Arthur Lindo Patterson
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Arthur Lindo Patterson (23 July 1902, Nelson, New Zealand - 6 November 1966,
Philadelphia, Pennsylvania Philadelphia, often called Philly, is the largest city in the Commonwealth of Pennsylvania, the sixth-largest city in the U.S., the second-largest city in both the Northeast megalopolis and Mid-Atlantic regions after New York City. Sinc ...
) was a pioneering British
X-ray crystallographer X-ray crystallography is the experimental science determining the atomic and molecular structure of a crystal, in which the crystalline structure causes a beam of incident X-rays to diffract into many specific directions. By measuring the angles ...
. Patterson was born to British parents in New Zealand in 1902. Shortly afterwards the family moved to Montreal, Canada and later to London, England. In 1920 Patterson moved to Canada for college at
McGill University McGill University (french: link=no, Université McGill) is an English-language public research university located in Montreal, Quebec Montreal ( ; officially Montréal, ) is the second-most populous city in Canada and most populous ...
, Montreal. Firstly he concentrated on Mathematics and but then changed his major to Physics. He received his bachelor's degree in 1923 and a master's in 1924. His master's thesis was on the production of hard X-rays by interaction of
radium Radium is a chemical element with the symbol Ra and atomic number 88. It is the sixth element in group 2 of the periodic table, also known as the alkaline earth metals. Pure radium is silvery-white, but it readily reacts with nitrogen (rathe ...
β rays with solids. From 1924 to 1926 he worked in London in the laboratory of W. H. Bragg, where he learnt the art of crystal structure analysis. In 1926 Patterson moved to the
Kaiser Wilhelm Institute The Kaiser Wilhelm Society for the Advancement of Science (German: ''Kaiser-Wilhelm-Gesellschaft zur Förderung der Wissenschaften'') was a German scientific institution established in the German Empire in 1911. Its functions were taken over by ...
for Fibrous Materials Chemistry (later the Fritz Haber Institute) in the Dahlem neighbourhood of Berlin, where he worked on the X-ray crystallography of
cellulose Cellulose is an organic compound with the formula , a polysaccharide consisting of a linear chain of several hundred to many thousands of β(1→4) linked D-glucose units. Cellulose is an important structural component of the primary cell w ...
fibres. In Berlin he had the fortune to meet the scientific elite of the time, which included Max von Laue,
Albert Einstein Albert Einstein ( ; ; 14 March 1879 – 18 April 1955) was a German-born theoretical physicist, widely acknowledged to be one of the greatest and most influential physicists of all time. Einstein is best known for developing the theory ...
,
Max Planck Max Karl Ernst Ludwig Planck (, ; 23 April 1858 – 4 October 1947) was a German theoretical physicist whose discovery of energy quanta won him the Nobel Prize in Physics in 1918. Planck made many substantial contributions to theoretical p ...
, Walther Nernst,
Hans Bethe Hans Albrecht Bethe (; July 2, 1906 – March 6, 2005) was a German-American theoretical physicist who made major contributions to nuclear physics, astrophysics, quantum electrodynamics, and solid-state physics, and who won the 1967 Nobel ...
,
Otto Hahn Otto Hahn (; 8 March 1879 – 28 July 1968) was a German chemist who was a pioneer in the fields of radioactivity and radiochemistry. He is referred to as the father of nuclear chemistry and father of nuclear fission. Hahn and Lise Meitner ...
, Lise Meitner and Peter Pringsheim. In 1927 he returned to McGill, finishing his work for the PhD degree in 1928. From 1933 to 1946, Patterson was a visiting researcher in the laboratory of Bertram Eugene Warren (1902–1991) at MIT. It was during this time that he published his famous function, now called the
Patterson function The Patterson function is used to solve the phase problem in X-ray crystallography. It was introduced in 1935 by Arthur Lindo Patterson while he was a visiting researcher in the laboratory of Bertram Eugene Warren at MIT. The Patterson function is ...
, which subsequently developed into an extremely important theoretical tool in X-ray crystal structure analysis, especially when one or more heavy atoms are present in the structure. From 1936 to 1949, he taught at
Bryn Mawr College Bryn Mawr College ( ; Welsh: ) is a women's liberal arts college in Bryn Mawr, Pennsylvania. Founded as a Quaker institution in 1885, Bryn Mawr is one of the Seven Sister colleges, a group of elite, historically women's colleges in the United ...
, and from 1949 to 1966, he was a faculty member at the Institute for Cancer Research, now the
Fox Chase Cancer Center Fox Chase Cancer Center is a National Cancer Institute-designated Comprehensive Cancer Center research facility and hospital located in the Fox Chase section of Philadelphia, Pennsylvania, United States. The main facilities of the center are loca ...
in Philadelphia.


Achievements

His work led to some of the first important contributions to the theory of particle-size line broadening. In 1934, while at
Massachusetts Institute of Technology The Massachusetts Institute of Technology (MIT) is a private land-grant research university in Cambridge, Massachusetts. Established in 1861, MIT has played a key role in the development of modern technology and science, and is one of the ...
, he developed a method of solving
crystal structure In crystallography, crystal structure is a description of the ordered arrangement of atoms, ions or molecules in a crystalline material. Ordered structures occur from the intrinsic nature of the constituent particles to form symmetric patterns ...
s, the
Patterson function The Patterson function is used to solve the phase problem in X-ray crystallography. It was introduced in 1935 by Arthur Lindo Patterson while he was a visiting researcher in the laboratory of Bertram Eugene Warren at MIT. The Patterson function is ...
, which involves the summing of the Fourier series in two and three dimensions. In addition he became concerned about the problem of uniqueness of the deconvolution of the Patterson function and was able to show that under some conditions several different atomic arrangements — homometric structures — could exist that would give the same Patterson function and therefore the same intensities in
reciprocal space In physics, the reciprocal lattice represents the Fourier transform of another lattice (usually a Bravais lattice). In normal usage, the initial lattice (whose transform is represented by the reciprocal lattice) is usually a periodic spatial fu ...
.


References


External links


His obituary in Acta Crystallographica


See also

*
Patterson function The Patterson function is used to solve the phase problem in X-ray crystallography. It was introduced in 1935 by Arthur Lindo Patterson while he was a visiting researcher in the laboratory of Bertram Eugene Warren at MIT. The Patterson function is ...
*
Structure factor In condensed matter physics and crystallography, the static structure factor (or structure factor for short) is a mathematical description of how a material scatters incident radiation. The structure factor is a critical tool in the interpretation ...
{{DEFAULTSORT:Patterson 1902 births 1966 deaths English scientists British scientists American crystallographers McGill University Faculty of Science alumni Bryn Mawr College faculty Scientists from Philadelphia British emigrants to the United States British expatriates in New Zealand British expatriates in Canada Fox Chase Cancer Center people