''Aquaparamyxovirus'' is a genus of

virus A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsky's 1 ...

es in the family ''

Paramyxoviridae ''Paramyxoviridae'' (from Ancient Greek, Greek ''para-'' “by the side of” and ''myxa'' “mucus”) is a family of negative-strand RNA viruses in the order ''Mononegavirales''. Vertebrates serve as natural hosts. Diseases associated with this ...

'', order ''

Mononegavirales ''Mononegavirales'' is an order of negative-strand RNA viruses which have nonsegmented genomes. Some common members of the order are Ebola virus, human respiratory syncytial virus, measles virus, mumps virus, Nipah virus, and rabies virus. All of ...

''. The genus includes two species. Fish serve as the natural hosts for AsaPV, in which the virus may cause proliferative gill inflammation.

Taxonomy

The genus contains the following species: * '' Oncorhynchus aquaparamyxovirus'' * '' Salmo aquaparamyxovirus''

Structure

Viruses of the genus ''Aquaparamyxovirus'' produce virions that are enveloped, with spherical geometries. The diameter is around 150 nm. Genomes are linear, around 17 kb in length. The genome codes for 9 proteins.

Life cycle

Viral replication is

cytoplasm In cell biology, the cytoplasm is all of the material within a eukaryotic cell, enclosed by the cell membrane, except for the cell nucleus. The material inside the nucleus and contained within the nuclear membrane is termed the nucleoplasm. The ...

ic. Entry into the host cell is achieved by attachment to host

cell surface receptor Cell surface receptors (membrane receptors, transmembrane receptors) are receptors that are embedded in the plasma membrane of cells. They act in cell signaling by receiving (binding to) extracellular molecules. They are specialized integral m ...

s through HN glycoprotein. Fusion with the

plasma membrane The cell membrane (also known as the plasma membrane (PM) or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates and protects the interior of all cells from the outside environment (t ...

; ribonucleocapsid is released in the cytoplasm. Sequential transcription, viral mRNAs are capped and polyadenylated in the cytoplasm. Replication presumably starts when enough

nucleoprotein Nucleoproteins are proteins conjugated with nucleic acids (either DNA or RNA). Typical nucleoproteins include ribosomes, nucleosomes and viral nucleocapsid proteins. Structures Nucleoproteins tend to be positively charged, facilitating inte ...

is present to encapsidate neo-synthesized

antigenome {{Short pages monitor 3' direction along ...

. The virus exits the host cell by budding. Fish serve as the natural host.

References

External links

ICTV Report: ''Paramyxoviridae''

{{Taxonbar, from=Q18813847, from2=Q29004333 Paramyxoviridae Virus genera