Amur virus (AMRV) is a
zoonotic
A zoonosis (; plural zoonoses) or zoonotic disease is an infectious disease of humans caused by a pathogen (an infectious agent, such as a bacterium, virus, parasite or prion) that has jumped from a non-human (usually a vertebrate) to a human. ...
negative-sense single-stranded RNA virus
In molecular biology and genetics, the sense of a nucleic acid molecule, particularly of a strand of DNA or RNA, refers to the nature of the roles of the strand and its complement in specifying a sequence of amino acids. Depending on the contex ...
. It may be a member of the genus ''
Orthohantavirus
''Orthohantavirus'' is a genus of single-stranded, enveloped, negative-sense RNA viruses in the family '' Hantaviridae'' within the order ''Bunyavirales''. Members of this genus may be called orthohantaviruses or simply hantaviruses.
Orthohantav ...
'', but it has not be definitively classified as a
species
In biology, a species is the basic unit of classification and a taxonomic rank of an organism, as well as a unit of biodiversity. A species is often defined as the largest group of organisms in which any two individuals of the appropriate s ...
and may only be a
strain
Strain may refer to:
Science and technology
* Strain (biology), variants of plants, viruses or bacteria; or an inbred animal used for experimental purposes
* Strain (chemistry), a chemical stress of a molecule
* Strain (injury), an injury to a mu ...
.
It has been identified as a causative agent of
hemorrhagic fever with renal syndrome
Hantavirus hemorrhagic fever with renal syndrome (HFRS) is a group of clinically similar illnesses caused by species of hantaviruses. It is also known as Korean hemorrhagic fever and epidemic hemorrhagic fever. It is found in Europe, Asia, and A ...
.
Genome
The complete genome sequence Amur virus has been isolated from a sample obtained from ''
Apodemus peninsulae'' in Northeastern China.
AMRV strains from China and Far East and
Soochong virus (SOOV) (especially SOO-1/2 strains from Northeastern Korea) were found to share high identities of nucleotide sequences and were
monophyletic distinct from ''
Apodemus agrarius''
HTNV. Two genetic sublineages of SOOV exist, but findings suggest that AMRV and SOOV are different strains of the same hantavirus.
Reservoir
The virus is reported to be carried by
Korean field mice (''Apodemus peninsulae'') in the Far East of Russia, China, and Korea.
See also
*
Hantaviruses
''Orthohantavirus'' is a genus of single-stranded, enveloped, negative-sense RNA viruses in the family '' Hantaviridae'' within the order ''Bunyavirales''. Members of this genus may be called orthohantaviruses or simply hantaviruses.
Orthohantav ...
*
Viral hemorrhagic fever
Viral hemorrhagic fevers (VHFs) are a diverse group of animal and human illnesses in which fever and hemorrhage are caused by a viral infection. VHFs may be caused by five distinct families of RNA viruses: the families '' Filoviridae'', ''Flav ...
*
Pulmonary-renal syndrome
Pulmonary-renal syndrome (PRS) is a rare medical syndrome in which respiratory failure involving bleeding in the lungs and kidney failure (glomerulonephritis) occur. PRS is associated with a high rate of morbidity and death. The term was first used ...
*
RNA virus
*
Murinae
The Old World rats and mice, part of the subfamily Murinae in the family Muridae, comprise at least 519 species. Members of this subfamily are called murines. In terms of species richness, this subfamily is larger than all mammal families excep ...
References
External links
IUCN*
*
{{Taxonbar, from=Q16242878
Viral diseases
Hantaviridae
Hemorrhagic fevers
Rodent-carried diseases
Old World rats and mice