α-Pyrrolidinopentiothiophenone (also known as α-PVT) is a synthetic

stimulant Stimulants (also often referred to as psychostimulants or colloquially as uppers) is an overarching term that covers many drugs including those that increase activity of the central nervous system and the body, drugs that are pleasurable and inv ...

of the

cathinone Cathinone (also known as benzoylethanamine, or β-keto-amphetamine) is a monoamine alkaloid found in the shrub '' Catha edulis'' (khat) and is chemically similar to ephedrine, cathine, methcathinone and other amphetamines. It is probably the m ...

class that has been sold online as a designer drug. It is an analogue of

α-PVP α-Pyrrolidinopentiophenone (also known as α-pyrrolidinovalerophenone, α-PVP, O-2387, β-keto-prolintane, prolintanone, or desmethylpyrovalerone) is a synthetic stimulant of the cathinone class developed in the 1960s that has been sold as a de ...

where the phenyl ring has been replaced by

thiophene Thiophene is a heterocyclic compound with the formula C4H4S. Consisting of a planar five-membered ring, it is aromatic as indicated by its extensive substitution reactions. It is a colorless liquid with a benzene-like odor. In most of its reacti ...

. α-PVT was first identified in Japan in 2013. Its metabolism has been described in literature.

Side effects

α-PVT has been shown to possess high

cytotoxicity Cytotoxicity is the quality of being toxic to cells. Examples of toxic agents are an immune cell or some types of venom, e.g. from the puff adder (''Bitis arietans'') or brown recluse spider (''Loxosceles reclusa''). Cell physiology Treating cells ...

against human cell lines.

Legality

Sweden's public health agency suggested classifying α-PVT as hazardous substance on November 10, 2014. α-PVT is a controlled substance in China. α-PVT is illegal in Switzerland .

References

Cathinones Designer drugs Norepinephrine–dopamine reuptake inhibitors Pyrrolidines Stimulants Thiophenes {{nervous-system-drug-stub

Side effects

Legality

See also

References