An antiflatulent (or deflatulent) agent is a drug used for the alleviation or prevention of excessive intestinal gas, i.e., flatulence.
Mechanisms of action
Preventing gas
* Enzymes – Enzyme-based dietary supplements break down indigestible substances and prevent these substances from reaching the
large intestine
The large intestine, also known as the large bowel, is the last part of the gastrointestinal tract and of the digestive system in tetrapods. Water is absorbed here and the remaining waste material is stored in the rectum as feces before being re ...
intact – where anaerobic bacteria produce gas. Substances indigestible by humans are usually present in foods associated with flatulence, like
bean
A bean is the seed of several plants in the family Fabaceae, which are used as vegetables for human or animal food. They can be cooked in many different ways, including boiling, frying, and baking, and are used in many traditional dishes thr ...
s. When these substances reach the large intestine intact, they may be fermented by intestinal bacteria, thereby causing gas production. These supplements are usually taken with foods associated with flatulence. It is important to take the appropriate enzyme with the appropriate food. When consuming beans and other vegetables high in
complex carbohydrate
In organic chemistry, a carbohydrate () is a biomolecule consisting of carbon (C), hydrogen (H) and oxygen (O) atoms, usually with a hydrogen–oxygen atom ratio of 2:1 (as in water) and thus with the empirical formula (where ''m'' may or may ...
kombu
''Konbu'' (from ja, 昆布, konbu or kombu) is edible kelp mostly from the family Laminariaceae and is widely eaten in East Asia. It may also be referred to as ''dasima'' ( ko, 다시마) or ''haidai'' ().
Kelp features in the diets of many ...
. Additionally, for individuals with
lactose intolerance
Lactose intolerance is a common condition caused by a decreased ability to digest lactose, a sugar found in dairy products. Those affected vary in the amount of lactose they can tolerate before symptoms develop. Symptoms may include abdominal p ...
, taking a
lactase
Lactase is an enzyme produced by many organisms. It is located in the brush border of the small intestine of humans and other mammals. Lactase is essential to the complete digestion of whole milk; it breaks down lactose, a sugar which gives m ...
-containing product with lactose-containing foodstuffs may reduce flatulence.
* Herbal inhibitors – Many herbal substances have been observed since antiquity for reducing flatulence, particularly gas from eating legumes.
Cloves
Cloves are the aromatic flower buds of a tree in the family Myrtaceae, ''Syzygium aromaticum'' (). They are native to the Maluku Islands (or Moluccas) in Indonesia, and are commonly used as a spice, flavoring or fragrance in consumer products, ...
cinnamon
Cinnamon is a spice obtained from the inner bark of several tree species from the genus '' Cinnamomum''. Cinnamon is used mainly as an aromatic condiment and flavouring additive in a wide variety of cuisines, sweet and savoury dishes, break ...
, and garlic are potent in reducing gas. The potency of garlic increases when heated, whereas the potency of cinnamon decreases. Other spices have a lesser effect in reducing gas, including turmeric,
black pepper
Black pepper (''Piper nigrum'') is a flowering vine in the family Piperaceae, cultivated for its fruit, known as a peppercorn, which is usually dried and used as a spice and seasoning. The fruit is a drupe (stonefruit) which is about in diame ...
,
asafoetida
Asafoetida (; also spelled asafetida)
is the dried latex (gum oleoresin) exuded from the rhizome or tap root of several species of ''Ferula'', perennial herbs growing tall. They are part of the celery family, Umbelliferae. Asafoetida is thou ...
aniseed
Anise (; '), also called aniseed or rarely anix is a flowering plant in the family Apiaceae native to Eurasia.
The flavor and aroma of its seeds have similarities with some other spices and herbs, such as star anise, fennel, licorice, and ta ...
,
ajowan
Ajwain, ajowan (), or ''Trachyspermum ammi''—also known as ajowancaraway, omam (in Tamil), thymol seeds, bishop's weed, or carom—is an annual herb in the family Apiaceae. Both the leaves and the seed‑like fruit (often mistakenly called se ...
, and
cardamom
Cardamom (), sometimes cardamon or cardamum, is a spice made from the seeds of several plants in the genera ''Elettaria'' and ''Amomum'' in the family Zingiberaceae. Both genera are native to the Indian subcontinent and Indonesia. They are re ...
For the ''alleviation'' of flatulence, an antifoaming agent such as
simethicone
Simeticone ( INN), also known as simethicone ( USAN), is an anti-foaming agent used to reduce bloating, discomfort or pain caused by excessive gas.
Medical uses
Simeticone is used to relieve the symptoms of excessive gas in the gastrointestina ...
may be taken orally. This agent will coalesce the smaller gas bubbles into larger bubbles, thereby easing the release of gas within the gastrointestinal tract via
burping
Burping (also called belching and eructation) is the release of gas from the upper digestive tract (esophagus and stomach) of animals through the mouth. It is usually audible.
In humans, burping can be caused by normal eating processes, or as ...
or flatulence.
Classification
Antifoaming agents
*
Simethicone
Simeticone ( INN), also known as simethicone ( USAN), is an anti-foaming agent used to reduce bloating, discomfort or pain caused by excessive gas.
Medical uses
Simeticone is used to relieve the symptoms of excessive gas in the gastrointestina ...
(also marketed under the name "Gas-X" in some countries)
Lactase
Lactase is an enzyme produced by many organisms. It is located in the brush border of the small intestine of humans and other mammals. Lactase is essential to the complete digestion of whole milk; it breaks down lactose, a sugar which gives m ...
(brand Lactaid)
Herbal antiflatulents
*
Epazote
''Dysphania ambrosioides'', formerly ''Chenopodium ambrosioides'', known as Jesuit's tea, Mexican-tea, ''payqu'' ''(paico)'', ''epazote'', ''mastruz'', or ''herba sanctæ Mariæ'', is an annual or short-lived perennial herb native to Central A ...
is claimed to have antiflatulent properties.
*
Asafoetida
Asafoetida (; also spelled asafetida)
is the dried latex (gum oleoresin) exuded from the rhizome or tap root of several species of ''Ferula'', perennial herbs growing tall. They are part of the celery family, Umbelliferae. Asafoetida is thou ...
reduces the growth of indigenous microflora in the gut thereby reducing flatulence.S. K. GARG, A. C. BANERJEA, J. VERMA. and M. J. ABRAHAM, EFFECT OF VARIOUS TREATMENTS OF PULSES ON IN VITRO GAS PRODUCTION BY SELECTED INTESTINAL CLOSTRIDIA. Journal of Food Science, Volume 45, Issue 6 (p 1601-1602).
See also
*
Carminative A carminative, also known as carminativum ( plural carminativa), is a herb or preparation intended to either prevent formation of gas in the gastrointestinal tract or facilitate the expulsion of said gas, thereby combatting flatulence.
Name
The w ...