ATPase ASNA1 also known as arsenical pump-driving ATPase and arsenite-stimulated ATPase is an

enzyme Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...

that in humans is encoded by the ASNA1

gene In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...

Function

ASNA1 is the human homolog of the bacterial arsA gene. In ''

E. coli ''Escherichia coli'' (),Wells, J. C. (2000) Longman Pronunciation Dictionary. Harlow ngland Pearson Education Ltd. also known as ''E. coli'' (), is a Gram-negative, facultative anaerobic, rod-shaped, coliform bacterium of the genus ''Escher ...

'', arsA ATPase is the

catalytic Catalysis () is the process of increasing the rate of a chemical reaction by adding a substance known as a catalyst (). Catalysts are not consumed in the reaction and remain unchanged after it. If the reaction is rapid and the catalyst recyc ...

component of a multisubunit

oxyanion An oxyanion, or oxoanion, is an ion with the generic formula (where A represents a chemical element and O represents an oxygen atom). Oxyanions are formed by a large majority of the chemical elements. The formulae of simple oxyanions are determine ...

pump that is responsible for resistance to

arsenical Arsenicals are chemical compounds that contain arsenic. In a military context, the term arsenical refer to toxic arsenic compounds that are used as chemical warfare agents. This include blister agents, blood agents and vomiting agents. Examples Bli ...

s and

antimonial Antimonials, in pre-modern medicine, were remedies principally containing antimony, used chiefly for emetic purposes. They might also have qualified for cathartic, diaphoretic, or simply alternative uses. Such treatments were considered unparall ...

Interactions

ASNA1 is found to interact with

FAM71D FAM71D, also known as chromosome 14 open reading frame 54 (C14orf54), is a protein that in humans is encoded by the FAM71D gene on Chromosome 14. Orthologs of FAM71D reach as far back in evolution to Reptiles, however, it is closer in homology to ...

according to

STRING String or strings may refer to: *String (structure), a long flexible structure made from threads twisted together, which is used to tie, bind, or hang other objects Arts, entertainment, and media Films * ''Strings'' (1991 film), a Canadian anim ...

Function

Interactions

References

External links

Further reading