Wolf Szmuness
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Wolf Szmuness
Wolf Szmuness (March 12, 1919 – June 6, 1982) was a Polish-born epidemiologist who emigrated to and worked in the United States. He conducted research at the New York Blood Center and, from 1973, he was director of the Center's epidemiology laboratory. He designed and conducted the trials for the first vaccine to prove effective against hepatitis B. European beginnings Szmuness was born in Warsaw, Poland on 12 March 1919. He studied medicine in Italy, but he returned to be with his family around the Nazi German invasion of Poland in 1939. As the Germans and Soviets occupied Poland, Szmuness was separated from his family, who were later killed by the Germans. Trapped in the Communist-occupied part of Poland, Szmuness traveled eastward to escape the advancing Nazis. He asked the Soviets to let him fight the Germans but was sent to Siberia as a prisoner. Following a year of hard labour in the prison camp, Szmuness was appointed head of sanitary conditions. He later became the head e ...
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Epidemiology
Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and determinants of health and disease conditions in a defined population. It is a cornerstone of public health, and shapes policy decisions and evidence-based practice by identifying risk factors for disease and targets for preventive healthcare. Epidemiologists help with study design, collection, and statistical analysis of data, amend interpretation and dissemination of results (including peer review and occasional systematic review). Epidemiology has helped develop methodology used in clinical research, public health studies, and, to a lesser extent, basic research in the biological sciences. Major areas of epidemiological study include disease causation, transmission, outbreak investigation, disease surveillance, environmental epidemiology, forensic epidemiology, occupational epidemiology, screening, biomonitoring, and comparisons of treatment effects such as in clinical trials. ...
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New York Hospital-Cornell Medical Center
New is an adjective referring to something recently made, discovered, or created. New or NEW may refer to: Music * New, singer of K-pop group The Boyz Albums and EPs * ''New'' (album), by Paul McCartney, 2013 * ''New'' (EP), by Regurgitator, 1995 Songs * "New" (Daya song), 2017 * "New" (Paul McCartney song), 2013 * "New" (No Doubt song), 1999 *"new", by Loona from '' Yves'', 2017 *"The New", by Interpol from ''Turn On the Bright Lights'', 2002 Acronyms * Net economic welfare, a proposed macroeconomic indicator * Net explosive weight, also known as net explosive quantity * Network of enlightened Women, a conservative university women's organization * Next Entertainment World, a South Korean film distribution company Identification codes * Nepal Bhasa language ISO 639 language code * New Century Financial Corporation (NYSE stock abbreviation) * Northeast Wrestling, a professional wrestling promotion in the northeastern United States Transport * New Orleans Lakefront Ai ...
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Sexual Orientation And Medicine
Timeline of events related to sexual orientation and medicine 19th century 1886 *Dr. Richard Freiherr von Krafft-Ebing, a German psychiatrist, published a study of sexual perversity. 20th century 1948 *''Sexual Behavior in the Human Male'', the first "Kinsey Report", was published by Dr. Alfred Kinsey. 1953 *''Sexual Behavior in the Human Female'', the second "Kinsey Report", was published by Dr. Alfred Kinsey. 1957 *The Society for the Scientific Study of Sexuality was founded to encourage the rigorous systematic study of sexuality. 1973 *The American Psychiatric Association voted to remove homosexuality from the Diagnostic and Statistical Manual of Mental Disorders (DSM). 1975 * The Gay and Lesbian Health Caucus of the American Public Health Association is founded. 1977 *The Bay Area Physicians for Human Rights was founded in San Francisco as a support group for gay and lesbian medical students, residents, and other health care providers. The group claims to be the first ...
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1982 Deaths
__NOTOC__ Year 198 (CXCVIII) was a common year starting on Sunday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Sergius and Gallus (or, less frequently, year 951 ''Ab urbe condita''). The denomination 198 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire *January 28 **Publius Septimius Geta, son of Septimius Severus, receives the title of Caesar. **Caracalla, son of Septimius Severus, is given the title of Augustus. China *Winter – Battle of Xiapi: The allied armies led by Cao Cao and Liu Bei defeat Lü Bu; afterward Cao Cao has him executed. By topic Religion * Marcus I succeeds Olympianus as Patriarch of Constantinople (until 211). Births * Lu Kai (or Jingfeng), Chinese official and general (d. 269) * Quan Cong, Chinese general and advisor (d ...
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1919 Births
Events January * January 1 ** The Czechoslovak Legions occupy much of the self-proclaimed "free city" of Pressburg (now Bratislava), enforcing its incorporation into the new republic of Czechoslovakia. ** HMY ''Iolaire'' sinks off the coast of the Hebrides; 201 people, mostly servicemen returning home to Lewis and Harris, are killed. * January 2– 22 – Russian Civil War: The Red Army's Caspian-Caucasian Front begins the Northern Caucasus Operation against the White Army, but fails to make progress. * January 3 – The Faisal–Weizmann Agreement is signed by Emir Faisal (representing the Arab Kingdom of Hejaz) and Zionist leader Chaim Weizmann, for Arab–Jewish cooperation in the development of a Jewish homeland in Palestine, and an Arab nation in a large part of the Middle East. * January 5 – In Germany: ** Spartacist uprising in Berlin: The Marxist Spartacus League, with the newly formed Communist Party of Germany and the Independent Social De ...
