
in
Skåne
Scania, also known by its native name of Skåne (, ), is the southernmost of the historical provinces (''landskap'') of Sweden. Located in the south tip of the geographical region of Götaland, the province is roughly conterminous with Skåne C ...
, Sweden, founded in 1999 by Lars Lidgren, Professor of Orthopedic Surgery and Academic Head of Department at
Lund University
, motto = Ad utrumque
, mottoeng = Prepared for both
, established =
, type = Public research university
, budget = SEK 9 billion SEK 500 million in
venture capital
Venture capital (often abbreviated as VC) is a form of private equity financing that is provided by venture capital firms or funds to startups, early-stage, and emerging companies that have been deemed to have high growth potential or which ha ...
from inter alia
HealthCap HealthCap is a specialized provider of venture capital within life sciences. HealthCap invests in innovative companies with focus on therapeutics. As of 2017, HealthCap has invested in over 100 companies since inception and completed initial public ...
,
Lundbeck
H. Lundbeck A/S (commonly known simply as Lundbeck) is a Danish international pharmaceutical company engaged in the research, development, manufacturing, marketing and sale of pharmaceuticals across the world. The company’s products are target ...
''Cerament'' is a synthetic, injectable, osteoconductive biomaterial, which actively promotes
bone healing
Bone healing, or fracture healing, is a proliferative physiological process in which the body facilitates the repair of a bone fracture.
Generally, bone fracture treatment consists of a doctor reducing (pushing) displaced bones back into place ...
and is utilized as a bone substitute, when
bone grafting
Bone grafting is a surgical procedure that replaces missing bone in order to repair bone fractures that are extremely complex, pose a significant health risk to the patient, or fail to heal properly. Some small or acute fractures can be cured wit ...
is needed. Full remodeling to healthy bone occurs between 6 and 12 months.Osteotomy Of Distal Radius Fracture Malunion Using a Fast Remodeling Bone Substitute Consisting of Calcium Sulphate and Calcium Phosphate. Abramo A, Geijer M, Kopylov P, Tägil M. J of Biomed Materials Research (B) Nov 2009 281-286
Cerament is used for the treatment of fragility fractures caused by
Osteoporosis
Osteoporosis is a systemic skeletal disorder characterized by low bone mass, micro-architectural deterioration of bone tissue leading to bone fragility, and consequent increase in fracture risk. It is the most common reason for a broken bone ...
, to fill bone voids or gaps caused by trauma or orthopedic surgical procedures for e.g., benign tumors, and for augmentation of fracture repair.
Cerament can be loaded with
antibiotics
An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention o ...
like
Gentamicin
Gentamicin is an antibiotic used to treat several types of bacterial infections. This may include bone infections, endocarditis, pelvic inflammatory disease, meningitis, pneumonia, urinary tract infections, and sepsis among others. It is not e ...
(Cerament with gentamicin is not FDA approved), thereby protecting bone healing in patients with bone infections (
osteomyelitis
Osteomyelitis (OM) is an infection of bone. Symptoms may include pain in a specific bone with overlying redness, fever, and weakness. The long bones of the arms and legs are most commonly involved in children e.g. the femur and humerus, while the ...
)
Cerament bone void filler received approval by the U.S.
Food and Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is respon ...
(FDA) for sale in the United States in 2005 and CE-marking in 2009. Cerament spine support received its CE mark in 2008.
In September 2012, BoneSupport entered a distribution agreement with the major medical device manufacturer
Biomet
Biomet, Inc., was a medical device manufacturer located in the Warsaw, Indiana, business cluster. The company specialized in reconstructive products for orthopedic surgery, neurosurgery, craniomaxillofacial surgery and operating room supplies. In ...
who have exclusive distribution rights of the Cerament bone void filler product range in the United States of America and Canada. This agreement is expected to accelerate the usage of Bonesupport’s bone void filler (Cerament) product line in orthopaedic operations.
In May 2018 Bonesupport ended their U.S. distribution agreement with ZimmerBiomet which dated back to 2012. They took back distribution in the US market and now work through a network of independent distributors.
Cerament G was named a breakthrough device in 2020 and 2021 by the FDA. The Fortify IDE study completed follow up in 2021 and will be filed with the FDA in Q4 2022. Cerament G has been approved in Europe dating back to 2013.
Initial public offering (IPO)
On 11 June 2017, BoneSupport AB's Board of Directors applied for the company’s shares to be admitted to trading on Nasdaq Stockholm’s main market. Nasdaq Stockholm approved the Company’s application subject to customary conditions. The first day of trading in the Company’s shares was on 21 June 2017.