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Atypical adenomatous hyperplasia is a subtype of
pneumocytic hyperplasia Pneumocytic hyperplasia is an hyperplasia of pneumocytes lining pulmonary alveoli. Types *Pulmonary atypical adenomatous hyperplasia *Multifocal micronodular pneumocyte hyperplasia References

Pulmonary lesion {{med-sign-stub ...
in the lung. It can be a precursor lesion of in situ adenocarcinoma of the lung (
bronchioloalveolar carcinoma Adenocarcinoma in situ (AIS) of the lung —previously included in the category of "bronchioloalveolar carcinoma" (BAC)—is a subtype of lung adenocarcinoma. It tends to arise in the distal bronchioles or alveoli and is defined by a non-invasive ...
). In prostate tissue biopsy, it can be confused for adenocarcinoma of the prostate. The needle biopsy rate is less than 1%.


Pathology


Morphological differential diagnosis

* Multifocal micronodular pneumocyte hyperplasia (MMPH) * in situ pulmonary adenocarcinoma (
bronchioloalveolar carcinoma Adenocarcinoma in situ (AIS) of the lung —previously included in the category of "bronchioloalveolar carcinoma" (BAC)—is a subtype of lung adenocarcinoma. It tends to arise in the distal bronchioles or alveoli and is defined by a non-invasive ...
– BAC)


Variants

* multiple atypical adenomatous hyperplasia * disseminated AAH


Histopathological images

Image:Pulmonary_adeocaricnoma_(1)_localized_noninvasive_type.jpg Image:Pulmonary adeocaricnoma (2) localized noninvasive type.jpg Image:Pulmonary adeocaricnoma (3) localized noninvasive type.jpg Image:Pulmonary_adeocaricnoma_(4)_localized_noninvasive_type.jpg


See also

* EGFR *
KRAS ''KRAS'' ( Kirsten rat sarcoma virus) is a gene that provides instructions for making a protein called K-Ras, a part of the RAS/MAPK pathway. The protein relays signals from outside the cell to the cell's nucleus. These signals instruct the cel ...


References

Pulmonary lesion {{med-sign-stub