The Basic Amino Acid Antiporter (ArcD) family (TC# 2.A.118) is a constituent of the
IT superfamily. This family consists of proteins from
Gram-negative
Gram-negative bacteria are bacteria that do not retain the crystal violet stain used in the Gram staining method of bacterial differentiation. They are characterized by their cell envelopes, which are composed of a thin peptidoglycan cell wall ...
and
Gram-positive bacteria
In bacteriology, gram-positive bacteria are bacteria that give a positive result in the Gram stain test, which is traditionally used to quickly classify bacteria into two broad categories according to their type of cell wall.
Gram-positive bact ...
(e.g., ''
Streptococcus
''Streptococcus'' is a genus of gram-positive ' (plural ) or spherical bacteria that belongs to the family Streptococcaceae, within the order Lactobacillales (lactic acid bacteria), in the phylum Bacillota. Cell division in streptococci occurs ...
'', ''
Escherichia
''Escherichia'' () is a genus of Gram-negative, non- spore-forming, facultatively anaerobic, rod-shaped bacteria from the family Enterobacteriaceae. In those species which are inhabitants of the gastrointestinal tracts of warm-blooded animals, ...
'', ''
Salmonella
''Salmonella'' is a genus of rod-shaped (bacillus) Gram-negative bacteria of the family Enterobacteriaceae. The two species of ''Salmonella'' are ''Salmonella enterica'' and ''Salmonella bongori''. ''S. enterica'' is the type species and is fur ...
'', ''
Fusobacterium
''Fusobacterium'' is a genus of anaerobic, Gram-negative, non-sporeforming bacteria belonging to Gracilicutes. Individual cells are slender, rod-shaped bacilli with pointed ends.
Strains of ''Fusobacterium'' cause several human diseases, includin ...
'' and ''
Borrelia
''Borrelia'' is a genus of bacteria of the spirochete phylum. Several species cause Lyme disease, also called Lyme borreliosis, a zoonotic, vector-borne disease transmitted by ticks. Other species of ''Borrelia'' cause relapsing fever, and are tr ...
'' species). The proteins are of about 480 amino acyl residues (aas) in length and have 10-12 putative transmembrane segments (TMSs). Functionally characterized homologues are in the DcuC
TC #2.A.61 and ArsB
TC #2.A.4 families. Some members of the family probably catalyze arginine/ornithine or citrulline/ornithine antiport.
See also
*
Ion transporter superfamily
The ion transporter (IT) superfamily is a protein superfamily, superfamily of secondary carriers that transport proteins, transport charged substrates.
Families
As of early 2016, the currently recognized and functionally defined families that ...
*
Amino acid transporter
An amino acid transporter is a membrane transport protein that transports amino acids. They are mainly of the solute carrier family.
Families
There are several families that function in amino acid transport, some of these include:
TC# 2.A.3- ...
s
*
DcuC
*
ArsB and ArsAB
*
Transporter Classification Database
References
Protein families
Membrane proteins
Transmembrane proteins
Transmembrane transporters
Transport proteins
Integral membrane proteins
{{membrane-protein-stub