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Various fringe theories have arisen to speculate about purported alternative origins for the
human immunodeficiency virus The human immunodeficiency viruses (HIV) are two species of ''Lentivirus'' (a subgroup of retrovirus) that infect humans. Over time, they cause AIDS, acquired immunodeficiency syndrome (AIDS), a condition in which progressive failure of the ...
(HIV) and the
acquired immunodeficiency syndrome Human immunodeficiency virus infection and acquired immunodeficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV), a retrovirus. Following initial infection an individual ma ...
(AIDS), with claims ranging from it being due to accidental exposure to supposedly purposeful acts. Several inquiries and investigations have been carried out as a result, and each of these theories has consequently been determined to be based on unfounded and/or false information. HIV has been shown to have evolved from or be closely related to the
simian immunodeficiency virus ''Simian immunodeficiency virus'' (''SIV'') is a species of retrovirus that cause persistent infections in at least 45 species of non-human primates. Based on analysis of strains found in four species of monkeys from Bioko Island, which was isola ...
(SIV) in West Central Africa sometime in the early 20th century. HIV was discovered in the 1980s by the French scientist
Luc Montagnier Luc Montagnier (; , ; 18 August 1932 – 8 February 2022) was a French virologist and joint recipient, with and , of the 2008 Nobel Prize in Physiology or Medicine for his discovery of the human immunodeficiency virus (HIV). He worked as a res ...
. Before the 1980s, HIV was an unknown deadly disease.


Discredited theories


Smallpox vaccination theory

In 1987 there was some consideration given to the possibility that the "AIDS epidemic may have been triggered by the mass vaccination campaign which eradicated
smallpox Smallpox was an infectious disease caused by variola virus (often called smallpox virus) which belongs to the genus Orthopoxvirus. The last naturally occurring case was diagnosed in October 1977, and the World Health Organization (WHO) c ...
". An article in ''
The Times ''The Times'' is a British daily national newspaper based in London. It began in 1785 under the title ''The Daily Universal Register'', adopting its current name on 1 January 1788. ''The Times'' and its sister paper ''The Sunday Times'' (fou ...
'' suggested this, attributing to an unnamed "adviser to WHO" the quote "I believe the smallpox vaccine theory is the explanation to the explosion of AIDS". It is now thought that the
smallpox vaccine The smallpox vaccine is the first vaccine to be developed against a contagious disease. In 1796, British physician Edward Jenner demonstrated that an infection with the relatively mild cowpox virus conferred immunity against the deadly smallpox ...
causes serious complications for people who already have impaired immune systems, and the ''Times'' article described the case of a military recruit with "dormant HIV" who died within months of receiving it. But no citation was provided regarding people who did not previously have HIV. Currently HIV is considered to be a
contraindication In medicine, a contraindication is a condition that serves as a reason not to take a certain medical treatment due to the harm that it would cause the patient. Contraindication is the opposite of indication, which is a reason to use a certain tre ...
for the smallpox vaccine—both for an infected person and their sexual partners and household members. Some conspiracy theorists propose an expanded hypothesis in which the smallpox vaccine was deliberately contaminated with HIV. In contrast, a research article was published in 2010 suggesting that it might have been the actual eradication of smallpox and the subsequent "ending" of the mass vaccination campaign that contributed to the sudden emergence of HIV. The theory was the possibility that immunization against smallpox "might play a role in providing an individual with some degree of protection to subsequent HIV infection and/or disease progression." Regardless of the effects of the smallpox vaccine itself, its use in practice in Africa is one of the categories of un-sterile injections that may have contributed to the spread and mutation of the immunodeficiency viruses.


Hepatitis B vaccine (HBV) theory

The dermatologist Alan Cantwell, in self-published books entitled ''AIDS and the Doctors of Death: An Inquiry into the Origin of the AIDS Epidemic'' (1988) and ''Queer Blood: The Secret AIDS Genocide Plot'' (1993), said that HIV is a
genetically modified organism A genetically modified organism (GMO) is any organism whose genetic material has been altered using genetic engineering techniques. The exact definition of a genetically modified organism and what constitutes genetic engineering varies, with ...
developed by U.S. Government scientists. The virus was then introduced into the population through
hepatitis B Hepatitis B is an infectious disease caused by the ''Hepatitis B virus'' (HBV) that affects the liver; it is a type of viral hepatitis. It can cause both acute and chronic infection. Many people have no symptoms during an initial infection. Fo ...
(via the
hepatitis B vaccine Hepatitis B vaccine is a vaccine that prevents hepatitis B. The first dose is recommended within 24 hours of birth with either two or three more doses given after that. This includes those with poor immune function such as from HIV/AIDS and th ...
) experiments performed on gay and bisexual men between 1978 and 1981 in major U.S. cities. Cantwell claims that these experiments were directed by Wolf Szmuness, and that there was an ongoing government cover-up of the origins of the AIDS epidemic. Similar theories have been advanced by Robert B. Strecker, Matilde Krim, and
Milton William Cooper Milton William "Bill" Cooper (May 6, 1943 – November 5, 2001) was an American conspiracy theorist, radio broadcaster, and author known for his 1991 book ''Behold a Pale Horse'', in which he warned of multiple global conspiracies, some in ...
.


