Barry Spencer Coller is an American physician known for his research in

platelet Platelets, also called thrombocytes (from Greek θρόμβος, "clot" and κύτος, "cell"), are a component of blood whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby ini ...

physiology and for inventing the

Abciximab Abciximab, a glycoprotein IIb/IIIa receptor antagonist manufactured by Janssen Biologics BV and distributed by Eli Lilly under the trade name ReoPro, is a platelet aggregation inhibitor mainly used during and after coronary artery procedures lik ...

. He is the

David Rockefeller David Rockefeller (June 12, 1915 – March 20, 2017) was an American investment banker who served as chairman and chief executive of Chase Manhattan Corporation. He was the oldest living member of the third generation of the Rockefeller family, ...

Professor, Physician-In-Chief, and Vice President for Medical Affairs at

Rockefeller University The Rockefeller University is a private biomedical research and graduate-only university in New York City, New York. It focuses primarily on the biological and medical sciences and provides doctoral and postdoctoral education. It is classif ...

Biography

Coller grew up in

Queens, New York Queens is a borough of New York City, coextensive with Queens County, in the U.S. state of New York. Located on Long Island, it is the largest New York City borough by area. It is bordered by the borough of Brooklyn at the western tip of Long I ...

to a family of lawyers and physicians. He graduated from Columbia College,

Phi Beta Kappa The Phi Beta Kappa Society () is the oldest academic honor society in the United States, and the most prestigious, due in part to its long history and academic selectivity. Phi Beta Kappa aims to promote and advocate excellence in the liberal a ...

, in 1966 and his M.D. from

New York University School of Medicine NYU Grossman School of Medicine is a medical school of New York University, a private research university in New York City. It was founded in 1841 and is one of two medical schools of the university, with the other being the Long Island School of ...

in 1970. He finished his residency at

Bellevue Hospital Bellevue Hospital (officially NYC Health + Hospitals/Bellevue and formerly known as Bellevue Hospital Center) is a hospital in New York City and the oldest public hospital in the United States. One of the largest hospitals in the United States b ...

and worked as a clinical associate and staff physician in the

hematology Hematology ( always spelled haematology in British English) is the branch of medicine concerned with the study of the cause, prognosis, treatment, and prevention of diseases related to blood. It involves treating diseases that affect the produc ...

division of the

National Institutes of Health The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late ...

(NIH). Upon leaving NIH, he joined

Stony Brook School of Medicine The Renaissance School of Medicine (RSOM) is the graduate medical school of Stony Brook University located in the hamlet of Stony Brook on Long Island, New York. Founded in 1971, RSOM is consistently ranked the top public medical school in New ...

, becoming Distinguished Service Professor in 1993. His research has focused on investigating the role of blood platelets and the mechanisms of blood cell adhesion in vascular disease and designing new therapies for thrombotic diseases such as stroke and heart attack. He is credited for having developed a monoclonal antibody that inhibits platelet function, which was eventually developed into

, which, since its approval by the

Food and Drug Administration The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is respon ...

(FDA) in 1994, has been used to treat more than 2 million patients. Coller joined the faculty of

Mount Sinai School of Medicine The Icahn School of Medicine at Mount Sinai (ISMMS or Mount Sinai), formerly the Mount Sinai School of Medicine, is a private medical school in New York City. It is the academic teaching arm of the Mount Sinai Health System, which manages eigh ...

in 1994 and was Murray M. Rosenberg Professor of Medicine and Chairman of the

Samuel Bronfman Samuel Bronfman, (February 27, 1889 – July 10, 1971) was a Canadian businessman and philanthropist. He founded Distillers Corporation Limited, and is a member of the Canadian Bronfman family. Biography Samuel Bronfman was born in Otaci, So ...

Department of Medicine until 2001, when he became the university's inaugural David Rockefeller Professor, Physician-in-Chief of

Rockefeller University Hospital The Rockefeller University is a private biomedical research and graduate-only university in New York City, New York. It focuses primarily on the biological and medical sciences and provides doctoral and postdoctoral education. It is classifie ...

and Vice President of

for Medical Affairs. In 2019, Coller was named a member of the advisory panel that examined

Duke University Duke University is a private research university in Durham, North Carolina. Founded by Methodists and Quakers in the present-day city of Trinity in 1838, the school moved to Durham in 1892. In 1924, tobacco and electric power industrialist James ...

's medical research integrity after it was revealed that a Duke employee falsified data to get $112.5 million in NIH and

EPA The Environmental Protection Agency (EPA) is an independent executive agency of the United States federal government tasked with environmental protection matters. President Richard Nixon proposed the establishment of EPA on July 9, 1970; it be ...

grant between 2006 and 2018.

Awards and honors

He was the recipient of the

Robert J. and Claire Pasarow Foundation Medical Research Award The Robert J. And Claire Pasarow Foundation Medical Research Awards were awarded annually for distinguished accomplishment in areas of investigation that included neuropsychiatry, cardiovascular disease, and cancer research. The program ran from 1 ...

in 2004, the

Warren Alpert Foundation Prize The Warren Alpert Foundation Prize is awarded annually to scientist(s) whose scientific achievements have led to the prevention, cure or treatment of human diseases or disorders, and/or whose research constitutes a seminal scientific finding that ho ...

in 2001, the

Karl Landsteiner Memorial Award The Karl Landsteiner Memorial Award is a scientific award given by the American Association of Blood Banks (AABB) to scientists with "an international reputation in transfusion medicine or cellular therapies" "whose original research resulted in an ...

in 2013, and the George M. Kober Lectureship in 2012. Coller was named to the

National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...

in 2003, the

National Academy of Medicine The National Academy of Medicine (NAM), formerly called the Institute of Medicine (IoM) until 2015, is an American nonprofit, non-governmental organization. The National Academy of Medicine is a part of the National Academies of Sciences, En ...

in 1999, and the

American Academy of Arts and Sciences The American Academy of Arts and Sciences (abbreviation: AAA&S) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and ...

. He was a recipient of the

Guggenheim Fellowship Guggenheim Fellowships are grants that have been awarded annually since by the John Simon Guggenheim Memorial Foundation to those "who have demonstrated exceptional capacity for productive scholarship or exceptional creative ability in the ar ...

in 1982.

Personal life

Coller is married to Bobbi Coller, an art historian and independent curator who is the chairperson of the advisory board of the

Pollock-Krasner House and Study Center In November 1945, Jackson Pollock and his wife Lee Krasner moved to what is now known as the Pollock-Krasner House and Studio in Springs in the town of East Hampton on Long Island, New York. The wood-frame house on with a nearby barn is o ...

. The Barry and Bobbi Coller Rare Book Reading Room at the

New York Academy of Medicine The New York Academy of Medicine (the Academy) is a health policy and advocacy organization founded in 1847 by a group of leading New York metropolitan area physicians as a voice for the medical profession in medical practice and public health ...

is named after the couple.

References

{{DEFAULTSORT:Coller, Barry S. Living people Columbia College (New York) alumni People from Queens, New York New York University Grossman School of Medicine alumni Rockefeller University faculty Stony Brook University faculty Icahn School of Medicine at Mount Sinai faculty 20th-century American physicians 21st-century American physicians Physicians from New York City Year of birth missing (living people) Presidents of the American Society of Hematology Members of the National Academy of Medicine