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Deaths From Lung Cancer
Death is the irreversible cessation of all biological functions that sustain an organism. For organisms with a brain, death can also be defined as the irreversible cessation of functioning of the whole brain, including brainstem, and brain death is sometimes used as a legal definition of death. The remains of a former organism normally begin to decompose shortly after death. Death is an inevitable process that eventually occurs in almost all organisms. Death is generally applied to whole organisms; the similar process seen in individual components of an organism, such as cells or tissues, is necrosis. Something that is not considered an organism, such as a virus, can be physically destroyed but is not said to die. As of the early 21st century, over 150,000 humans die each day, with ageing being by far the most common cause of death. Many cultures and religions have the idea of an afterlife, and also may hold the idea of judgement of good and bad deeds in one's life ( h ...
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Haiti
Haiti (; ht, Ayiti ; French: ), officially the Republic of Haiti (); ) and formerly known as Hayti, is a country located on the island of Hispaniola in the Greater Antilles archipelago of the Caribbean Sea, east of Cuba and Jamaica, and south of The Bahamas and the Turks and Caicos Islands. It occupies the western three-eighths of the island which it shares with the Dominican Republic. To its south-west lies the small Navassa Island, which is claimed by Haiti but is disputed as a United States territory under federal administration."Haiti"
''Encyclopædia Britannica''.
Haiti is in size, the third largest country in the Caribbean by area, and has an estimated population of 11.4 million, making it the most populous country in the Caribb ...
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Origin Of AIDS
AIDS is caused by a human immunodeficiency virus (HIV), which originated in non-human primates in Central and West Africa. While various sub-groups of the virus acquired human infectivity at different times, the present pandemic had its origins in the emergence of one specific strain – HIV-1 subgroup M – in Léopoldville in the Belgian Congo (now Kinshasa in the Democratic Republic of the Congo) in the 1920s. There are two types of HIV: HIV-1 and HIV-2. HIV-1 is more virulent, easily transmitted and is the cause of the vast majority of HIV infections globally. The pandemic strain of HIV-1 is closely related to a virus found in chimpanzees of the subspecies ''Pan troglodytes troglodytes'', which live in the forests of the Central African nations of Cameroon, Equatorial Guinea, Gabon, the Republic of the Congo, and the Central African Republic. HIV-2 is less transmittable and is largely confined to West Africa, along with its closest relative, a virus of the sooty mangabey ( ...
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Discredited AIDS Origins Theories
Various fringe theories have arisen to speculate about purported alternative origins for the human immunodeficiency virus (HIV) and the acquired immunodeficiency syndrome (AIDS), with claims ranging from it being due to accidental exposure to supposedly purposeful acts. Several inquiries and investigations have been carried out as a result, and each of these theories has consequently been determined to be based on unfounded and/or false information. HIV has been shown to have evolved from or be closely related to the simian immunodeficiency virus (SIV) in West Central Africa sometime in the early 20th century. HIV was discovered in the 1980s by the French scientist Luc Montagnier. Before the 1980s, HIV was an unknown deadly disease. Discredited theories Smallpox vaccination theory In 1987 there was some consideration given to the possibility that the "AIDS epidemic may have been triggered by the mass vaccination campaign which eradicated smallpox". An article in ''The Times'' su ...
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Vaccine Trials
A vaccine trial is a clinical trial that aims at establishing the safety and efficacy of a vaccine prior to it being licensed. A vaccine candidate drug is first identified through preclinical evaluations that could involve high throughput screening and selecting the proper antigen to invoke an immune response. Some vaccine trials may take months or years to complete, depending on the time required for the subjects to react to the vaccine and develop the required antibodies. Preclinical stage Preclinical development stages are necessary to determine the immunogenicity potential and safety profile for a vaccine candidate. This is also the stage in which the drug candidate may be first tested in laboratory animals prior to moving to the Phase I trials. Vaccines such as the oral polio vaccine have been first tested for adverse effects and immunogenicity in monkeys as well as non-human primates and lab mice. Recent scientific advances have helped to use transgenic animals ...
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Natural History Of Disease
The natural history of disease is the course a disease takes in individual people from its pathological onset ("inception") until its resolution (either through complete recovery or eventual death). The inception of a disease is not a firmly defined concept. The natural history of a disease is sometimes said to start at the moment of exposure to causal agents. Knowledge of the natural history of disease ranks alongside causal understanding in importance for disease prevention and control. Natural history of disease is one of the major elements of descriptive epidemiology. As an example, the cartilage of the knee, trapeziometacarpal and other joints deteriorates with age in most humans (osteoarthritis). There are no disease-modifying treatments for osteoarthritis---no way to slow, arrest, or reverse this pathophysiological process. There are only palliative/symptomatic treatments such as analgesics and exercises. In contrast, consider rheumatoid arthritis, a systemic inflammatory ...
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Lung Cancer
Lung cancer, also known as lung carcinoma (since about 98–99% of all lung cancers are carcinomas), is a malignant lung tumor characterized by uncontrolled cell growth in tissue (biology), tissues of the lung. Lung carcinomas derive from transformed, malignant cells that originate as epithelial cells, or from tissues composed of epithelial cells. Other lung cancers, such as the rare sarcomas of the lung, are generated by the malignant transformation of connective tissues (i.e. nerve, fat, muscle, bone), which arise from mesenchymal cells. Lymphomas and melanomas (from lymphoid and melanocyte cell lineages) can also rarely result in lung cancer. In time, this uncontrolled neoplasm, growth can metastasis, metastasize (spreading beyond the lung) either by direct extension, by entering the lymphatic circulation, or via hematogenous, bloodborne spread – into nearby tissue or other, more distant parts of the body. Most cancers that originate from within the lungs, known as primary ...
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