Betaenone C, like other betaenones ( A and B), is a

secondary metabolite Secondary metabolites, also called specialised metabolites, toxins, secondary products, or natural products, are organic compounds produced by any lifeform, e.g. bacteria, fungi, animals, or plants, which are not directly involved in the norm ...

isolated from the

fungus A fungus ( : fungi or funguses) is any member of the group of eukaryotic organisms that includes microorganisms such as yeasts and molds, as well as the more familiar mushrooms. These organisms are classified as a kingdom, separately from th ...

Pleospora betae ''Pleospora betae'' is a plant pathogen infecting beet. It contains the chemical substances betaenone A, B and C. Pleospora betae develops on dead beet residues and is a marsupial stage of the Phoma betae anamorph, parasitizing on beets and ca ...

'', a plant pathogen. Of the seven phytotoxins isolated in fungal leaf spots from

sugar beet A sugar beet is a plant whose root contains a high concentration of sucrose and which is grown commercially for sugar production. In plant breeding, it is known as the Altissima cultivar group of the common beet (''Beta vulgaris''). Together wi ...

(''Beta vulgaris''), it showed 89%

growth inhibition ''Growth inhibition'' (GI) is a medical term pertaining to cancer therapy and the specific reduction in growth of tumors and oncogene cells by a chemical compound, mechanical therapy (e.g. electroporation), radiation, gene therapy, protein therapy, ...

. Betaenone C has been shown to act by inhibiting

RNA Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation and expression of genes. RNA and deoxyribonucleic acid ( DNA) are nucleic acids. Along with lipids, proteins, and carbohydra ...

and

protein synthesis Protein biosynthesis (or protein synthesis) is a core biological process, occurring inside Cell (biology), cells, homeostasis, balancing the loss of cellular proteins (via Proteolysis, degradation or Protein targeting, export) through the product ...

References

Decalins Tertiary alcohols Cyclic ketones Primary alcohols 3-Hydroxypropenals {{Ketone-stub