Oral polio vaccine (OPV) theory

In the 1999 version of his
OPV AIDS hypothesis The oral polio vaccine (OPV) AIDS hypothesis is a now-discredited hypothesis that the AIDS pandemic originated from live polio vaccines prepared in Common chimpanzee, chimpanzee tissue cultures, accidentally contaminated with simian immunodeficie ...
, Edward Hooper proposed that early batches of the
oral polio vaccine Polio vaccines are vaccines used to prevent poliomyelitis (polio). Two types are used: an inactivated poliovirus given by injection (IPV) and a weakened poliovirus given by mouth (OPV). The World Health Organization (WHO) recommends all child ...
(OPV) grown in cultures of chimpanzee kidney cells, infected with a chimpanzee virus, were the original source of HIV-1 in Central Africa. A vial of the batch most strongly implicated by Hooper was found in storage in the UK, and analysis found no HIV/SIV sequences or chimpanzee cellular components, but did find traces of macaque mitochondria. Analysis of five samples of OPV in storage at the
Wistar Institute The Wistar Institute () is an independent, nonprofit research institution in biomedical science, with expertise in oncology, immunology, infectious disease and vaccine research. Located on the campus of the University of Pennsylvania, Wistar was ...
, including one from a batch used in the Belgian Congo between 1958 and 1960, found no chimpanzee DNA.Sarah Ramsay 28 April 200
"Cold water downstream from The River"
''The Lancet'' 357 (9265) p.1343
Other
molecular biology Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The study of chemical and physi ...
and
phylogenetic In biology, phylogenetics (; from Greek φυλή/ φῦλον [] "tribe, clan, race", and wikt:γενετικός, γενετικός [] "origin, source, birth") is the study of the evolutionary history and relationships among or within groups o ...
studies also contradict the hypothesis, and
scientific consensus Scientific consensus is the generally held judgment, position, and opinion of the majority or the supermajority of scientists in a particular field of study at any particular time. Consensus is achieved through scholarly communication at confe ...
regards it as disproven. A 2004 article in the journal ''
Nature Nature, in the broadest sense, is the physics, physical world or universe. "Nature" can refer to the phenomenon, phenomena of the physical world, and also to life in general. The study of nature is a large, if not the only, part of science. ...
'' described the hypothesis as "refuted".


Additional theories

These theories generally attribute HIV's origin to the
US government The federal government of the United States (U.S. federal government or U.S. government) is the national government of the United States, a federal republic located primarily in North America, composed of 50 states, a city within a feder ...
or its contractors:


