Anne O'Tate
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Anne O'Tate is a free, web-based application that analyses sets of records identified on
PubMed PubMed is an openly accessible, free database which includes primarily the MEDLINE database of references and abstracts on life sciences and biomedical topics. The United States National Library of Medicine (NLM) at the National Institute ...
, the
bibliographic database A bibliographic database is a database of bibliographic records. This is an organised online collection of references to published written works like academic journal, journal and newspaper articles, conference proceedings, reports, government an ...
of articles from over 5,500 biomedical journals worldwide. While PubMed has its own wide range of search options to identify sets of records relevant to a researchers query it lacks the ability to analyse these sets of records further, a process for which the terms
text mining Text mining, text data mining (TDM) or text analytics is the process of deriving high-quality information from text. It involves "the discovery by computer of new, previously unknown information, by automatically extracting information from differe ...
and
drill down Data drilling (also drilldown) refers to any of various operations and transformations on tabular, relational, and multidimensional data. The term has widespread use in various contexts, but is primarily associated with specialized software design ...
have been used. Anne O'Tate is able to perform such analysis and can process sets of up to 25,000 PubMed records.


Description

Once a set of articles has been identified using Anne O’Tate with its PubMed-like interface and search syntax, the set can be analysed and words and concepts mentioned in specific 'fields' (sections) of PubMed records can be displayed in order of frequency. ‘Fields’ which Anne O’Tate can display in this manner are:


Topics (MeSH)

This option may help to identify possible
Medical Subject Headings Medical Subject Headings (MeSH) is a comprehensive controlled vocabulary for the purpose of indexing Academic journal, journal articles and books in the Life science, life sciences. It serves as a thesaurus of index terms that facilitates searc ...
(known as MeSH terms, but called ‘Topics’ by Anne O’Tate) for a subject for which no corresponding subject heading or ‘entry term’ (cross-references to preferred MeSH term) exists or where PubMed’s automatic mapping process (identifying a MeSH term and including it in a search formulation) fails. Searching for instance for articles on ‘“Knowledge Transfer”’ (for which no corresponding MeSH or entry term exists) will retrieve a set of some 530 studies in PubMed (as of August 2011); Anne O’Tate’s analysis suggests that MeSH terms like "Diffusion of Innovation" or "Information Dissemination" may be suitable additional concepts to retrieve a more ‘sensitive’ (comprehensive) set of references. This method of identifying possible MeSH terms is not available on PubMed.


Authors

This option may help with identifying authors who have written frequently about a given subject, or may help with identifying possible experts or peer reviewers


Journals

Identifying journals which publish papers on the subject under investigation may assist with selecting suitable journals to consider for manuscripts or for detailed scanning for relevant articles ('hand searching') not found by the search on PubMed.


Other fields

Author affiliations (addresses) and the years of publication can also be analysed. ‘Important words’ from titles and abstracts which may " ..have more frequent occurrences in the result subset than in the
MEDLINE MEDLINE (Medical Literature Analysis and Retrieval System Online, or MEDLARS Online) is a bibliographic database of life sciences and biomedical information. It includes bibliographic information for articles from academic journals covering medic ...
as a whole, thus they distinguish the result subset from the rest of MEDLINE" can be identified and help with further refining a search on PubMed.


History

Anne O'Tate (a pun on the word ‘annotate’) was developed by Neil R Smalheiser and a team of researchers from the
University of Chicago The University of Chicago (UChicago, Chicago, or UChi) is a Private university, private research university in Chicago, Illinois, United States. Its main campus is in the Hyde Park, Chicago, Hyde Park neighborhood on Chicago's South Side, Chic ...
. It is part of the Arrowsmith Project, which developed tools such as “Arrowsmith” proper, a text-comparison application, "Adam", a database of medical abbreviations, and ‘’Author-ity’’ (an author-disambiguation tool), "Compendium", a list of biomedical text mining tools, and Anne O’Tate. The Project is based on research led by
Don R. Swanson Don R. Swanson (October 10, 1924 – November 18, 2012) was an American information scientist, most known for his work in literature-based discovery in the biomedical domain. His particular method has been used as a model for further work, and is ...
at the
University of Chicago The University of Chicago (UChicago, Chicago, or UChi) is a Private university, private research university in Chicago, Illinois, United States. Its main campus is in the Hyde Park, Chicago, Hyde Park neighborhood on Chicago's South Side, Chic ...
which hosted the original tool. Further research was led by Neil R. Smalheiser at the
University of Illinois at Chicago The University of Illinois Chicago (UIC) is a public research university in Chicago, Illinois, United States. Its campus is in the Near West Side community area, adjacent to the Chicago Loop. The second campus established under the Universi ...
, with funding from the
National Institutes of Health The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research. It was founded in 1887 and is part of the United States Department of Health and Human Service ...
.


Other PubMed text-mining applications

A wide range of text-mining applications for PubMed have been developed, using their own interface, such as GoPubMed, ClusterMed, or PubReMiner. Only Anne O’Tate uses PubMed’s standard interface, search syntax, and some of its functionality.


References


External links


Anne O'TatePubMed Home Page
* {{cite web , title= The Arrowsmith Project Homepage , url=http://arrowsmith.psych.uic.edu/arrowsmith_uic/index.html , publisher= University of Illinois at Chicago, Department of Psychiatry , date= December 20, 2007 , access-date= July 4, 2011 Data mining and machine learning software Data management software Medical databases