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''Actinoplanes utahensis'' is a species of
bacteria Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among ...
and a source of the drug
acarbose Acarbose (INN) is an anti-diabetic drug used to treat diabetes mellitus type 2 and, in some countries, prediabetes. It is a generic sold in Europe and China as Glucobay (Bayer AG), in North America as Precose (Bayer Pharmaceuticals), and in Cana ...
, an
alpha-glucosidase α-Glucosidase (EC 3.2.1.20, maltase, glucoinvertase, glucosidosucrase, maltase-glucoamylase, α-glucopyranosidase, glucosidoinvertase, α-D-glucosidase, α-glucoside hydrolase, α-1,4-glucosidase, α-D-glucoside glucohydrolase; systematic na ...
inhibitor used in the treatment of
diabetes mellitus Diabetes, also known as diabetes mellitus, is a group of metabolic disorders characterized by a high blood sugar level ( hyperglycemia) over a prolonged period of time. Symptoms often include frequent urination, increased thirst and increased ap ...
.


Description

''A. utahensis'' are irregular in size and shape. They form
sporangia A sporangium (; from Late Latin, ) is an enclosure in which spores are formed. It can be composed of a single cell or can be multicellular. Virtually all plants, fungi, and many other lineages form sporangia at some point in their life cy ...
which are 5 to 18
micrometer Micrometer can mean: * Micrometer (device), used for accurate measurements by means of a calibrated screw * American spelling of micrometre The micrometre ( international spelling as used by the International Bureau of Weights and Measures; ...
s in diameter, and contain spores arranged in irregular coils. ''A. utahensis'' are motile by way of a number of
flagella A flagellum (; ) is a hairlike appendage that protrudes from certain plant and animal sperm cells, and from a wide range of microorganisms to provide motility. Many protists with flagella are termed as flagellates. A microorganism may have f ...
at one end.


History

''A. utahensis'' was originally identified by John Couch from soils collected from
Salt Lake City Salt Lake City (often shortened to Salt Lake and abbreviated as SLC) is the Capital (political), capital and List of cities and towns in Utah, most populous city of Utah, United States. It is the county seat, seat of Salt Lake County, Utah, Sal ...
's
Liberty Park Liberty Park is a elevated public park at the World Trade Center in Manhattan, New York City, overlooking the National September 11 Memorial & Museum in Lower Manhattan. The park, which opened on June 29, 2016, is located above the World Trad ...
as well as along U.S. Route 40 in Nevada.


References


External links


Type strain of ''Actinoplanes utahensis'' at Bac''Dive'' – the Bacterial Diversity Metadatabase
{{Taxonbar, from=Q25834615 Micromonosporaceae Bacteria described in 1963