Created at Fort Detrick

Jakob Segal Jakob Segal (17 April 1911 – 30 September 1995) was a Russian-born German biology professor at Humboldt University of Berlin in the former East Germany. He was one of the advocates of the conspiracy theory that HIV was created by the United St ...
(1911–1995), a professor at
Humboldt University Humboldt-Universität zu Berlin (german: Humboldt-Universität zu Berlin, abbreviated HU Berlin) is a German public research university in the central borough of Mitte in Berlin. It was established by Frederick William III on the initiative of ...
in then-
East Germany East Germany, officially the German Democratic Republic (GDR; german: Deutsche Demokratische Republik, , DDR, ), was a country that existed from its creation on 7 October 1949 until its dissolution on 3 October 1990. In these years the state ...
, proposed that HIV was engineered at a U.S. military laboratory at
Fort Detrick Fort Detrick () is a United States Army Futures Command installation located in Frederick, Maryland. Historically, Fort Detrick was the center of the U.S. biological weapons program from 1943 to 1969. Since the discontinuation of that program, i ...
, by splicing together two other viruses, Visna and
HTLV-1 Human T-cell lymphotropic virus type 1 or human T-lymphotropic virus (HTLV-I), also called the adult T-cell lymphoma virus type 1, is a retrovirus of the human T-lymphotropic virus (HTLV) family that has been implicated in several kinds of diseas ...
. According to his theory, the new virus, created between 1977 and 1978, was tested on prison inmates who had volunteered for the experiment in exchange for early release. He further suggested that it was through these prisoners that the virus was spread to the population at large. At the end of the
Cold War The Cold War is a term commonly used to refer to a period of geopolitical tension between the United States and the Soviet Union and their respective allies, the Western Bloc and the Eastern Bloc. The term '' cold war'' is used because the ...
, former
KGB The KGB (russian: links=no, lit=Committee for State Security, Комитет государственной безопасности (КГБ), a=ru-KGB.ogg, p=kəmʲɪˈtʲet ɡəsʊˈdarstvʲɪn(ː)əj bʲɪzɐˈpasnəsʲtʲɪ, Komitet gosud ...
agents
Vasili Mitrokhin Vasili Nikitich Mitrokhin (russian: link=no, Васи́лий Ники́тич Митро́хин; March 3, 1922 – January 23, 2004) was a major and senior archivist for the Soviet Union's foreign intelligence service, the First Chief Dir ...
and
Oleg Gordievsky Oleg Antonovich Gordievsky, CMG (; born 10 October 1938) is a former colonel of the KGB who became KGB resident-designate (''rezident'') and bureau chief in London, and was a double agent, providing information to the British Secret Intelli ...
independently revealed that the Fort Detrick hypothesis was a propaganda operation devised by the KGB's
First Chief Directorate The First Main Directorate () of the Committee for State Security under the USSR council of ministers (PGU KGB) was the organization responsible for foreign operations and intelligence activities by providing for the training and management of cove ...
codenamed "
Operation INFEKTION Operation INFEKTION was an active measure disinformation campaign run by the KGB in the 1980s to plant the idea that the United States had invented HIV/AIDS as part of a biological weapons research project at Fort Detrick, Maryland. Historian ...
". This revelation was later supported by officer Günther Bohnensack of section X of East Germany's
Main Directorate for Reconnaissance The Main Directorate for Reconnaissance (german: ; german: , ) was the foreign intelligence service of the Ministry of State Security (''Stasi''), the main security agency of the German Democratic Republic (East Germany), from 1955 to 1990. ...
. It is known that Segal was in close contact with Russian KGB officers and Mitrokhin mentioned him as a central asset of the operation.Johanna Lutterroth
''Aids-Verschwörung. Das Propaganda-Virus des KGB''
Spiegel Geschichte, 2012-06-26 (German)
It is not entirely clear whether Segal pursued the hypothesis independently on his own accord or whether he was simply following orders. Segal himself always denied the latter and kept pursuing the hypothesis even after the operation had been canceled and the Cold War had ended.


Conspiracy to decrease the population

In ''Behold a Pale Horse'' (1991), radio broadcaster and author
Milton William Cooper Milton William "Bill" Cooper (May 6, 1943 – November 5, 2001) was an American conspiracy theorist, radio broadcaster, and author known for his 1991 book ''Behold a Pale Horse'', in which he warned of multiple global conspiracies, some in ...
(1943–2001) proposed that
AIDS Human immunodeficiency virus infection and acquired immunodeficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV), a retrovirus. Following initial infection an individual m ...
was the result of a conspiracy to decrease the populations of
blacks Black is a racialized classification of people, usually a political and skin color-based category for specific populations with a mid to dark brown complexion. Not all people considered "black" have dark skin; in certain countries, often in ...
,
Hispanics The term ''Hispanic'' ( es, hispano) refers to people, cultures, or countries related to Spain, the Spanish language, or Hispanidad. The term commonly applies to countries with a cultural and historical link to Spain and to viceroyalties former ...
, and
homosexuals Homosexuality is romantic attraction, sexual attraction, or sexual behavior between members of the same sex or gender. As a sexual orientation, homosexuality is "an enduring pattern of emotional, romantic, and/or sexual attractions" to pe ...
.


Prevalence of conspiracy beliefs

According to Phil Wilson, executive director of the Black AIDS Institute in Los Angeles, conspiracy theories are becoming a barrier to the prevention of AIDS since people start to believe that no matter what measures they take, they can still be prone to contracting this disease. A 2005 study suggests this makes them less careful when engaging in practices that put them at risk because they believe there is no point. "Nearly half of the 500 African Americans surveyed said that HIV is man-made. More than one-quarter said they believed that AIDS was produced in a government laboratory, and 12 percent believed it was created and spread by the CIA ... At the same time, 75 percent said they believed medical and public health agencies are working to stop the spread of AIDS in black communities."


