Adam Brook is an American thoracic surgeon who is a surgical attending at St. Joseph's Medical Center in New York.

Biography

Dr. Brook received the A.B. degree in biology from

Harvard University Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher le ...

and the M.D. from

Harvard Medical School Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consi ...

. He also received the Ph.D. in genetics from the

Harvard Graduate School of Arts and Sciences The Graduate School of Arts and Sciences (GSAS) is the largest of the twelve graduate schools of Harvard University. Formed in 1872, GSAS is responsible for most of Harvard's graduate degree programs in the humanities, social sciences, and natura ...

. Brook completed his doctoral research in the laboratory of Professor

Nicholas Dyson Nicholas Dyson is Professor of Medicine at Harvard Medical School, the James and Shirley Curvey MGH Research Scholar and Scientific Director of the Massachusetts General Hospital Cancer Center. Research The Dyson Lab studies the retinoblastoma ...

of the

Massachusetts General Hospital Massachusetts General Hospital (Mass General or MGH) is the original and largest teaching hospital of Harvard Medical School located in the West End neighborhood of Boston, Massachusetts. It is the third oldest general hospital in the United Stat ...

Cancer Center. Brook subsequently completed thoracic surgical training at the University of Tennessee Health Science Center and then served as Specialist Registrar in Cardiothoracic Surgery at Barts Health NHS Trust in London, under Mr. Alan Wood. Brook is currently an attending thoracic surgeon at St. Joseph's Medical Center and the Northport

Veterans Administration The United States Department of Veterans Affairs (VA) is a Cabinet-level executive branch department of the federal government charged with providing life-long healthcare services to eligible military veterans at the 170 VA medical centers and ...

Medical Center in

New York New York most commonly refers to: * New York City, the most populous city in the United States, located in the state of New York * New York (state), a state in the northeastern United States New York may also refer to: Film and television * '' ...

Academic work

Dr. Brook is a specialist in the treatment of

lung cancer Lung cancer, also known as lung carcinoma (since about 98–99% of all lung cancers are carcinomas), is a malignant lung tumor characterized by uncontrolled cell growth in tissue (biology), tissues of the lung. Lung carcinomas derive from tran ...

. His research has focused on molecular mechanisms of carcinogenesis and on the connections between the cell cycle and development. Brook showed that the cell cycle transcription factor

E2F E2F is a group of genes that encodes a family of transcription factors (TF) in higher eukaryotes. Three of them are activators: E2F1, 2 and E2F3a. Six others act as suppressors: E2F3b, E2F4-8. All of them are involved in the cell cycle regulation a ...

was required to activate differentiation in mammalian and

Drosophila ''Drosophila'' () is a genus of flies, belonging to the family Drosophilidae, whose members are often called "small fruit flies" or (less frequently) pomace flies, vinegar flies, or wine flies, a reference to the characteristic of many species ...

post-mitotic cells. Dr. Brook has also conducted epidemiologic research demonstrating the causative inter-relationships between cigarette smoking, pulmonary disease and poverty.

References

American thoracic surgeons Living people Harvard Medical School alumni Year of birth missing (living people) {{US-physician-stub