Prominent endorsers of discredited theories


Nation of Islam

The
Nation of Islam The Nation of Islam (NOI) is a religious and political organization founded in the United States by Wallace Fard Muhammad in 1930. A black nationalist organization, the NOI focuses its attention on the African diaspora, especially on African ...
endorses the view that governments and pharmaceutical companies have pursued genocidal racist policies including the creation and spread of HIV. Consequently, the group called for a boycott of U.S.-sponsored vaccination programs for children. Leonard Horowitz has been cited as influential in the boycott decision.


Wangari Maathai

The 2004
Nobel Peace Prize The Nobel Peace Prize is one of the five Nobel Prizes established by the will of Swedish industrialist, inventor and armaments (military weapons and equipment) manufacturer Alfred Nobel, along with the prizes in Nobel Prize in Chemistry, Chemi ...
laureate and environmental activist
Wangari Maathai Wangarĩ Muta Maathai (; 1 April 1940 – 25 September 2011) was a Kenyan social, environmental and a political activist and the first African woman to win the Nobel Peace Prize. As a beneficiary of the Kennedy Airlift, she studied in the Un ...
was asked by a ''Time'' magazine interviewer if she stood by a previous alleged claim that "AIDS is a biological weapon manufactured by the developed world to wipe out the black race". Maathai responded, "I have no idea who created AIDS and whether it is a biological agent or not. But I do know things like that don't come from the moon. ... I guess there is some truth that must not be too exposed." Maathai subsequently issued a written statement in December 2004: "I neither say nor believe that the virus was developed by white people or white powers in order to destroy the African people. Such views are wicked and destructive."from the Green Belt Movement website- Wangari Maathai's "The Challenge of AIDS in Africa"
.


Manto Tshabalala-Msimang

In 2000 South Africa's Minister of Health
Manto Tshabalala-Msimang Mantombazana "Manto" Edmie Tshabalala-Msimang (née Mali; 9 October 1940 – 16 December 2009) was a South African politician. She was Deputy Minister of Justice from 1996 to 1999 and served as Minister of Health from 1999 to 2008 under Preside ...
received criticism for distributing the chapter from Cooper's book discussing this theory to senior South African government officials.
Nicoli Nattrass Nicoli Nattrass (born 30 May 1961) is a South African development economist who is professor of economics at the University of Cape Town (UCT). She is the co-director of the Institute for Communities and Wildlife in Africa (iCWild) and was the f ...
, a longtime critic of AIDS denialists, criticized Tshabalala-Msimang for lending legitimacy to Cooper's theories and disseminating them in Africa.


See also

*
Duesberg hypothesis The Duesberg hypothesis is the claim that AIDS is not caused by HIV, but, instead, that AIDS is caused by noninfectious factors such as recreational and pharmaceutical drug use and that HIV is merely a harmless passenger virus. The hypothesis wa ...
*
History of HIV/AIDS AIDS is caused by a human immunodeficiency virus (HIV), which originated in non-human primates in Central and West Africa. While various sub-groups of the virus acquired human infectivity at different times, the present pandemic had its origins ...
** Timeline of HIV/AIDS *
HIV/AIDS denialism HIV/AIDS denialism is the belief, despite conclusive evidence to the contrary, that the human immunodeficiency virus (HIV) does not cause acquired immune deficiency syndrome (AIDS). Some of its proponents reject the existence of HIV, while othe ...
*
HIV/AIDS denialism in South Africa In South Africa, HIV/AIDS denialism had a significant impact on public health policy from 1999 to 2008, during the presidency of Thabo Mbeki. Mbeki criticized the scientific consensus that HIV is the cause of AIDS beginning shortly after his electi ...
*
Operation INFEKTION Operation INFEKTION was an active measure disinformation campaign run by the KGB in the 1980s to plant the idea that the United States had invented HIV/AIDS as part of a biological weapons research project at Fort Detrick, Maryland. Historian ...
* Oral polio vaccine AIDS hypothesis *
SV40 SV40 is an abbreviation for simian vacuolating virus 40 or simian virus 40, a polyomavirus that is found in both monkeys and humans. Like other polyomaviruses, SV40 is a DNA virus that has the potential to cause tumors in animals, but most often ...
*
Zoonosis A zoonosis (; plural zoonoses) or zoonotic disease is an infectious disease of humans caused by a pathogen (an infectious agent, such as a bacterium, virus, parasite or prion) that has jumped from a non-human (usually a vertebrate) to a human. ...


References


External links

* {{HIV and AIDS AIDS origin hypotheses Biological warfare Medical-related conspiracy theories Science and technology-related conspiracy theories